GABA for Chronic Pain

Phase-Based Progress Estimates
University of Florida, Gainesville, FLChronic PainGABA - DietarySupplement
65 - 100
All Sexes
What conditions do you have?

Study Summary

This triallooks into the effects of taking GABA to improve sleep quality & chronic pain in older adults, to better understand the related neurobiology.

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: Baseline up to 1 month

Month 1
Self-Reported Sleep Quality Scoring

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Trial Design

2 Treatment Groups

Daily Oral GABA
1 of 2
Daily Placebo
1 of 2

Experimental Treatment

Non-Treatment Group

198 Total Participants · 2 Treatment Groups

Primary Treatment: GABA · Has Placebo Group · Phase 2

Daily Oral GABA
Experimental Group · 1 Intervention: GABA · Intervention Types: DietarySupplement
Daily Placebo
PlaceboComparator Group · 1 Intervention: Placebo · Intervention Types: Drug
First Studied
Drug Approval Stage
How many patients have taken this drug

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: baseline up to 1 month

Who is running the clinical trial?

University of FloridaLead Sponsor
1,262 Previous Clinical Trials
699,312 Total Patients Enrolled
12 Trials studying Chronic Pain
2,141 Patients Enrolled for Chronic Pain
National Institute on Aging (NIA)NIH
1,448 Previous Clinical Trials
4,279,302 Total Patients Enrolled
11 Trials studying Chronic Pain
1,473 Patients Enrolled for Chronic Pain
Thorne Research Inc.Industry Sponsor
10 Previous Clinical Trials
413 Total Patients Enrolled
Yenisel Cruz-Almeida, MSPH, PhDPrincipal InvestigatorUniversity of Florida
2 Previous Clinical Trials
325 Total Patients Enrolled
1 Trials studying Chronic Pain
325 Patients Enrolled for Chronic Pain

Eligibility Criteria

Age 65 - 100 · All Participants · 1 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are at least 45 years old and have had moderate to severe pain on most days for the past 3 months, as well as poor sleep quality.