right OFC for Obsessive-Compulsive Disorder

"This medical trial is open to individuals 18-80 years of age. There are 23 studies for minors and 67 separate trials for seniors over 65."

"The clinical trial is recruiting 180 individuals with a DSM-5 diagnosis of obsessive compulsive disorder (OCD) who have attained the age of majority but are below 80 years old. In order to qualify, they must display moderate severity in OCD as determined by their YBOCS score and demonstrate stable use of SRI medication for 8 weeks prior to joining the study. The candidates also need to have unsuccessfully gone through an APA approved first line treatment or rejected these treatments due to individual reasons, be able to provide informed consent, tolerate all required procedures, and pass screening forms at Stanford CNI without any contraindications."

"According to clinicaltrials.gov, recruitment for this medical study is still open. It was initially advertised on 15th January 2021 and the most recent update occurred during 20th December of the same year."

"The primary outcome measure of this clinical trial, assessed after the duration of treatment, is the percentage change in Yale-Brown Obsessive-Compulsive Scale (YBOCS). Secondary outcomes encompass changes from baseline functional connectivity to 1 month post-treatment via resting state fMRI between subcallosal cingulate and default mode network as well as within it. Furthermore, there will be a Percentage Change in Patient Health Questionnaire 9 (PHQ9) scores with higher scores representing greater severity, and finally a comparison between baseline and each day's treatment regarding functional connectivities."