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Sweet non-menthol, nicotine 36mg/ml for Nicotine Addiction

Phase 1
Waitlist Available
Led By Suchitra Krishnan-Sarin, PhD
Research Sponsored by Yale University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at baseline (+0 minutes), following administration of e-cigarette condition 1 (+10 minutes), following administration of e-cigarette condition 2 (+40)
Awards & highlights

Study Summary

This trial looks at how sweet and cooling flavors in e-cigarettes make them more appealing to kids, and if this increases the potential for nicotine abuse.

Eligible Conditions
  • Nicotine Addiction

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at baseline (+0 minutes), following administration of e-cigarette condition 1 (+10 minutes), following administration of e-cigarette condition 2 (+40)
This trial's timeline: 3 weeks for screening, Varies for treatment, and at baseline (+0 minutes), following administration of e-cigarette condition 1 (+10 minutes), following administration of e-cigarette condition 2 (+40) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Craving: change in craving score for e-cigarette
Irritation/Harshness: Difference score in irritation of harshness of each e-cigarette condition
Liking: Difference score in liking/wanting of each e-cigarette condition
+1 more
Other outcome measures
Exploratory Aim: Change in e-cigarette use 1 month after study procedures

Trial Design

2Treatment groups
Experimental Treatment
Group I: Sweet non-menthol, nicotine 36mg/mlExperimental Treatment2 Interventions
Sweet flavor non-menthol (Watermelon) with 36mg/ml Nicotine
Group II: Sweet menthol, nicotine 36mg/mlExperimental Treatment2 Interventions
Sweet flavor with menthol (Watermelon-menthol) with 36mg/ml Nicotine
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Flavoring Agents
2022
Completed Phase 1
~40
Nicotine
2005
Completed Phase 4
~2980

Find a Location

Who is running the clinical trial?

National Institute on Drug Abuse (NIDA)NIH
2,470 Previous Clinical Trials
2,619,691 Total Patients Enrolled
15 Trials studying Nicotine Addiction
2,130 Patients Enrolled for Nicotine Addiction
Yale UniversityLead Sponsor
1,853 Previous Clinical Trials
2,738,521 Total Patients Enrolled
4 Trials studying Nicotine Addiction
194 Patients Enrolled for Nicotine Addiction
Suchitra Krishnan-Sarin, PhDPrincipal InvestigatorYale University
4 Previous Clinical Trials
230 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any recruitments being taken for this research experiment?

"Per information available on clinicaltrials.gov, this study is not currently recruiting patients; the trial was initially posted November 1st 2022 and last revised October 19th 2022. Despite its inactivity presently, there are a total of 181 other medical trials accepting applicants right now."

Answered by AI

Who is eligible to partake in this medical investigation?

"This research requires a total of 40 volunteers between the ages 16-20 who have nicotine use disorder. Additionally, participants must be literate and within their lifetime, experimental e-cigarette usage should not exceed 10 times with no recent (past month) utilization."

Answered by AI

How many test subjects have been recruited for this research project?

"At present, this clinical trial is closed to new participants. The research initiative was posted on November 1st 2022 and the details were last updated on October 19th 2022. On the other hand, there are presently 110 trials accepting candidates with nicotine use disorder and 71 studies that study Nicotine 3 mg & Tobacco menthol admitting patients."

Answered by AI

Has the FDA sanctioned Nicotine 3 mg, Tobacco menthol?

"Based on the current level of clinical research, our experts at Power judiciously rated Nicotine 3 mg, Tobacco menthol's safety a 1. This is due to this medication being in its first phase trial and having limited data pertaining to both efficacy and security."

Answered by AI

Are there any previous investigations that have centered around Nicotine 3 mg and Tobacco menthol?

"At the moment, there are 71 clinical trials for Nicotine 3 mg, Tobacco menthol in process with 5 of them being stage 3. Most of these experiments take place at locations situated around Green Bay, Wisconsin - but that number totals to 204 distinct sites worldwide."

Answered by AI

Are applicants aged 45 and over able to enroll in this scientific research?

"To be eligible for this trial, patients must fall between the ages of 16 to 20. Conversely, 8 studies are available for those younger than 18 while 131 trials exist specifically catered towards individuals over the age of 65."

Answered by AI
~16 spots leftby May 2025