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Corticosteroid

Ketoconazole for Insulin Resistance

Phase < 1
Waitlist Available
Led By Peter Y Liu, MD PhD
Research Sponsored by Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 years
Awards & highlights

Study Summary

This trial is studying the effects of sleep restriction on the production of two hormones, cortisol and testosterone. The goal is to see if changing these hormones leads to insulin resistance, which is a cause of type 2 diabetes mellitus. The trial may also study the effect of sleep restriction on food intake and cravings, mood, inflammation, metabolism (including bone), and other hormones.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Insulin Sensitivity
Secondary outcome measures
Assessment of mood states.
Bone turnover panel
C-peptide glucose dose-response
+11 more
Other outcome measures
Epigenetics

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Drug and Placebo Group 1Active Control6 Interventions
Ketoconazole is taken 4 times a day Hydrocortisone is taken 3 times a day Testosterone gel is applied once a day
Group II: Placebo and Drug Group 2Placebo Group6 Interventions
Placebo pills and gel is used in place. Placebo for Ketoconazole is taken 4 times a day Placebo for Hydrocortisone is taken 3 times a day Placebo for testosterone gel is applied once a day.

Find a Location

Who is running the clinical trial?

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical CenterLead Sponsor
101 Previous Clinical Trials
46,261 Total Patients Enrolled
Peter Y Liu, MD PhDPrincipal InvestigatorLundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
1 Previous Clinical Trials

Media Library

Hydrocortisone (Corticosteroid) Clinical Trial Eligibility Overview. Trial Name: NCT02256865 — Phase < 1
Insulin Resistance Research Study Groups: Placebo and Drug Group 2, Drug and Placebo Group 1
Insulin Resistance Clinical Trial 2023: Hydrocortisone Highlights & Side Effects. Trial Name: NCT02256865 — Phase < 1
Hydrocortisone (Corticosteroid) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02256865 — Phase < 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there vacancies open to prospective participants of this research?

"At this time, the trial is not recruiting patients. It was posted on October 1st 2014 and last updated March 11th 2022. Fortunately, there are 163 other medical studies looking for individuals with insulin resistance; 95 of those trials are actively seeking participants."

Answered by AI

Have additional experiments been conducted involving this therapeutic approach?

"Currently, a total of 95 studies are actively assessing this intervention; out of these trials, 26 have entered Phase 3. In Hefei, Anhui alone there is an abundance of sites researching the treatment's efficacy and safety with 3191 locations overall taking part in related clinical trials."

Answered by AI

How many people are enrolled in the trial at maximum capacity?

"Unfortunately, this particular trial is not in its recruitment phase. It was posted on October 1st 2014 and last edited on March 11th 2022. However, there are 163 other trials currently recruiting patients with insulin resistance and 95 studies for the same treatment actively enlisting participants."

Answered by AI

To what specific conditions is this intervention typically administered?

"This particular treatment can be implemented to alleviate the symptoms of varicella-zoster virus acute retinal necrosis, vaginal candidiasis and iritis."

Answered by AI

Are geriatric individuals being accepted in this research program?

"Those seeking to partake in this trial must be aged between 22 and 45 years old."

Answered by AI

Is it likely that I would be eligible to participate in this clinical trial?

"To partake in this medical trial, potential patients must possess insulin resistance and be between 22 and 45 years old. Approximately 40 individuals are sought for the study."

Answered by AI
Recent research and studies
~4 spots leftby Apr 2025