← Back to Search

Virus Vaccine

Shingrix Vaccine for Shingles

Phase 2

Waitlist Available

Led By Nadine Rouphael, MD

Research Sponsored by Emory University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, days 1, 7, 60, 61, 67

Awards & highlights

Study Summary

This trial is testing a new shingles vaccine to see how well it works.

Eligible Conditions

Shingles
Chickenpox

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, days 1, 7, 60, 61, 67

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, days 1, 7, 60, 61, 67

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, days 1, 7, 60, 61, 67 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in innate immune signatures

Secondary outcome measures

Change in safety of Zoster vaccine recombinant, adjuvanted

Trial Design

2Treatment groups

Experimental Treatment

Group I: Younger GroupExperimental Treatment1 Intervention

Participants between the ages of 50 to 60 years will receive two doses of Zoster vaccine recombinant, adjuvanted (Shingrix®)

Group II: Older GroupExperimental Treatment1 Intervention

Participants who are ≥70 year old will receive two doses of Zoster vaccine recombinant, adjuvanted (Shingrix®)

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Shingrix®

2019

Completed Phase 2

~40

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Emory UniversityLead Sponsor

1,638 Previous Clinical Trials

2,560,494 Total Patients Enrolled

National Institute of Allergy and Infectious Diseases (NIAID)NIH

3,269 Previous Clinical Trials

5,481,431 Total Patients Enrolled

Nadine Rouphael, MDPrincipal Investigator - Emory University

Emory University Hospital Midtown, Select Specialty Hospital-Atlanta

St Joseph'S University (Medical School)

Emory University School Of Medicine (Residency)

16 Previous Clinical Trials

865 Total Patients Enrolled

Media Library

Shingrix® (Virus Vaccine) Clinical Trial Eligibility Overview. Trial Name: NCT04047979 — Phase 2

Shingles Research Study Groups: Younger Group, Older Group

Shingles Clinical Trial 2023: Shingrix® Highlights & Side Effects. Trial Name: NCT04047979 — Phase 2

Shingrix® (Virus Vaccine) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04047979 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are people with the required medical conditions currently being accepted into this research program?

"Yes, this is an ongoing study that is still recruiting patients. The details on clinicaltrials.gov show that the trial was first posted on November 14th, 2019, and updated December 4th, 2021. They are looking for a total of 60 participants from 1 location."

Answered by AI

Has this type of research been conducted before?

"There are currently 16 live trials for Shingrix® across 92 cities and 23 countries. The initial study for Shingrix® was conducted in 2014 and sponsored by Bristol-Myers Squibb. It involved 130 participants and completed its Phase 2 drug approval stage. Since 2014, 25 studies have been conducted."

Answered by AI

Could you please list other instances in which Shingrix® has been tested?

"Currently, there are 16 Shingrix® trials underway. 4 of those are Phase 3 clinical trials. Many of the studies take places in Madison, Wisconsin; however, there are a total of 207 research sites for this medication."

Answered by AI

Has the FDA cleared Shingrix® for public use?

"Shingrix® received a score of 2 because, while there is data indicating that it is safe, none of the clinical trials thus far have demonstrated efficacy."

Answered by AI

To date, how many people have enrolled in this research project?

"The clinicaltrials.gov website shows that this trial is still recruiting patients. 60 people are needed for the study, which is taking place at a single site. The listing was created on November 14th, 2019 and last updated on December 4th, 2021."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Systems Biology of Zoster Vaccine

Nadine Rouphael 2019. "Systems Biology of Zoster Vaccine". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04047979.