N-acetylcysteine for Autism

Phase-Based Progress Estimates
Department of Psychiatry and Behavioral Sciences, Palo Alto, CAAutism+1 MoreN acetyl cysteine - Drug
3 - 12
All Sexes
What conditions do you have?

Study Summary

This trial will examine the effects of NAC on restricted and repetitive behaviors in children with autism, using a double-blind, placebo-controlled study. Results may help explain how NAC can reduce symptom severity.

Eligible Conditions
  • Autism

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

2 Primary · 2 Secondary · Reporting Duration: Baseline and week 12

Baseline and week 12
Change in Gamma band activity at 12 weeks
Change in Glutamatergic neurometabolites at 12 weeks
Change in Restricted and Repetitive Behavior Scale Revised (RBS-R) at 12 weeks
Screening and week 12
Change in Children's Yale Brown-Obsessive Compulsive Scale for Autism Spectrum Disorder (CYBOCS-ASD) at 12 weeks

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Trial Design

2 Treatment Groups

1 of 2
1 of 2

Active Control

Non-Treatment Group

48 Total Participants · 2 Treatment Groups

Primary Treatment: N-acetylcysteine · Has Placebo Group · Phase 2 & 3

PlaceboComparator Group · 1 Intervention: Placebo · Intervention Types: Drug
ActiveComparator Group · 1 Intervention: N acetyl cysteine · Intervention Types: Drug

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: baseline and week 12

Who is running the clinical trial?

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NIH
1,841 Previous Clinical Trials
2,152,780 Total Patients Enrolled
Stanford UniversityLead Sponsor
2,184 Previous Clinical Trials
35,092,397 Total Patients Enrolled
John Hegarty, PhDPrincipal InvestigatorStanford University
2 Previous Clinical Trials
72 Total Patients Enrolled

Eligibility Criteria

Age 3 - 12 · All Participants · 8 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
Participants must be between the ages of 3 and 12 years and 11 months old.
You are in good health and your medical condition is under control.

Frequently Asked Questions

Is the participant criteria for this trial open to individuals beyond age forty?

"This medical trial stipulates that participants must have a minimum age of 3 and must not exceed the age of 12." - Anonymous Online Contributor

Unverified Answer

Who can partake in this clinical trial?

"Applicants who meet the criteria of having autism and ranging in age from 3 to 12 may participate in this medical trial. Currently, 48 patients are being accepted as part of this study." - Anonymous Online Contributor

Unverified Answer

How many participants are included in this clinical research?

"Indeed, the information posted on clinicaltrials.gov confirms that this medical trial is actively recruiting participants. The investigation was first made public on February 1st 2023 and has since been updated as of September 2nd 2023. At present, 48 patients are being enrolled from a single site." - Anonymous Online Contributor

Unverified Answer

Is this experiment actively seeking participants at the moment?

"Confirmed. According to clinicaltrials.gov, this research project is still actively seeking participants and was first posted on February 1st 2023 with its most recent update coming on the 9th of that same month. The investigators are hoping to recruit 48 individuals from a single site." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.