Acceptance Commitment Therapy for Methamphetamine Addiction

Overseen By Harminder Paul

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Centre for Addiction and Mental Health

Disqualifiers: Psychosis, Suicidal ideation, Cognitive deficits

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 19

Duration: 8 weeks

60 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This study aims to assess the feasibility, acceptability and preliminary effectiveness of Acceptance Commitment Therapy, in conjunction with motivation enhancement, and the use of the ChillTime App, in reducing methamphetamine use in women with MUD with or without co-occurring psychiatric disorders. This intervention is designed to be delivered remotely (e.g., participants can complete the entire study from home), with the option for in person attendance if it is not feasible or safe for participants to attend from home.

Who Is on the Research Team?

Bernard Le Foll, MD

Principal Investigator

Centre for Addiction and Mental Health

Are You a Good Fit for This Trial?

This trial is for women and gender non-conforming individuals with methamphetamine use disorder (MUD), who can consent, communicate in English, and have a clinician. It's not for those with severe cognitive issues, untreated psychosis, or intense suicidal thoughts needing hospitalization.

Inclusion Criteria

Adequate English language abilities

I am over 18 years old.

I understand and can agree to the study's procedures and risks.

Exclusion Criteria

I am able to understand and participate in the study.

Experiencing acute or unmedicated psychosis that would reasonably prevent them from engaging in and/or benefiting from the intervention

Experiencing acute and severe suicidal ideation such that institutionalization and supervised care is warranted

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

1 visit (virtual or in-person)

Motivation Building

Participants undergo a 1:1 motivation building session and receive assistance with downloading the ChillTime App

1 session

1 visit (virtual or in-person)

Treatment

Participants engage in Acceptance Commitment Therapy group sessions twice weekly for 8 weeks, with contingency management and use of the ChillTime App

8 weeks

16 sessions (virtual or in-person)

Follow-up

Participants complete clinical and quality of life assessments, and a qualitative interview to assess satisfaction and changes in drug use

1 month

1 visit (virtual or in-person)

Long-term Follow-up

Participants complete a follow-up study visit to assess long-term effects on methamphetamine use and mental health

6 months

What Are the Treatments Tested in This Trial?

Interventions

• Acceptance Commitment Therapy

Trial Overview The study tests Acceptance Commitment Therapy combined with motivation enhancement and the ChillTime App to reduce methamphetamine use remotely. Participants can join from home unless it's unsafe or unfeasible.

How Is the Trial Designed?

Group I: Intervention Arm Experimental Treatment 1 Intervention

Participants will complete the baseline session, a 1:1 motivation building session, and 8 weeks of ACT group therapy. They will then complete a final study visit and a follow-up study visit to occur 6 month after the end of therapy.

Who Is Running the Clinical Trial?

Centre for Addiction and Mental Health

Lead Sponsor

Trials

388

Recruited

84,200+