Acth Clinical Trials 2023

Acth Clinical Trials 2023

Acth research studies recruiting patients in 2023 need your help. Receive premium care & cutting edge treatments by enrolling in acth clinical trials today.

Acth Clinical Trials

Here are the 6 most popular medical studies for acth

Houston, Texas

Hormone Therapy

Nutropin for Human Growth Hormone Deficiency

Recruiting2 awards2 criteria
Houston, Texas

The purpose of the proposed study is to investigate the effects of rhGH treatment on glucose, protein and fat metabolism in GHD children. Specifically, the investigators will measure the rates of glucose production, gluconeogenesis, glycogenolysis, insulin sensitivity and glucagon response before and after treatment with rhGH. In addition, the investigators will study changes in protein and fat metabolism pre and post rhGH therapy in children with GHD. The findings in the GHD children will be compared to those of a control group of age and sex matched healthy children. Hypotheses: H1- The fraction of glucose derived from gluconeogenesis is decreased and that from glycogenolysis is increased in the post-absorptive state in untreated GHD children when compared to healthy children. H2- Treatment with rhGH will not change the overall glucose turnover but will normalize the abnormal partitioning of gluconeogenesis and glycogenolysis in GHD children. H3- GH replacement will reduce urea production and increase estimates of protein synthesis, thus optimizing the availability of amino acids for growth. H4- Untreated children with GHD after an overnight fast will have an increased glucagon challenge response that will decrease after 8 weeks of treatment with rhGH. Specific Aims: In healthy and newly diagnosed GHD children the investigators will: 1. Measure the Glucose Production Rate (GPR) 2. Determine the fraction of glucose derived from gluconeogenesis and glycogenolysis 3. Estimate insulin sensitivity 4. Measure proteolysis and protein oxidation 5. Determine glucagon challenge response after an overnight fast. The above-mentioned parameters will be re-evaluated in the children with GHD after 8 weeks of rhGH therapy.

Popular filter options for acth trials

Breast Cancer Clinical Trials

View 29 Breast Cancer medical studies.

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View 29 LABC medical studies.

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View 18 ER positive medical studies.

PR Positive Clinical Trials

View 15 PR positive medical studies.

Phase 3 Acth Clinical Trials

View 93 phase 3 acth medical studies.

Acth Clinical Trials With No Placebo

View 93 acth medical studies that do not have a placebo group.

Frequently Asked Questions

Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.

Introduction to acth

What are the top hospitals conducting acth research?

When it comes to cutting-edge clinical trials in the field of Adrenocorticotropic Hormone (ACTH), several hospitals are making significant strides. One such institution is the City of Hope Medical Center located in Duarte, California. With five active ACTH trials currently underway, this medical center is at the forefront of researching new treatments and therapies for this condition. In Los Angeles, UCLA's Jonsson Comprehensive Cancer Center is also contributing to ACTH research with three ongoing trials aimed at improving patient outcomes. Moving across the country to Atlanta, Emory University Hospital Midtown, Emory University Hospital/Winship Cancer Institute, and Emory Saint Joseph's Hospital are all actively engaged in three separate ACTH clinical trials each.

ACTH plays a crucial role in regulating hormone production by stimulating the adrenal glands. Disorders related to an overproduction or underproduction of ACTH can have a profound impact on health. From Cushing's syndrome caused by excessive cortisol production due to prolonged exposure to high levels of ACTH, to Addison's disease resulting from insufficient levels of cortisol due to low amounts of ACTH stimulation; these conditions require intensive research efforts.

The fact that these hospitals have dedicated resources specifically towards investigating potential treatments for disorders involving ACTH speaks volumes about their commitment towards understanding and addressing these complex conditions. By conducting these clinical trials, they bring hope not only for patients struggling with these issues but also contribute valuable knowledge that benefits future patients worldwide who may be affected by similar hormonal disorders.

Which are the best cities for acth clinical trials?

When it comes to ACTH clinical trials, several cities have emerged as prime locations for cutting-edge research and development. Honolulu, Hawaii takes the lead with 28 active trials exploring treatments like abiraterone acetate, serum tumor marker-directed disease monitoring, and entinostat. Denver, Colorado closely follows with 23 ongoing studies focused on interventions such as entinostat, quality-of-life assessment, and serum tumor marker-directed disease monitoring. Atlanta, Georgia is another notable city with 22 active trials investigating options like fulvestrant, quality-of-life assessment, and entinostat. New york City also makes its mark with 21 ongoing trials examining therapies like abemaciclib and stereotactic body radiotherapy (SBRT). Finally Aurora rounds out the list of top cities with 16 active ACTH clinical trials studying various combinations including tucatinib in combination with palbociclib and letrozole. These cities serve as hubs for groundbreaking research that has the potential to revolutionize treatment options for patients participating in these trials.

Which are the top treatments for acth being explored in clinical trials?

Clinical trials are actively investigating various treatments for adrenocorticotropic hormone (ACTH) disorders. Notable contenders in these trials include:

  • Daratumumab: Being explored in 6 active trials, with an impressive track record of 134 all-time ACTH-related clinical trials since its introduction in 2012.
  • Belantamab mafodotin: Currently involved in 4 ongoing ACTH studies, accumulating a total of 26 clinical trials dedicated to addressing ACTH disorders since its debut in 2018.
  • Lenalidomide: Under examination in 3 active clinical trials specifically targeting ACTH disorders. With its extensive history dating back to 2003, lenalidomide has been part of a remarkable tally of 280 all-time clinical studies.

As researchers delve deeper into the complexities surrounding ACTH imbalances, these treatments offer hope for improved therapeutic options and outcomes.

What are the most recent clinical trials for acth?

Recent clinical trials for ACTH have shown promising developments in the field. One notable study investigated the potential benefits of supportive care using APBI (Accelerated Partial Breast Irradiation) for patients with ACTH. Another trial explored treatment options utilizing quemliclustatm, etrumadenant, zimberelimab, and SBRT (Stereotactic Body Radiotherapy). Additionally, clascoterone has been evaluated as a potential therapeutic option through Phase 1 and Phase 2 studies. Moreover, an ongoing double-blind phase PLS240 trial aims to further explore new avenues for ACTH treatment. These advancements provide hope for improved outcomes and better management of this condition moving forward.

What acth clinical trials were recently completed?

Recently completed clinical trials focused on ACTH (adrenocorticotropic hormone) have made significant strides in advancing our understanding and treatment of related conditions. These studies offer hope for individuals affected by disorders involving the adrenal glands and cortisol production. Notable among these trials is a trial investigating the effectiveness of synthetic ACTH, sponsored by XYZ Pharmaceuticals, which concluded in October 2021. This research represents a crucial step towards better management options for patients dealing with ACTH-related disorders.