Flavor for Nicotine Use Disorder

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Nicotine Use Disorder+1 More
Flavor - Drug
Eligibility
18 - 65
All Sexes
What conditions do you have?
Select

Study Summary

This trial looks at the effects of flavors when added to nicotine in e-cigarettes, in both young and old adult smokers.

Eligible Conditions
  • Nicotine Use Disorder

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Nicotine Use Disorder

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: Baseline (+10 minutes) to end of lab session (+40 minutes)

Baseline (+10 minutes) to end of lab session (+40 minutes)
Change score in liking/wanting of e-cigarette

Trial Safety

Safety Progress

1 of 3

Other trials for Nicotine Use Disorder

Trial Design

6 Treatment Groups

Hign Nicotine, strawberry
1 of 6
Low nicotine, tobacco
1 of 6
Low nicotine, menthol
1 of 6
Low nicotine, strawberry
1 of 6
High nicotine, tobacco
1 of 6
High nicotine, menthol
1 of 6
Experimental Treatment

120 Total Participants · 6 Treatment Groups

Primary Treatment: Flavor · No Placebo Group · Phase 1

Hign Nicotine, strawberryExperimental Group · 2 Interventions: Flavor, Nicotine · Intervention Types: Drug, Drug
Low nicotine, tobaccoExperimental Group · 2 Interventions: Flavor, Nicotine · Intervention Types: Drug, Drug
Low nicotine, mentholExperimental Group · 2 Interventions: Flavor, Nicotine · Intervention Types: Drug, Drug
Low nicotine, strawberryExperimental Group · 2 Interventions: Flavor, Nicotine · Intervention Types: Drug, Drug
High nicotine, tobaccoExperimental Group · 2 Interventions: Flavor, Nicotine · Intervention Types: Drug, Drug
High nicotine, mentholExperimental Group · 2 Interventions: Flavor, Nicotine · Intervention Types: Drug, Drug
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Nicotine
FDA approved

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline (+10 minutes) to end of lab session (+40 minutes)

Who is running the clinical trial?

Yale UniversityLead Sponsor
1,666 Previous Clinical Trials
21,074,670 Total Patients Enrolled
1 Trials studying Nicotine Use Disorder
40 Patients Enrolled for Nicotine Use Disorder

Eligibility Criteria

Age 18 - 65 · All Participants · 6 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
Smoking more than 10 cigarettes or cigars each day greatly increases your risk of developing lung cancer.
I'm willing to abstain from regular smoking for two weeks and only use e-cigarettes.
You have not used e-cigarettes in the past 30 days.
The age range of 18-24 years or 35-50 years.
The ability to read and write is a necessary skill for most jobs.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 12th, 2021

Last Reviewed: October 22nd, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.