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Menthol cigarette for Cancer

N/A

Recruiting

Led By Alayna P Tackett, PhD

Research Sponsored by Ohio State University Comprehensive Cancer Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Aged 21 - 29 years

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to end of study, estimated 1 year

Awards & highlights

Study Summary

This trial aims to study the effects of synthetic cooling agents in cigarettes on people's perception and usage of smoking. Menthol, a natural substance, is a cooling agent that makes smokers more dependent on nicotine

Who is the study for?

This trial is for adults aged 21-29 who regularly smoke cigarettes and can read and speak English. They must be willing to give informed consent and avoid tobacco products for 12 hours before lab sessions. Smokers with recent COVID-19, heart issues, serious psychiatric conditions, pregnancy or breastfeeding, attempts to quit smoking, or recent lung diseases are excluded.Check my eligibility

What is being tested?

The study examines the effects of synthetic cooling agents in cigarettes on smokers' perceptions and usage compared to usual brands and menthol cigarettes. It involves spirometry tests (to measure lung function), questionnaires, and analysis of nasal lining fluids to assess respiratory impact.See study design

What are the potential side effects?

While not directly related to treatment side effects as typical clinical trials might be, participants may experience discomfort from abstaining from smoking prior to sessions or potential irritation during spirometry testing.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am between 21 and 29 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to end of study, estimated 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to end of study, estimated 1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to end of study, estimated 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Abuse Liability via Puff Topography

Cigarette Appeal

Cigarette Chemical Contents

+1 more

Trial Design

3Treatment groups

Active Control

Group I: Menthol cigaretteActive Control5 Interventions

Participants participate in an ad libitum smoking session with a menthol cigarette for this condition. Participants also participate in an ad libitum smoking session with either their usual brand cigarette or the menthol study cigarette at the end of each study visit.

Group II: Non-menthol cigaretteActive Control5 Interventions

Participants participate in an ad libitum smoking session with a non-menthol control cigarette for this condition. Participants also participate in an ad libitum smoking session with either their usual brand cigarette or the non-menthol study cigarette at the end of each study visit.

Group III: Cigarette with synthetic cooling agentsActive Control5 Interventions

Participants participate in an ad libitum smoking session with a synthetic cooling agent cigarette for this condition. Participants also participate in an ad libitum smoking session with either their usual brand cigarette or the synthetic cooling agent study cigarette at the end of each study visit.

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

Ohio State University Comprehensive Cancer CenterLead Sponsor

320 Previous Clinical Trials

290,070 Total Patients Enrolled

Alayna P Tackett, PhDPrincipal InvestigatorOhio State University Comprehensive Cancer Center

2 Previous Clinical Trials

600 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Which individuals meet the eligibility criteria to participate in this scientific experiment?

"To be considered eligible for participation in this clinical trial, patients must have a confirmed diagnosis of cancer and fall within the age range of 21 to 29 years. The study aims to enroll approximately 25 individuals into the trial."

Answered by AI

Are patients currently able to participate in this ongoing trial?

"Affirmative. The data provided on clinicaltrials.gov states that this investigation is presently in need of participants. Originally posted on November 28, 2023, the trial was most recently updated on January 18, 2024. A total of 25 individuals are being sought from a single medical site."

Answered by AI

Is there an age restriction for potential participants in this medical study, specifically concerning individuals above the age of 30?

"Individuals in the age range of 21 to 29 years are eligible for enrollment in this clinical trial."

Answered by AI

What is the upper limit for the number of participants involved in this research endeavor?

"Indeed, according to the information provided on clinicaltrials.gov, this study is currently in active search of eligible participants. The trial was initially posted on November 28th, 2023 and last modified on January 18th, 2024. To meet its objectives, the study aims to enroll a total of 25 patients from one single site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Evaluating the Impact of Synthetic Cooling Agents in Combustible Cigarettes on Smoking Perceptions and Use

Alayna Tackett 2023. "Evaluating the Impact of Synthetic Cooling Agents in Combustible Cigarettes on Smoking Perceptions and Use". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06230159.