Low-GI Diet for Spinal Cord Injuries

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of Alabama at Birmingham, Birmingham, AL
Spinal Cord Injuries+4 More
Low-GI Diet - DietarySupplement
Eligibility
18+
All Sexes
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Study Summary

The purpose of this pilot research project is to examine the impact of a low-glycemic index (GI) diet on postprandial hypotension and glucose control in individuals with chronic spinal cord injury. The objectives are: 1) To evaluate the effect of the low-GI diet on the magnitude of postprandial systolic blood pressure drop compared to a high-GI control diet. 2)To evaluate the effect of a low-GI diet on postprandial glucose and insulin responses compared to a high-GI control diet.

Eligible Conditions

  • Spinal Cord Injuries
  • Glucose Metabolism Disorders
  • Postprandial Hypotension

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

8 Primary · 3 Secondary · Reporting Duration: In-Lab testing - Visit 2 - Day 1

Day 1
Low-GI Diet on Post-meal Systolic Blood Pressure Change- Diet A- Day 1
Day 2
Low-GI Diet on Post-meal Systolic Blood Pressure Change- Diet A- Day 2
Day 3
Low-GI Diet on Post-meal Systolic Blood Pressure Change- Diet A- Day 3
Day 1
Low-GI Diet on Post-meal Systolic Blood Pressure Change- Diet B- Day 1
Day 2
Low-GI Diet on Post-meal Systolic Blood Pressure Change- Diet B- Day 2
Day 3
Low-GI Diet on Post-meal Systolic Blood Pressure Change- Diet B- Day 3
Low-GI Diet on Postprandial Glucose Responses
Day 1
Low-GI diet on postprandial glycemia- Visit 1
Day 1
Low-GI diet on postprandial glycemia - Visit 2
Day 1
Post-meal Systolic Blood Pressure Change- Visit 1
Day 1
Post-meal Systolic Blood Pressure Change- Visit 2

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

High-GI Diet
1 of 2
Low-GI Diet
1 of 2
Active Control
Experimental Treatment

12 Total Participants · 2 Treatment Groups

Primary Treatment: Low-GI Diet · No Placebo Group · N/A

Low-GI Diet
DietarySupplement
Experimental Group · 1 Intervention: Low-GI Diet · Intervention Types: DietarySupplement
High-GI Diet
DietarySupplement
ActiveComparator Group · 1 Intervention: High-GI Diet · Intervention Types: DietarySupplement

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: in-lab testing - visit 2 - day 1

Trial Background

Jia Li, Principle Investigator
Principal Investigator
University of Alabama at Birmingham
Closest Location: University of Alabama at Birmingham · Birmingham, AL
Photo of university of alabama at birmingham  1Photo of university of alabama at birmingham  2Photo of university of alabama at birmingham  3
1991First Recorded Clinical Trial
6 TrialsResearching Spinal Cord Injuries
1066 CompletedClinical Trials

Eligibility Criteria

Age 18+ · All Participants · 1 Total Inclusion Criteria

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About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.