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1 for Depression

Phase 4
Waitlist Available
Led By Uma Rao, MD
Research Sponsored by Uma Rao
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Diagnosis of major depressive disorder and/or dysthymic disorder
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up measured at week 8 and month 6 post-treatment
Awards & highlights

Study Summary

This study will determine whether there are age-related differences in the body systems controlling sleep and stress hormone patterns. This study will also determine whether the differences in sleep and hormone patterns between depressed adolescents and adults are associated with differences in their response to antidepressant treatment.

Eligible Conditions
  • Depression

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~measured at week 8 and month 6 post-treatment
This trial's timeline: 3 weeks for screening, Varies for treatment, and measured at week 8 and month 6 post-treatment for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Reduction in depressive symptoms
Secondary outcome measures
Improvement in quality of life

Trial Design

1Treatment groups
Experimental Treatment
Group I: 1Experimental Treatment1 Intervention
Participants will receive bupropion in the sleep study
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Bupropion
FDA approved

Find a Location

Who is running the clinical trial?

Uma RaoLead Sponsor
National Institute of Mental Health (NIMH)NIH
2,785 Previous Clinical Trials
2,689,626 Total Patients Enrolled
666 Trials studying Depression
251,454 Patients Enrolled for Depression
Uma Rao, MDPrincipal InvestigatorMeharry Medical Collegey
3 Previous Clinical Trials
500 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Hormone and Sleep Response to Antidepressant Treatment in Adolescents and Adults With Depression
Uma Rao 2004. "Hormone and Sleep Response to Antidepressant Treatment in Adolescents and Adults With Depression". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00106197.
All > Acth > Wellbutrin
~6 spots leftby Apr 2025
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