Neurofeedback (from fMRI and/or EEG) for Nicotine Addiction

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Center for Cognitive Neuroscience, Durham, NCNicotine AddictionNeurofeedback (from fMRI and/or EEG) - Device
Eligibility
18 - 45
All Sexes
What conditions do you have?
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Study Summary

This trial aims to see if a non-medication intervention can increase motivation for non-drug rewards (like a favorite food) for people with and without nicotine dependence.

Eligible Conditions
  • Nicotine Addiction

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 2 Secondary · Reporting Duration: To occur following the neurofeedback session, up to 30 minutes following the session

Changes will be assessed across the task (~30 minutes) during the neurofeedback visit
Change in reward-related brain activation
Collected once during the screening visit
Dopamine availability
To occur following the neurofeedback session, up to 30 minutes following the session
Onset to smoking a cigarette

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Reward-related Brain Region Feedback
1 of 2
Noise Control
1 of 2

Experimental Treatment

Non-Treatment Group

100 Total Participants · 2 Treatment Groups

Primary Treatment: Neurofeedback (from fMRI and/or EEG) · Has Placebo Group · N/A

Reward-related Brain Region Feedback
Device
Experimental Group · 1 Intervention: Neurofeedback (from fMRI and/or EEG) · Intervention Types: Device
Noise Control
Device
ShamComparator Group · 1 Intervention: Neurofeedback (from fMRI and/or EEG) · Intervention Types: Device

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: to occur following the neurofeedback session, up to 30 minutes following the session

Who is running the clinical trial?

Brain & Behavior Research FoundationOTHER
55 Previous Clinical Trials
2,460 Total Patients Enrolled
National Institutes of Health (NIH)NIH
2,469 Previous Clinical Trials
24,580,873 Total Patients Enrolled
2 Trials studying Nicotine Addiction
280 Patients Enrolled for Nicotine Addiction
Duke UniversityLead Sponsor
2,207 Previous Clinical Trials
3,220,677 Total Patients Enrolled
2 Trials studying Nicotine Addiction
117 Patients Enrolled for Nicotine Addiction
Kathryn Dickerson, PhDPrincipal InvestigatorDuke University

Eligibility Criteria

Age 18 - 45 · All Participants · 7 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You need to be right-handed.
You are overall healthy.
Anyone, regardless of gender.
If you are a non-diabetic person, you smoke at least 5 regular cigarettes daily, according to your own statement.

Frequently Asked Questions

Is this research endeavor still recruiting participants?

"Affirmative. Clinicaltrials.gov attests that this clinical trial is actively recruiting participants, with the study initially posted on February 28th 2018 and most recently updated on January 28th 2022. Currently, 100 individuals need to be recruited from a single location for this medical research." - Anonymous Online Contributor

Unverified Answer

What is the enrollment capacity of this clinical study?

"Affirmative. According to the information from clinicaltrials.gov, this medical trial is currently in need of 100 participants across a single site. The project was first posted on February 28th 2018 and recently modified on January 28th 2022." - Anonymous Online Contributor

Unverified Answer

Who is eligible to participate in this scientific investigation?

"This trial seeks to enroll up to 100 nicotine-dependent individuals in the 18-45 age bracket." - Anonymous Online Contributor

Unverified Answer

Does the age requirement of this clinical trial include participants younger than 25?

"The trial is looking for participants aged between 18 and 45 years." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.