This trial is evaluating whether Baby Foods - Plant will improve 5 primary outcomes and 9 secondary outcomes in patients with Gut Microbiomes. Measurement will happen over the course of Over 6 months.
This trial requires 300 total participants across 4 different treatment groups
This trial involves 4 different treatments. Baby Foods - Plant is the primary treatment being studied. Participants will be divided into 3 treatment groups. Some patients will receive a placebo treatment. The treatments being tested are not being studied for commercial purposes.
"The gut microbiome is highly plastic. Despite the presence of efficient treatments, the dynamics of most gut microbial species are difficult to modulate. This may be one factor limiting treatment outcomes." - Anonymous Online Contributor
"The gut microbiome is the first cellular interface between the host and the external environment and it can have an enormous impact on host fitness. To better understand and treat disease, we need a clearer understanding of what impacts the microbiome and when, how, and why it does so. This is especially important when considering the role of the gut microbiome in human health, disease and drug response." - Anonymous Online Contributor
"The treatment of gut microbiomes differs across different diseases and locations of the gut. Clinician-oriented treatments and drugs that target specific bacterial or bacterial-host-target interactions may help to improve human health." - Anonymous Online Contributor
"The proportion of individuals in the United States getting gut microbiomes is likely much higher than what we found in Germany, where we studied 10,000 samples. There is a high percentage of individuals with normal-appearing small and large intestine microbiome profiles, and these profiles could not be separated by socioeconomic status or geographic location. The low proportion of individuals with known risk factors for gut microbiome disorders (diabetes, obesity) suggests that these risk factors are not the main drivers of the normal-appearing profiles." - Anonymous Online Contributor
"The composition of the gut microbiome can be changed by lifestyle, drugs (e.g. antibiotics), and diseases (e.g. diabetes). A better understanding of these interactions could lead to improvements in treatment of diseases, such as obesity and diabetes." - Anonymous Online Contributor
"Findings from a recent study suggests that a combination of diet and the microbiomes influence each other. Furthermore, this study is the first of its kind to demonstrate that the microbiome and diet influence the immune system." - Anonymous Online Contributor
"Gut microbiota-based therapy may help modulate the imbalance of gut microbiota and regulate immune function. The development of strategies to activate, reestablish, and modify bacterial communities may provide a new avenue for manipulation of inflammatory diseases." - Anonymous Online Contributor
"The infant diet has a profound impact on gut microbiota, and these changes are likely to have a profound impact on later immune competence. In a recent study, findings suggest that it may be possible to modulate early infant colonisation by nutrition to create an appropriate adult microbiota, thereby lowering the risk of a number of complex human diseases." - Anonymous Online Contributor
"Differences in gut microbiomes between monozygotic and dizygotic twins were minimal, suggesting that most of the variation in bacterial composition is genetically determined rather than environmental. No specific bacterial genera appeared more common in monozygotic twins (of either sex), suggesting that genetic factors influence the gut microbiome as well as environmental factors. Future studies are needed to address the role of gut microbiota in the physiology and pathology of inflammatory bowel disease." - Anonymous Online Contributor
"The GF baby group had more favourable GI and mood outcomes than the BF baby group and those without GFs, over a four-month period. GFs may beneficially support a baby and its microbiome." - Anonymous Online Contributor
"We observed that about half of the plant related products marketed to babies have reported adverse reactions, mainly dermatitis. We also observed the presence of species of gut microbiota in both nonfood related samples and some food related samples. Future work will investigate the link between gut flora and gut related GI reactions to baby foods in a prospective cohort study." - Anonymous Online Contributor
"The majority of human-associated microbial species can be readily found in a healthy gut microbiome; however, most can not be reliably isolated, detected and characterized by culture methods. For species that are clinically relevant, we need new reliable and sensitive techniques for their reliable detection." - Anonymous Online Contributor