Chokeberry (Aronia melanocarpa) juice for Inflammation

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of North Dakota School of Medicine & Health Sciences, Grand Forks, ND
Inflammation+2 More
Chokeberry (Aronia melanocarpa) juice - Other
Eligibility
18+
All Sexes
What conditions do you have?
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Study Summary

American Indian populations continue to suffer disproportionately from health problems including such nutrition-related chronic diseases as diabetes and heart disease. This research project will therefore investigate how a traditional Indigenous food called chokeberry (Aronia melanocarpa) impacts epigenetic and metabolic health in relation to resiliency markers in American Indian participants. The process of research with American Indian communities is significant in that it can inform best practices in community engagement orientations, approaches, and models in future research settings.

Eligible Conditions

  • Stress Oxidative
  • Inflammation
  • Mental Health Wellness 1

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 10 Secondary · Reporting Duration: Baseline

Baseline
Adverse Childhood Experiences (ACEs) survey (10-item version)
Historical Loss Scale
Baseline and 6 weeks
2-item Generalized Anxiety Disorder Scale (GAD)
Blood pressure
C-reactive Protein (CRP)
Connor-Davidson Resilience Scale 2-item measure (CD-RISC2)
Epigenetics
Interleukin 6 (IL-6)
Lipid panel
Patient Health Questionnaire-2 (PHQ-2)
Urinary Hydroxydeoxyguanosine (8-OHdG)

Trial Safety

Safety Progress

1 of 3

Trial Design

1 Treatment Group

Chokeberry consumption
1 of 1
Experimental Treatment

50 Total Participants · 1 Treatment Group

Primary Treatment: Chokeberry (Aronia melanocarpa) juice · No Placebo Group · N/A

Chokeberry consumption
Other
Experimental Group · 1 Intervention: Chokeberry (Aronia melanocarpa) juice · Intervention Types: Other

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline
Closest Location: University of North Dakota School of Medicine & Health Sciences · Grand Forks, ND
Photo of north dakota 1Photo of north dakota 2Photo of north dakota 3
N/AFirst Recorded Clinical Trial
1 TrialsResearching Inflammation
0 CompletedClinical Trials

Who is running the clinical trial?

USDA Grand Forks Human Nutrition Research CenterFED
52 Previous Clinical Trials
3,464 Total Patients Enrolled
Altru Health SystemOTHER
2 Previous Clinical Trials
436 Total Patients Enrolled
University of North DakotaLead Sponsor
14 Previous Clinical Trials
1,351 Total Patients Enrolled
Nicole Redvers, ND, MPHPrincipal InvestigatorUniversity of North Dakota School of Medicine & Health Sciences

Eligibility Criteria

Age 18+ · All Participants · 2 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You must be between the ages of 18-65.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.