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Behavioural Intervention

Computerized Cognitive Rehabilitation for Multiple Sclerosis

Research Sponsored by Rutgers, The State University of New Jersey
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Diagnosis of multiple sclerosis with cognitive complaint
Be older than 18 years old
Screening 3 weeks
Treatment Varies
Follow Up 12 months
Awards & highlights

Study Summary

This trial looks at whether a home-based computer program can help improve thinking skills in adults with multiple sclerosis, compared to a placebo group who play a videogame. Patients are assessed before and after the intervention.

Who is the study for?
This trial is for adults with multiple sclerosis who feel they're having thinking or memory problems. They must be willing to participate, able to attend testing sessions, and have some trouble on initial thinking tests in English.Check my eligibility
What is being tested?
The study is looking at a home-based computer program designed to improve thinking skills in MS patients compared to a control group playing video games. Their brain function is measured before and after the treatment.See study design
What are the potential side effects?
Since one intervention is a computerized cognitive exercise and the other is a videogame (placebo), side effects are minimal but may include eye strain, headache, or fatigue from screen time.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
I have multiple sclerosis and experience cognitive issues.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Cognitive Functioning
Secondary outcome measures
Healthcare Utilization
Hospital Anxiety and Depression Scale
Multiple Sclerosis Quality of Life Inventory
+2 more
Other outcome measures
Six-minute Walk Test
Timed Up & Go Test

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: InterventionExperimental Treatment1 Intervention
Computerized Cognitive Rehabilitation
Group II: PlaceboPlacebo Group1 Intervention
Video game

Find a Location

Who is running the clinical trial?

Rutgers, The State University of New JerseyLead Sponsor
429 Previous Clinical Trials
64,152 Total Patients Enrolled
4 Trials studying Multiple Sclerosis
96 Patients Enrolled for Multiple Sclerosis
Horizon Blue Cross Blue Shield of New JerseyOTHER
3 Previous Clinical Trials
7,249 Total Patients Enrolled

Media Library

Computerized cognitive rehabilitation (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT03729713 — N/A
Multiple Sclerosis Research Study Groups: Intervention, Placebo
Multiple Sclerosis Clinical Trial 2023: Computerized cognitive rehabilitation Highlights & Side Effects. Trial Name: NCT03729713 — N/A
Computerized cognitive rehabilitation (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03729713 — N/A
Multiple Sclerosis Patient Testimony for trial: Trial Name: NCT03729713 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Do I meet the requirements to partake in this research?

"This clinical trial seeks 80 individuals with multiple sclerosis, aged 18 to 65 years old. To qualify for the study, applicants must possess a diagnosis of MS with accompanying cognitive complications."

Answered by AI

Are there any slots still available for participants in this research experiment?

"Affirmative. Clinicaltrials.gov has details on this active trial, which was initially posted in April 2021 and most recently updated in November 2022. It is currently recruiting 80 individuals from a single facility."

Answered by AI

How many participants are being accepted for the trial?

"Affirmative. Clinical trials registry indicates that this experiment, first announced on April 21st 2021, is actively recruiting volunteers. The research demands 80 participants to be recruited from a single site."

Answered by AI

Is eligibility for this experiment restricted to those over 60 years old?

"This clinical trial has set the age threshold at 18 to 65 years old. For younger patients, there are 32 other trials available and 372 for those above the upper limit of this particular study's parameters."

Answered by AI

Who else is applying?

What state do they live in?
New Jersey
North Carolina
How old are they?
18 - 65
What portion of applicants met pre-screening criteria?
Met criteria
Did not meet criteria
How many prior treatments have patients received?

Why did patients apply to this trial?

To help others learn about cognitive issues and their possible treatment.
PatientReceived 2+ prior treatments
~20 spots leftby Apr 2025