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Local Ablative Therapy for Prostate Cancer (PLATON Trial)
PLATON Trial Summary
This trial will compare the effectiveness of different treatments for prostate cancer.
PLATON Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowPLATON Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2007 Phase 4 trial • 552 Patients • NCT00110890PLATON Trial Design
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Who is running the clinical trial?
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- My prostate cancer is adenocarcinoma without any small cell cancer.My prostate cancer has spread to pelvic lymph nodes only and hasn't been treated before.I started or will start Zoladex within 12 weeks around my trial entry.My cancer is stage IV with 5 or fewer metastases.My cancer has spread to 3 or fewer places in my body, not including bones.My prostate cancer is adenocarcinoma without any small cell cancer.My prostate cancer and any spread can be treated with surgery or radiation.I am fully active or can carry out light work.I am a man who can father children and agree to use effective birth control during the study.I am a man who can father children and agree to use effective birth control during the study.I stopped my hormone therapy for cancer more than a year ago and it lasted less than 3 years.My prostate cancer is growing despite low testosterone levels.I am medically cleared by doctors for the study treatments.I agree to provide a sample of my tumor for study.I can attend all treatments and follow-ups for the study.I am fully active or can carry out light work.My prostate cancer and any spread can be treated with surgery or radiation.I can and will complete questionnaires in English or French.My cancer cannot be treated by targeting just the affected areas.My cancer has spread to the brain.I have another cancer, but it won't affect this treatment's safety or results.I started or will start Zoladex within 12 weeks around my trial entry.I can attend all treatments and follow-ups for the study.I am 18 years old or older.I have had treatment for my cancer that has returned or spread.I am medically cleared by doctors for the study treatments.My treatment for cancer spread starts within 6 weeks after being chosen for the trial.My cancer is stage IV with 5 or fewer spread sites.I agree to provide a sample of my tumor for study, and my doctor can get it.I can and will complete questionnaires in English or French.I have another cancer, but it won't affect this treatment's safety or results.I am 18 years old or older.I will start treatment targeting cancer spread within 6 weeks after being chosen for the trial.I have 3 or fewer cancer spots in organs other than bones.
- Group 1: Arm 2 (standard systemic therapy + ablative therapy))
- Group 2: Arm 1 (standard of care)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Could you provide a list of the healthcare facilities that are currently running this clinical trial within state boundaries?
"This research trial involves the participation of 15 clinical sites, such as Algoma District Cancer Program in Sault Ste. Marie, Ottawa Hospital Research Institute in Ottawa and Health Sciences North in Sudbury; all other locations are listed online."
What is the current sample size of this investigation?
"TerSera Therapeutics LLC, the body overseeing the trial, requires 410 participants that match their criteria to run it. Two of these sites are Algoma District Cancer Program in Sault Ste. Marie, Ontario and Ottawa Hospital Research Institute in Ottawa, Quebec."
Does this scientific research presently seek participants?
"Affirmative. According to information on clinicaltrials.gov, the medical trial opened for recruitment on April 18th 2019 and is currently accepting participants. The study aims to admit 410 patients from 15 distinct locations."
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