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Clinical Trials in Colorado
View paid research studies that are recruiting in Colorado. Filter by distance, duration, and inclusion criteria to find clinical trials that pay well for your time.
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AGBS
Bellaire, TX
18+
All Sexes
Recruiting
Bellaire, TX
18+
All Sexes
The objective for this clinical study is to provide FDA with clinical evidence regarding the effectiveness and safety of the AGBS + moderate intensity lifestyle modification therapy program, indwell time of the AGBS inside the stomach, and outcomes at 48 weeks.
Tasimelteon Oral Capsule, Tasimelteon Liquid Suspension
San Leandro, CA
Any Age
All Sexes
Phase 3
Recruiting
San Leandro, CA
Any Age
All Sexes
This is a multicenter, open-label study to evaluate the efficacy and safety of a daily single oral dose of tasimelteon in treating sleep disturbances in pediatric and adult participants with ASD.
PTC518
Washington, United States
18+
All Sexes
Phase 2
Recruiting
Washington, United States
18+
All Sexes
The primary goal of this study is to evaluate the safety and pharmacodynamic effects of PTC518 and placebo in participants with HD.
CFT8634
New York, NY
Any Age
All Sexes
Phase 1 & 2
Recruiting
Locally Advanced
New York, NY
Any Age
All Sexes
The purpose of this study is to characterize the safety, tolerability, pharmacokinetics, pharmacodynamics, and antitumor activity of CFT8634 in subjects with locally advanced or metastatic SMARCB1-perturbed cancers, including synovial sarcoma and SMARCB1-null tumors with unresectable or me…
BIIB122
Englewood, CO
18+
All Sexes
Phase 2
Recruiting
Englewood, CO
18+
All Sexes
In this study, researchers will learn more about a study drug called BIIB122 in participants with early-stage Parkinson's disease (PD). In this study: Participants will take 225 milligrams (mg) of BIIB122 or a placebo as tablets by mouth. A placebo looks like the study drug but has no rea…
capivasertib
Kingwood, TX
18+
Male
Phase 3
Recruiting
Metastatic
Kingwood, TX
18+
Male
This study will assess the efficacy and safety of capivasertib plus docetaxel versus placebo plus docetaxel in participants with metastatic castration resistant prostate cancer (mCRPC), all participants will receive the docetaxel with steroid therapy and receive androgen deprivation therap…
Cilta-cel
Pittsburgh, PA
18+
All Sexes
Phase 2
Recruiting
Pittsburgh, PA
18+
All Sexes
The purpose of this study is to evaluate the efficacy and safety of cilta-cel out-of-specification (OOS).
DTX301
Toronto, Canada
Any Age
All Sexes
Phase 3
Recruiting
Toronto, Canada
Any Age
All Sexes
The primary objective is to evaluate the efficacy of DTX301 on the improvement of ornithine transcarbamylase (OTC) function by maintaining safe plasma ammonia levels with removal of dietary protein restriction and alternative pathway medication.
MiniMed 780G System
Macon, GA
Any Age
All Sexes
Recruiting
Locally Advanced
Macon, GA
Any Age
All Sexes
This US study will evaluate the safety of utilizing Lyumjev® insulin lispro-aabc in the MiniMed™ 780G System in Type 1 adult and pediatric subjects in a home setting to support product and system labeling.
GNX oral suspension, TID
Houston, TX
Any Age
All Sexes
Phase 3
Recruiting
Houston, TX
Any Age
All Sexes
This is a Phase 3, global, double-blind, randomized, placebo-controlled study of adjunctive GNX treatment in children and adults with TSC-related epilepsy. The study consists of a 4-week prospective baseline phase, defined as the first 28 days following screening, followed by a double-blin…
Healthy Hearts Family Program
Loveland, CO
Any Age
All Sexes
Recruiting
Loveland, CO
Any Age
All Sexes
The purpose of this study is to evaluate the feasibility of a 6-month family-based community intervention to mitigate cardiovascular disease risk factors in Hispanic families in northern Colorado as measured through biometric screenings, body composition, physical activity, and health know…
Heat therapy
Boulder, CO
18+
All Sexes
Recruiting
Boulder, CO
18+
All Sexes
This study aims to determine the effects of ~12 weeks of repeated hot water immersion ("heat therapy") vs. thermoneutral water immersion on blood pressure and vascular function in late middle-life to older (≥50 years) adults.
Mindfulness Meditation Training
Denver, CO
18+
All Sexes
Recruiting
Denver, CO
18+
All Sexes
The primary purpose of this study is the determine whether a 15 minute Mindfulness Meditation (MM) administered at the preoperative appointment prior to primary unilateral total joint arthroplasty (TJA) results in any improvement in Pittsburg Sleep Quality Index (PSQI) score, a validated m…
Prednisone or Prednisolone
Springdale, AR
18+
Male
Phase 3
Recruiting
Metastatic
Springdale, AR
18+
Male
The purpose of this study is to learn whether adding abemaciclib to abiraterone plus prednisone prolongs the time before prostate cancer gets worse. Participation may last approximately 60 months.
CC-486
Aurora, CO
18+
All Sexes
Phase 1
Recruiting
1 Prior Treatment
Aurora, CO
18+
All Sexes
This is an open label, dose escalation Phase I single institution pilot study for relapsed and refractory AML patients using CC-486 (oral azacitidine) with venetoclax. At the completion of dose escalation and after establishment of the MTD or recommended dose of CC-486 with venetoclax, an …
Morbidity and mortality conference toolkit
Loveland, CO
18+
All Sexes
Recruiting
Loveland, CO
18+
All Sexes
Specific Aim 1: Determine impact of standardized morbidity and mortality (M&M) toolkit on provider satisfaction with, and perceived impact of, M&M conference. Specific Aim 2: Identify barriers and facilitators to toolkit implementation.
Nintedanib (Ofev®)
New York, NY
< 18
All Sexes
Phase 3
Recruiting
New York, NY
< 18
All Sexes
This study is open to children and adolescents with interstitial lung disease (ILD) that causes lung fibrosis. This is a study for people who took part in a previous study (study 1199-0337, InPedILD™) and for people who are between 6 and 17 years old and have fibrosing ILD. This study tes…
LIFT System
Englewood, CO
18+
All Sexes
Recruiting
Englewood, CO
18+
All Sexes
The LIFT Home Study is an observational, single-arm study designed to assess the safety of non-invasive electrical spinal stimulation (ARC Therapy) administered by the LIFT System to treat upper extremity functional deficits in people with chronic tetraplegia.
ReMag
Fort Collins, CO
18 - 65
All Sexes
Recruiting
Fort Collins, CO
18 - 65
All Sexes
The purpose of the proposed project is to determine if short-term dietary supplementation of magnesium will improve performance during a series of lab-based exercise tests, will favorably modify the gut-microbiota, and will augment skeletal muscle mitochondrial function.
AZD7442
Long Beach, CA
< 18
All Sexes
Phase 1
Recruiting
Long Beach, CA
< 18
All Sexes
This study will evaluate the pharmacokinetics (PK), pharmacodynamics (PD), safety, and tolerability of AZD7442 administered intramuscularly (IM) or intravenously (IV) in pediatric participants aged ≥ 29 weeks GA to < 18 years.
UBX1325
Deerfield Beach, FL
18+
All Sexes
Phase 2
Recruiting
Deerfield Beach, FL
18+
All Sexes
This study is intended to assess safety, tolerability and biological activity of a repeat IVT injection of UBX1325 in patients with wet AMD.
JBI-802
Nashville, TN
18+
All Sexes
Phase 1 & 2
Recruiting
Locally Advanced
Nashville, TN
18+
All Sexes
The purpose of this study is to determine the maximum-tolerated dose (MTD) and recommended Phase 2 dose (RP2D) of JBI-802 in patients with Advanced Solid Tumors.The efficacy of the RP2D will be evaluated in phase 2 in patients with solid tumors of neuroendocrine differentiation.
ME3183
Rogers, AR
18+
All Sexes
Phase 2
Recruiting
Rogers, AR
18+
All Sexes
The purpose of this study is to assess the efficacy and safety of ME3183 administered orally for moderate to severe plaque psoriasis in adults.
NOMAC-E2 COC
Idaho Falls, ID
< 65
Female
Phase 3
Recruiting
Idaho Falls, ID
< 65
Female
The purpose of this study is evaluating Contraceptive Efficacy and Safety of NOMAC-E2 Combined Oral Contraceptive in Premenopausal Females Aged 14 to 35 Years (Inclusive).
CV2CoV (16 µg)
Little Rock, AR
18+
All Sexes
Phase 1
Recruiting
Little Rock, AR
18+
All Sexes
Prevention of COVID-19 caused by SARS-CoV-2.
Tirzepatide Dose 1
Wilmington, DE
< 65
All Sexes
Phase 3
Recruiting
Wilmington, DE
< 65
All Sexes
The purpose of this study is to learn more about the safety and efficacy of tirzepatide compared to placebo in children or teenagers with type 2 diabetes taking metformin, or basal insulin, or both. The overall study will last about 60 weeks with up to 14 clinic visits and 6 phone visits.…
KVD900 300 mg
Santa Monica, CA
Any Age
All Sexes
Phase 3
Recruiting
Santa Monica, CA
Any Age
All Sexes
This study is a randomized, double-blind, placebo-controlled, phase III, three-way crossover clinical trial evaluating the efficacy and safety of KVD900, in the treatment of hereditary angioedema attacks in adolescent and adult Patients
BDTX-1535 Monotherapy
Fairfax, VA
18+
All Sexes
Phase 1
Recruiting
Locally Advanced
Fairfax, VA
18+
All Sexes
This is a first-in-human, open label, multicenter study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and the preliminary antitumor activity of BDTX-1535 in patients with GBM or NSCLC harboring sensitive EGFR alterations and who have disease progression following …
AGN-151586
Lynchburg, VA
18+
All Sexes
Phase 3
Recruiting
Lynchburg, VA
18+
All Sexes
Facial lines that develop from repeated facial expression, such as glabellar lines (GL), are typically treated by selectively weakening specific muscles with small quantities of botulinum toxin. The purpose of this study is to evaluate the safety of AGN-151586 over multiple repeat treatmen…
AC176
Sarasota, FL
18+
Male
Phase 1
Recruiting
Locally Advanced
Sarasota, FL
18+
Male
This clinical trial is evaluating a drug called AC176 in participants with metastatic castration resistant prostate cancer (mCRPC) who have progressed on at least two prior systemic therapies. The main goals of this study are to: Identify the recommended dose of AC176 that can be given s…
Rimiducid
San Antonio, TX
18+
All Sexes
Phase 1
Recruiting
Locally Advanced
San Antonio, TX
18+
All Sexes
A Phase 1, open label, dose escalation and expanded cohort study of P-MUC1C-ALLO1 in adult subjects with advanced or metastatic epithelial derived solid tumors, including but not limited to the tumor types listed below.
Etonogestrel implant
Aurora, CO
18 - 65
Female
Phase 4
Recruiting
Aurora, CO
18 - 65
Female
The investigators propose a single site, single arm, open label mechanism of action pharmacodynamic pilot study of etonogestrel implant insertion prior to an luteinizing hormone (LH) surge. The investigators will evaluate ovulation rates via serum levels of reproductive hormones and transv…
Pembrolizumab
Aurora, CO
18+
All Sexes
Phase 2
Recruiting
Grade I
Aurora, CO
18+
All Sexes
Patients with locally advanced unresectable or metastatic programmed cell death ligand (PD-L1) positive triple negative breast cancer (TNBC) will be treated with radiation to one-four sites of metastasis amenable to radiation (sites of disease to be selected at the discretion of the treati…
MiniMed 780G System
Greenville, NC
Any Age
All Sexes
Recruiting
Greenville, NC
Any Age
All Sexes
This global study (US, Canada, and Europe) will evaluate the safety and effectiveness of the MiniMed 780G system in type 1 adult and pediatric subjects utilizing Fiasp (insulin aspart injection) in a home setting.
Faricimab
Houston, TX
18+
All Sexes
Phase 4
Recruiting
Newly Diagnosed
Houston, TX
18+
All Sexes
This Phase 4 study is designed to investigate treatment response in treatment-naïve underrepresented patients with diabetic macular edema (DME) who are treated with faricimab. The study population will consist of participants ≥18 years of age who self-identify as Black/African American, Hi…
Fasudil (WP-0512)
Denver, CO
18+
All Sexes
Phase 2
Recruiting
Denver, CO
18+
All Sexes
A Phase 2a Open-Label Preliminary Safety, Efficacy, and Biomarker Study of WP-0512 in Patients with Amyotrophic Lateral Sclerosis (ALS)
Fulvestrant
Boston, MA
18+
All Sexes
Phase 1
Recruiting
Locally Advanced
Boston, MA
18+
All Sexes
This is an open-label, FIH study designed to evaluate the maximum tolerated dose, safety, tolerability, PK, pharmacodynamics, and preliminary antineoplastic activity of RLY-2608, in advanced solid tumor patients with a Phosphatidylinositol-4,5-bisphosphate-3 kinase, catalytic subunit alpha…
BOTOX
Philadelphia, PA
18+
All Sexes
Phase 2
Recruiting
Philadelphia, PA
18+
All Sexes
Upper limb essential tremor (UL ET) is a movement disorder characterized by postural and/or kinetic tremor. It can cause difficulty with everyday tasks such as writing, pouring, and eating, and patients also experience associated social embarrassment. This study will assess how safe and ef…
Tocilizumab
West Palm Beach, FL
18+
All Sexes
Phase 2
Recruiting
1 Prior Treatment
West Palm Beach, FL
18+
All Sexes
This study will evaluate the efficacy, safety, and pharmacokinetics of mosunetuzumab subcutaneous (SC) formulation in participants with selected B-cell malignancies (types of non-Hodgkin's lymphoma [NHL]).
Automated Insulin Delivery Settings Initialization and Adaptation Algorithm
Aurora, CO
18+
All Sexes
Recruiting
Aurora, CO
18+
All Sexes
Obtain preliminary safety and performance data on a settings initialization and adaptation algorithm used in conjunction with closed-loop control.
BFF MDI 320/9.6 μg
Denver, CO
Any Age
All Sexes
Phase 3
Recruiting
Denver, CO
Any Age
All Sexes
This is a 24 week study to evaluate the efficacy and safety of budesonide and formoterol fumarate metered dose inhaler in adults and adolescents with inadequately controlled asthma.
ZN-d5
Nashville, TN
18+
All Sexes
Phase 1 & 2
Recruiting
1 Prior Treatment
Nashville, TN
18+
All Sexes
This is a single arm, Open-Label, Phase 1/2 Study of ZN-d5 for the Treatment of Relapsed or Refractory Light Chain (AL) Amyloidosis.
Niraparib
Eugene, OR
18+
Female
Phase 1 & 2
Recruiting
1 Prior Treatment
Eugene, OR
18+
Female
This is a Phase 1/2 study to evaluate the safety, clinical activity, pharmacokinetics (PK), and pharmacodynamics (PD) of ZN-c3 in combination with niraparib in subjects with platinum-resistant ovarian cancer.
Ga-PSMA-11
Denver, CO
18+
Male
Phase 3
Recruiting
High Risk
Denver, CO
18+
Male
Patients will receive a single dose of 68Ga-PSMA-11 and undergo a PET/CT or PET/MRI imaging study.
Vonoprazan
Little Rock, AR
18+
All Sexes
Phase 3
Recruiting
Little Rock, AR
18+
All Sexes
The primary objectives of this study are to assess the efficacy of vonoprazan (10 mg and 20 mg once daily [QD]) compared to placebo (QD) in relief of heartburn over 4 weeks in participants with NERD.
Direct Peritoneal Resuscitation
Aurora, CO
18+
All Sexes
Phase 1
Recruiting
Aurora, CO
18+
All Sexes
This study is being conducted to assess the safety of Direct Peritoneal Resuscitation (DPR) in high-risk liver transplant patients. The investigators want to also identify if this method of recovery after large surgery has the same benefits in liver transplant patients as have been appreci…
Tralokinumab
Dallas, TX
Any Age
All Sexes
Phase 3
Recruiting
Dallas, TX
Any Age
All Sexes
The purpose of this trial is to evaluate the efficacy and safety of tralokinumab administered as subcutaneous (SC) injection with Device A in adults and adolescents (age 12 to 17 years) with moderate-to-severe atopic dermatitis (AD).
SGN-B7H4V
Denver, CO
18+
All Sexes
Phase 1
Recruiting
Locally Advanced
Denver, CO
18+
All Sexes
This study will test the safety of a drug called SGN-B7H4V in participants with solid tumors. It will also study the side effects of this drug. A side effect is anything a drug does to the body besides treating the disease. Participants will have cancer that has spread in the body near wh…
OptiPulse™
Homestead, FL
18+
All Sexes
Recruiting
Grade I
Homestead, FL
18+
All Sexes
The purpose of this clinical investigation is to assess the safety and performance of Compedica's OptiPulse™ and to collect subject outcome data on the treatment of diabetic foot ulcers (DFU's) versus the standard of care (SOC). OptiPulse™ is designed to enhance blood circulation in the ve…
Daily Beverage Intervention
Greeley, CO
18 - 65
All Sexes
Recruiting
Greeley, CO
18 - 65
All Sexes
Cannabidiol (CBD), a non-psychoactive hemp derivative, is an attractive therapeutic target, and is most supported by the scientific community as an antiepileptic, anxiolytic, and antipsychotic. Additionally, CBD may cause alterations in aspects of health and fitness, fatigue, stress, calmn…
Tapinarof cream, 1%
Hialeah, FL
< 18
All Sexes
Phase 2
Recruiting
Hialeah, FL
< 18
All Sexes
This is an open-label, multicenter study to evaluate the systemic exposure and safety of topical tapinarof cream, 1% under conditions of maximal use in pediatric subjects with atopic dermatitis
Fludarabine
Birmingham, AL
18+
All Sexes
Phase 1
Recruiting
1 Prior Treatment
Birmingham, AL
18+
All Sexes
This is a Phase I dose-finding study of FT576 as monotherapy and in combination with the monoclonal antibody daratumumab in multiple myeloma (MM). The study will consist of a dose-escalation stage and an expansion stage.
NYX-783
Riverside, CA
18+
All Sexes
Phase 2 & 3
Recruiting
Riverside, CA
18+
All Sexes
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of 50 mg NYX-783 Once Daily Compared to Placebo in Participants with Post-Traumatic Stress Disorder (PTSD)
AB-205
Iowa City, IA
18+
All Sexes
Phase 3
Recruiting
Iowa City, IA
18+
All Sexes
High-dose chemotherapy followed by blood stem cell transplantation is administered to lymphoma patients with an intention to cure. However, high-dose chemotherapy simultaneously causes damage to healthy tissues that frequently result in severe complications that lead to hospitalization and…
Meat based protein with added spice; Plant based protein with added spice
Aurora, CO
18+
All Sexes
Recruiting
Aurora, CO
18+
All Sexes
To evaluate whether or not high quality protein intake from a mixed meal can be increased by using culinary herbs and spices to increase flavor intensity and food item liking in older adults.
Nivolumab
Hampton, VA
18+
Male
Phase 2
Recruiting
Metastatic
Hampton, VA
18+
Male
The purpose of this study is to assess the safety, efficacy, tolerability, and toxicity of docetaxel alone, in combination with BMS-986218, or in combination with nivolumab plus BMS-986218 in men who have metastatic castration-resistant prostate cancer (mCRPC) that progressed after novel a…
Fulvestrant
Phoenix, AZ
18+
All Sexes
Phase 3
Recruiting
Locally Advanced
Phoenix, AZ
18+
All Sexes
This study will evaluate the effect of adding abemaciclib to fulvestrant for the treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer that progressed or recurred after previous treatment with a type of drug known as a CDK4/6 …
bbT369
Nashville, TN
18+
All Sexes
Phase 1 & 2
Recruiting
1 Prior Treatment
Nashville, TN
18+
All Sexes
A Phase 1/2 Study of bbT369, a dual targeting CAR T cell drug product with a gene edit, in Relapsed and/or Refractory B cell Non-Hodgkin's Lymphoma.
Informed of results from SomaSignal Cardiovascular Risk Test in Type 2 Diabetes (CVD-T2D)
Aurora, CO
18+
All Sexes
Recruiting
Aurora, CO
18+
All Sexes
The purpose of this study is to learn more about using a proteomic test called the SomaSignal Cardiovascular (CV) Risk Test in Type 2 Diabetes (CVD-T2D) to improve medical care for patients.
PTC923
Philadelphia, PA
Any Age
All Sexes
Phase 3
Recruiting
Philadelphia, PA
Any Age
All Sexes
The main purpose of this study is to evaluate the long-term safety of PTC923 in participants with phenylketonuria, and to evaluate the changes from baseline in dietary phenylalanine (Phe)/protein consumption.
BFR
Englewood, CO
Any Age
All Sexes
Recruiting
Englewood, CO
Any Age
All Sexes
The investigators plan to investigate the efficacy of blood flow restriction (BFR) therapy in post operative rehabilitation following hip arthroscopy. BFR has shown to be great at helping the recovery process. SAGA is a well-known smart training technology company, and the investigators ai…
Soticlestat
Atlanta, GA
< 65
All Sexes
Phase 3
Recruiting
Atlanta, GA
< 65
All Sexes
The main aim of the study is to learn if soticlestat, when given as an add-on therapy, reduces the number of seizures in children and adults with Dravet Syndrome (DS) or Lennox-Gastaut Syndrome (LGS). Participants will receive their standard anti-seizure therapy, plus tablets of soticlest…
PRT2527
Fairfax, VA
18+
All Sexes
Phase 1
Recruiting
Grade I
Fairfax, VA
18+
All Sexes
This is a Phase 1 dose-escalation study of PRT2527, a Cyclin-dependent Kinase 9 (CDK9) inhibitor, in patients with advanced solid tumors. The purpose of this study is to define the dosing schedule, and maximally tolerated dose to be used in subsequent development of PRT2527.
Multi-Cancer Early Detection Test
Fort Worth, TX
18+
All Sexes
Recruiting
Fort Worth, TX
18+
All Sexes
This is a prospective, multi-center interventional study of the GRAIL multi-cancer early detection (MCED) test with return of test results for participants enrolled through healthcare systems in North America. The purpose of this study is to evaluate the safety and performance of the GRAIL…
AK002
Philadelphia, PA
18+
All Sexes
Phase 2
Recruiting
Philadelphia, PA
18+
All Sexes
This is a Phase 2, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of subcutaneous lirentelimab (AK002), given monthly for 4 doses, in adult subjects with moderate-to-severe AD inadequately controlled by topical treatments.
ARD-101
Palo Alto, CA
Any Age
All Sexes
Phase 2
Recruiting
Palo Alto, CA
Any Age
All Sexes
A Phase 2, Single-Arm, Open-Label Study to Evaluate the Safety and Efficacy of ARD-101 in Patients with Prader-Willi Syndrome
Evening Exercise
Aurora, CO
18 - 65
All Sexes
Recruiting
Aurora, CO
18 - 65
All Sexes
The investigators are doing this study to learn more about how exercising at different times of the day (morning versus evening) affects body weight, sleep, eating patterns, and other factors.
3D Mapping
Aurora, CO
Any Age
All Sexes
Recruiting
Aurora, CO
Any Age
All Sexes
3D printing is emerging as a new diagnostic tool for pre-surgical planning. 3D printed models are extremely advantageous to surgeons in their preoperative planning. Handling these physical replicas engages active spatial perception skills, enabling a more comprehensive understanding of the…
donidalorsen
Colorado Springs, CO
Any Age
All Sexes
Phase 3
Recruiting
Colorado Springs, CO
Any Age
All Sexes
The purpose of this study is to evaluate the safety and efficacy of donidalorsen in participants with HAE and effect of donidalorsenon the quality and pattern of HAE attacks and their impact on quality of life (QoL).
DTX401
Salt Lake City, UT
Any Age
All Sexes
Phase 3
Recruiting
Salt Lake City, UT
Any Age
All Sexes
The primary objectives of this study are to evaluate the efficacy of DTX401 to reduce or eliminate dependence on exogenous glucose replacement therapy to maintain euglycemia and to maintain or improve the quality of glucose control.
MT-101
Nashville, TN
18+
All Sexes
Phase 1 & 2
Recruiting
1 Prior Treatment
Nashville, TN
18+
All Sexes
This is a Phase 1/2 study to test the safety, tolerability, and efficacy of the investigational agent MT-101 in patients with Peripheral T cell Lymphoma. MT-101 is made with myeloid cells collected from the patient's blood. The myeloid cells are modified and later infused back into their v…
Radium dichloride
New York, NY
18+
Male
Phase 2
Recruiting
Metastatic
New York, NY
18+
Male
Participants will either receive treatment with standard SBRT and the study drug Radium (Ra-223) dichloride, or standard SBRT alone.
Clinical Pathway Integrated into Electronic Health Record
Falls Church, VA
Any Age
All Sexes
Recruiting
Falls Church, VA
Any Age
All Sexes
The purpose of this study is to identify the optimal deimplementation strategies for an overused practice: continuous pulse oximetry monitoring of children hospitalized with bronchiolitis who are not receiving supplemental oxygen.
Facing Your Fears: ASD/ID
Aurora, CO
< 65
All Sexes
Recruiting
Aurora, CO
< 65
All Sexes
Adolescents with ASD and intellectual disability (ID) are a complex and underserved population. Approximately 50% of individuals with ASD/ID experience significant anxiety. Yet, there are very limited mental health care interventions available for this population. Addressing anxiety and bu…
Ubrogepant
Meridian, ID
< 18
All Sexes
Phase 3
Recruiting
Meridian, ID
< 18
All Sexes
This study is evaluating whether a drug can be used to treat migraine in children and adolescents.
mRNA-1345
West Jordan, UT
18+
All Sexes
Phase 2 & 3
Recruiting
West Jordan, UT
18+
All Sexes
This study is evaluating whether a vaccine can prevent a first episode of RSV-associated lower respiratory tract disease.
Ubrogepant
Papillion, NE
< 18
All Sexes
Phase 3
Recruiting
Papillion, NE
< 18
All Sexes
This study is evaluating whether a drug can help prevent migraines in children and adolescents.
Ocrelizumab
Ottawa, Canada
< 18
All Sexes
Phase 3
Recruiting
1 Prior Treatment
Ottawa, Canada
< 18
All Sexes
This study is evaluating whether ocrelizumab is safe and effective for children and adolescents with relapsing-remitting multiple sclerosis.
HC-7366
Houston, TX
18+
All Sexes
Phase 1
Recruiting
Grade I
Houston, TX
18+
All Sexes
This is a first in human, multicenter, open label, Phase 1a/b dose escalation and dose expansion study to establish the maximum tolerated dose (MTD), recommended Phase 2 dose (RP2D), and evaluate the safety and tolerability of QD oral dosing of HC 7366 in a dose escalating fashion in subje…
Pilocarpine Ophthalmic Topical Cream, Dose 3
Cranberry Township, PA
18+
All Sexes
Phase 2
Recruiting
Cranberry Township, PA
18+
All Sexes
This is a Multicenter, Randomized, Double-Masked, Placebo-Controlled, Parallel Group Phase 2 Trial Evaluating the Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Signs and Symptoms of Dry Eye Disease.
Oral NKT2152
Indianapolis, IN
18+
All Sexes
Phase 1 & 2
Recruiting
Locally Advanced
Indianapolis, IN
18+
All Sexes
This study is evaluating whether a drug can be used to treat kidney cancer.
NVL-520
Coral Gables, FL
Any Age
All Sexes
Phase 1 & 2
Recruiting
Locally Advanced
Coral Gables, FL
Any Age
All Sexes
This study is evaluating whether a drug called NVL-520 can help treat patients with advanced ROS1-positive NSCLC.