Treatment for Glucose Metabolism Disorders
This study is evaluating whether a diet high in fat and low in carbohydrates may help treat type 2 diabetes.
See full descriptionAbout the trial for Glucose Metabolism Disorders
Treatment Groups
This trial involves 3 different treatments. Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
Eligibility
This trial is for patients born any sex aged 18 and older. There are 5 eligibility criteria to participate in this trial as listed below.
Approximate Timelines
Measurement Requirements
This trial is evaluating whether Treatment will improve 5 primary outcomes and 10 secondary outcomes in patients with Glucose Metabolism Disorders. Measurement will happen over the course of Baseline to 10 days.
Patient Q & A Section
What causes glucose metabolism disorders?
In [type 1 diabetes](https://www.withpower.com/clinical-trials/type-1-diabetes), a significant decrease of insulin sensitivity may be caused by impaired beta-cell function. Diabetes-related factors affect beta-cell metabolism and impair beta-cell function. This impairment of insulin action and/or secretion is in turn associated with chronic hyperglycemia.
What are the signs of glucose metabolism disorders?
The high prevalence of glucose metabolism disorders was confirmed. A high prevalence of prediabetes was found, and the risk for developing diabetes was also high. Findings from a recent study of this study imply the need to intensify an earlier screening of glucose metabolism disorders by combining blood sugar levels and oral glucose tolerance test.
Can glucose metabolism disorders be cured?
It was not demonstrated whether the improved metabolic control will be maintained and the adverse events will be significantly reduced if the diabetes is cured. In a recent study, findings need to be further confirmed for the more common type of diabetes.
What is glucose metabolism disorders?
Diabetes mellitus (DM) is a metabolic disorder that arises from a body's inability to adequately utilize or store the glucose in the blood. DM affects about 7% of people in the USA.
How many people get glucose metabolism disorders a year in the United States?
About 11.5 million people have at least one type of glucose metabolism disorder and about 60% of these have two or more type. This prevalence may be rising as rates of obesity and diabetes continue. Patients with diabetes should be tested if they have any of the associated glucose metabolism disorders. These data provide a snapshot of this important disorder.
What are common treatments for glucose metabolism disorders?
It is important to use more effective medications when diabetic patients develop hypoglycaemic crises due to prolonged fasting. In some cases, treatment may be changed to avoid the potential complications (hypoglycaemia) of hypoglycemia.
Have there been other clinical trials involving treatment?
The majority of patients with T2DM had never participated in a treatment trial. Therefore they have not had the benefit of treatment. However, it is possible they are now benefiting from some other approach to medical care that has not yet been thoroughly explored in a rigorous clinical trial.
Does glucose metabolism disorders run in families?
We found a strong statistical (P = 0.02) association between the risk of T1DM and T2DM with FPG levels (P = 0.023). We also found a significant relationship to the age of diagnosis of T2DM (P = 0.015) as well as T2DM related to the FPG levels (P = 0.011). We found that the mean age of diagnosis of T1DM was earlier in the FPG range (FPG = 6.0-6.9 mmol/l) (P = 0.007). We also found a significant association between the FPG levels and the HbA1c levels (P = 0.012).
What are the latest developments in treatment for therapeutic use?
The recent advances in research show the potential of using a combination of drugs to treat and prevent diseases effectively. New therapies allow the treatments to be prescribed as necessary in order to treat or prevent many types of diseases. The recent innovations of nanomedicine allowed for much more drug to be introduced in a less aggressive manner. In the future, these developments in nanomedicine will help to help treat many types of diseases that have been around for decades. Some of the latest therapies are discussed in this article including new ways in prevention and treatments of cancer and HIV. All of these new ideas are being implemented to help improve human health in the future.
Have there been any new discoveries for treating glucose metabolism disorders?
There have been no new scientific discoveries for treating glucose metabolism disorders for the decade ending in 2008. There are still many unanswered questions about the mechanisms that underlie diabetes. If we are to understand the cause of the diseases, it is likely that we will have to find a way to prevent diabetes in the first place. Treating the disease has been disappointing so far.
Has treatment proven to be more effective than a placebo?
Given the high risk of bias (not all studies evaluated placebo comparability and many did not use all-comers/group comparison) these conclusions must await a thorough analysis of randomization procedures, quality of control and completeness of reporting in all studies. As a consequence, the present meta-analysis can be interpreted with great caution.
How serious can glucose metabolism disorders be?
GHDs are fairly common and serious, and the number of people with GHD's has continued to grow. Diabetes in GHDs occurs late in life, affecting nearly half of adults with the disease. In most cases, there is poor control of blood glucose and an increased risk of diabetes complications such as nephropathy, retinopathy, macrovascular and peripheral vascular disease and microvascular complications. In individuals with IGT, metabolic and CV disease is not common.