E-liquid Standards for Vaping Appeal

Overseen By The Ohio State Comprehensive Cancer Center

Age: 18 - 65

Sex: Any

Trial Phase: Academic

Sponsor: Ohio State University Comprehensive Cancer Center

Disqualifiers: Pregnancy, Lung disease, Cardiovascular, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

Duration: Single session up to 3 hours

150 Participants Needed

Trial Summary

What is the purpose of this trial?

The Sweet Spot Study aims to evaluate the effect of e-liquids with nicotine varying in freebase (FB) levels and concentrations on the appeal of electronic cigarettes (ECs) in young adult EC users with minimal/no history of smoking and older adult smokers.

Research Team

Theodore L Wagener, PhD

Principal Investigator

Ohio State University Comprehensive Cancer Center

Eligibility Criteria

This trial is for young adult e-cigarette users and older smokers who can go without any nicotine products for 12 hours before the study visit. Participants must be able to read and speak English.

Inclusion Criteria

I can avoid nicotine products for 12 hours before the study visit.

I am a young adult who uses e-cigarettes or an older adult who smokes.

Exclusion Criteria

I have been diagnosed with a lung disease.

I have new or worsening heart problems.

Currently attempting to quit nicotine products

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants evaluate the effect of e-liquids with varying nicotine levels on the appeal of electronic cigarettes

Single session up to 3 hours

1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

Treatment Details

Interventions

• Vaping study EC A
• Vaping study EC B
• Vaping study EC C
• Vaping study EC D
• Vaping study EC E
• Vaping study EC F
• Vaping study EC G
• Vaping study EC H
• Vaping study EC I
• Vaping study EC J

Trial Overview The Sweet Spot Study tests how appealing electronic cigarettes are when they have different levels of freebase nicotine. It involves trying various e-liquids labeled EC A through EC J in a controlled setting.

Participant Groups

Group I: Young adult EC users Active Control 10 Interventions

Young Adult EC users

Group II: Older adult smokers Active Control 10 Interventions

Adult smokers

Who Is Running the Clinical Trial?

Ohio State University Comprehensive Cancer Center

Lead Sponsor

Trials

350

Recruited

295,000+