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Sulfasalazine for Pain Management in Breast Cancer
Study Summary
This trial is testing whether adding sulfasalazine to pain medication will lower the amount of opioids used and the side effects experienced by cancer patients.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I am currently taking Lapatinib or Digoxin.I have porphyria.I do not have blood, liver, or kidney diseases.I have or am at risk of having blockages in my intestines or urinary system.Your average pain score is at least 5 out of 10 for the past 3 days.I am on medications that could react with sulfasalazine.I have been experiencing pain for 6 weeks or more.You are currently involved in a legal case related to your pain.I receive payments for my pain treatment.I have cancer with moderate to severe pain and am on a stable opioid dose.I agree to participate in a study where neither I nor my doctor will know which treatment I'm receiving.You have a history of serious depression, addiction, or mental illness with hallucinations or delusions.You are allergic to sulfasalazine or related medications.I am between 18 and 94 years old, understand English, and can follow study procedures.You are expected to live for more than 6 months.I can take pills by mouth.You do not have ongoing high levels of calcium in your blood.
- Group 1: Sulfasalazine
- Group 2: Placebos
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What is the current capacity for participants in this research?
"Indeed. The information archived on clinicaltrials.gov attests that this medical trial, which was originally published on May 3rd 2021, is currently enrolling patients in a bid to acquire 40 volunteers across 2 research centres."
Are there currently any opportunities to join this trial?
"Affirmative. According to the clinicaltrials.gov registry, this research initiative is actively recruiting participants and was initially published on May 3rd 2021. A total of 40 patients are needed from two distinct locations for the study's completion."
What therapeutic benefits has Sulfasalazine been known to offer?
"Sulfasalazine is typically employed to alleviate the symptoms of polyarticular juvenile rheumatoid arthritis, chronic or unspecified. However, it may also offer relief from Crohn's disease, Ulcerative colitis, and Proctitis."
Has Sulfasalazine been sanctioned by the Federal Drug Administration?
"Although there is evidence of Sulfasalazine's safety, it lacks clinical data to support its efficacy, so we have assigned a score of 2."
Does this research encompass participants aged 85 and over?
"This study only permits patients between the ages of 18 and 94 to enroll. However, there are 108 trials that admit participants younger than 18 years old and 2862 studies that accept those older than 65."
Who fulfills the qualifications to become an enrollee of this research?
"This experiment is recruiting 40 individuals between 18 and 94 years of age who have been diagnosed with breast cancer. The following criteria must be fulfilled for candidates to qualify: providing informed consent, understanding English, 3-day NPRS average pain rating of 5/10 or higher, being on stable doses of opioids at baseline evaluation, having had the condition for 6+ weeks, a prognosis greater than 6 months and ability to take oral medication."
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