The goal of this single-blind randomized placebo-controlled trial is to test the effects of an oral ketone supplement on appetite, cognition, metabolism, and cardiovascular function in individuals with obesity and insulin resistance. The main question[s] it aims to answer are: Does taking the ketone supplement reduce appetite and improve cognition? How does the ketone supplement alter metabolism and cardiovascular function? Participants will be asked to consume a randomly assigned ketone ester supplement or a placebo and testing will be done to see how the supplement affects the following compared to a placebo: appetite, cognition, metabolism cardiovascular function Researchers will compare individuals with obesity and insulin resistance to individuals with normal weight and no insulin resistance to see if the ketone supplement affects groups differently.
14 Primary · 7 Secondary · Reporting Duration: Baseline, 30, 45, 60, 75, 90, 105, 120 minutes post ingestion
30 Total Participants · 2 Treatment Groups
Primary Treatment: Ketone Ester · Has Placebo Group · N/A
Age 18 - 50 · All Participants · 9 Total Inclusion CriteriaMark “Yes” if the following statements are true for you: