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MedReviewRx for Overmedication

N/A
Waitlist Available
Led By Emily McDonald, MD
Research Sponsored by Centre for Innovation and Research in Aging, Canada
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year
Awards & highlights

Study Summary

This trial is testing whether a software application can help reduce the number of potentially inappropriate medications (PIMs) prescribed to older adults in nursing homes in New Brunswick, Canada. The hypothesis is that using the software will lead to fewer PIMs and lower medication costs for older adults.

Eligible Conditions
  • Overmedication
  • Deprescribing
  • Adverse Drug Reactions

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Impact of MedReviewRx on the prevalence of potentially inappropriate medications (PIMs) in New Brunswick nursing homes (NBNHs).
Secondary outcome measures
Change in functional status based on interRAI activities of daily living (ADL) scores.
Number of changes from baseline in composite safety data
Number of deaths
+10 more
Other outcome measures
Cost savings
Patient and family attitudes about deprescribing

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: MedReviewRxExperimental Treatment1 Intervention
During the intervention phase, MedReviewRx will be made available to nursing homes with the understanding that it will be used to facilitate medication reviews and prescription check-ups. MedReviewRx provides clinicians with access to individualized and prioritized deprescribing information from MedSafer which: a) identifies potentially inappropriate medications (PIMs), b) explains why the medication is potentially inappropriate and c) provides instructions on how to safely stop/taper the medication.
Group II: No MedReviewRxActive Control1 Intervention
During the control phase, MedReviewRx will not be accessible to health care professionals at the nursing homes. This serves to obtain baseline deprescribing levels for each nursing home.

Find a Location

Who is running the clinical trial?

McGill University Health Centre/Research Institute of the McGill University Health CentreOTHER
446 Previous Clinical Trials
158,726 Total Patients Enrolled
Horizon Health NetworkOTHER
28 Previous Clinical Trials
13,492 Total Patients Enrolled
Missing Link TechnologiesUNKNOWN

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Diagnostic and Prognostic ResearchJournal
The Impact of the Trauma Triage App on Pre-hospital Trauma Triage: Design and Protocol of the Stepped-wedge, Cluster-randomized TESLA Trial
van der Sluijs, Rogier, Audrey A. A. Fiddelers, Job F. Waalwijk, Johannes B. Reitsma, Miranda J. Dirx, Dennis den Hartog, Silvia M. A. A. Evers, et al.. 2020. “The Impact of the Trauma Triage App on Pre-hospital Trauma Triage: Design and Protocol of the Stepped-wedge, Cluster-randomized TESLA Trial”. Diagnostic and Prognostic Research. Springer Science and Business Media LLC. doi:10.1186/s41512-020-00076-1.
Journal of the American Geriatrics SocietyJournal
The Medsafer Study: A Controlled Trial of an Electronic Decision Support Tool for Deprescribing in Acute Care
McDonald, Emily G., Peter E. Wu, Babak Rashidi, Alan J. Forster, Allen Huang, Louise Pilote, Louise Papillon‐Ferland, et al.. 2019. “The Medsafer Study: A Controlled Trial of an Electronic Decision Support Tool for Deprescribing in Acute Care”. Journal of the American Geriatrics Society. Wiley. doi:10.1111/jgs.16040.
TrialsJournal
Minimum Number of Clusters and Comparison of Analysis Methods for Cross Sectional Stepped Wedge Cluster Randomised Trials with Binary Outcomes: A Simulation Study
Barker, Daniel, Catherine D’Este, Michael J. Campbell, and Patrick McElduff. 2017. “Minimum Number of Clusters and Comparison of Analysis Methods for Cross Sectional Stepped Wedge Cluster Randomised Trials with Binary Outcomes: A Simulation Study”. Trials. Springer Science and Business Media LLC. doi:10.1186/s13063-017-1862-2.
Clinical Interventions in AgingJournal
Knowledge and Willingness of Physicians About Deprescribing Among Older Patients: A Qualitative Study
Alrasheed, Maha, Tariq Alhawassi, Alanoud Alanazi, Nouf Aloudah, Fowad Khurshid, and Mohammed Alsultan. 2018. “Knowledge and Willingness of Physicians About Deprescribing Among Older Patients: A Qualitative Study”. Clinical Interventions in Aging. Informa UK Limited. doi:10.2147/cia.s165588.
~273 spots leftby Apr 2025
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