PM14 for Solid Tumors

MD Anderson Cancer Center, Houston, TX
PM14Phase 1RecruitingResearch Sponsored by PharmaMar

Study Summary

This trial is testing a new combination regimen for patients with advanced solid tumors.

Eligible Conditions
  • Advanced Solid Tumors

Eligibility Criteria

Inclusion Criteria

You will be eligible if you check “Yes” for the criteria below


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~from the date of first infusion of study treatment to the date of study termination, assessed up to 72 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and from the date of first infusion of study treatment to the date of study termination, assessed up to 72 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Overall response rate
Patients with dose limiting toxicities
Secondary outcome measures
Clinical Benefit Rate
Duration of Response
Incidence of Treatment-Emergent Adverse Events
+7 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: PM14Experimental Treatment1 Intervention
Patients will receive PM14 as an i.v. infusion in a total volume of 100 mL of 0.9% sodium chloride at the first three dose escalation levels. Thereafter, the volume of infusion can be increased to 250 mL.

Find a site

Who is running the clinical trial?

PharmaMarLead Sponsor
89 Previous Clinical Trials
11,375 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many research subjects are needed for this experiment?

"Yes, if you visit clinicaltrials.gov you'll see that this research is actively looking for test subjects. The original posting was on September 6th, 2017, and the listing was updated on May 23rd, 2020. They need a total of 150 people for the study, which will be conducted at 2 locations."

Answered by AI

What is the primary objective of this clinical trial?

"The main objective of this study is to measure the effect of the medication on patients with dose-limiting toxicities. Secondary objectives include Clinical Benefit Rate, Progression-free Survival, and Duration of Response."

Answered by AI

Does PM14 have the seal of approval from the FDA?

"PM14 falls into the Phase 1 category, which means that not much is known about its safety or efficacy. Our team at Power gives it a 1 out of 3."

Answered by AI
~21 spots leftby Sep 2024