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Menthol for Smoking/Cigarette Smoking (PRISM Trial)

N/A

Waitlist Available

Led By Amy Cohn, PhD

Research Sponsored by University of Oklahoma

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6-month follow-up (6-months post-baseline)

Awards & highlights

PRISM Trial Summary

This trial looks at the effects of menthol and non-menthol cigarettes on young adults who have started smoking in the past six months.

PRISM Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6-month follow-up (6-months post-baseline)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6-month follow-up (6-months post-baseline)

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6-month follow-up (6-months post-baseline) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Between-day subjective response to smoking

Nicotine dependence

Past 30-day cigarette smoking frequency

+4 more

Secondary outcome measures

Cigarettes per day

Daily ratings of craving intensity

Smoke

+9 more

PRISM Trial Design

2Treatment groups

Experimental Treatment

Group I: Non-mentholExperimental Treatment1 Intervention

Participants will smoke and rate several puffs of a non-menthol Camel Crush cigarette

Group II: MentholExperimental Treatment1 Intervention

Participants will smoke and rate several puffs of a menthol Camel Crush cigarette

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of OklahomaLead Sponsor

455 Previous Clinical Trials

97,420 Total Patients Enrolled

Amy Cohn, PhDPrincipal Investigator - University of Oklahoma

University of Oklahoma

1 Previous Clinical Trials

260 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What aims are being sought through this clinical investigation?

"This research project aims to measure the immediate subjective response from smoking cigarettes. Secondary outcomes include metrics such as the number of clicks for menthol versus non-menthol cigarettes, quantity of tobacco product use in the past 30 days, and puff topography (total inhalation volume)."

Answered by AI

Are participants of this experiment restricted to adults eighteen years and older?

"This medical trial is searching for individuals who are between 18 and 26 years of age."

Answered by AI

How many participants have been selected for this research endeavor?

"Affirmative. The clinical trial, posted on August 1st 2020 and most recently updated April 11th 2022 is currently engaging potential participants. This study aims to recruit 250 individuals from two different sites."

Answered by AI

What criteria do individuals need to meet in order to participate in this clinical research?

"To qualify for this trial, prospective participants must be habituated to smoking cigarettes and have ages that fall between 18 and 26 years old. Currently, the clinical team is looking to enrol approximately 250 individuals in total."

Answered by AI

Is enrollment currently available for this experiment?

"According to clinicaltrials.gov, this medical investigation is presently in the recruitment stage and has been open since August 1st 2020 with its last amendment being made on April 11th 2022."

Answered by AI

Recent research and studies

BMJ OpenJournal

Measuring Young Adult Appeal for Menthol and Non-menthol Cigarettes: Protocol of a Clinical Trial Using Both Laboratory and Intensive Longitudinal Methods (PRISM)

Cohn, Amy M, Wallace Pickworth, Janet Audrain-McGovern, James Murphy, Andrea C Villanti, Donald Hedeker, Delaney Dunn, et al.. 2022. “Measuring Young Adult Appeal for Menthol and Non-menthol Cigarettes: Protocol of a Clinical Trial Using Both Laboratory and Intensive Longitudinal Methods (PRISM)”. BMJ Open. BMJ. doi:10.1136/bmjopen-2021-058823.

clinicaltrials.govStudy

Perceptions of Cigarette Smoking in Young Adults

Amy Cohn 2020. "Perceptions of Cigarette Smoking in Young Adults". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03953508.