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N/A

Endoscopy Sleeve Gastroplasty for Insulin Resistance and Obesity

N/A
Waitlist Available
Led By Elena Anna O. De Filippis, MD, PhD
Research Sponsored by Mayo Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Mostly sedentary (engaging in strenuous exercise (> 70% max HR) less than 3 times a week)
Not receiving corticosteroid therapy
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at 90 days post-intervention
Awards & highlights

Study Summary

This trial will study how eosinophils (EOS) and adipose tissue (AT) interact in people with and without obesity or insulin resistance.

Eligible Conditions
  • Insulin Resistance
  • Obesity

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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You do not engage in intense exercise more than three times a week.
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You are not taking corticosteroid medication.
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You have never had asthma, COPD, autoimmune diseases like ulcerative colitis, Crohn's disease, or certain other conditions like eosinophilic esophagitis.
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You have a body mass index (BMI) higher than 30, which means you are considered obese.
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You do not smoke cigarettes.
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You are not taking any medications that affect your blood sugar or cholesterol levels.
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Your body weight has not changed by more than 5% in the past 6 months.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at 90 days post-intervention
This trial's timeline: 3 weeks for screening, Varies for treatment, and at 90 days post-intervention for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
AT-EOS content
fat mass
weight loss
Secondary outcome measures
Adipose tissue
inflammation
insulin sensitivity

Trial Design

1Treatment groups
Experimental Treatment
Group I: Subjects with ObesityExperimental Treatment1 Intervention
Subjects will be recruited to undergo endoscopic sleeve gastroplasty. The subjects will be studied at baseline, 30, 60, 90 days after procedure

Find a Location

Who is running the clinical trial?

Mayo ClinicLead Sponsor
3,176 Previous Clinical Trials
3,758,039 Total Patients Enrolled
20 Trials studying Insulin Resistance
814 Patients Enrolled for Insulin Resistance
Elena Anna O. De Filippis, MD, PhDPrincipal InvestigatorMayo Clinic

Media Library

Endoscopy Sleeve Gastroplasty (N/A) Clinical Trial Eligibility Overview. Trial Name: NCT04898400 — N/A
Insulin Resistance Research Study Groups: Subjects with Obesity
Insulin Resistance Clinical Trial 2023: Endoscopy Sleeve Gastroplasty Highlights & Side Effects. Trial Name: NCT04898400 — N/A
Endoscopy Sleeve Gastroplasty (N/A) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04898400 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are new participants still being accepted for the trial?

"Information posted on clinicaltrials.gov suggests that this medical trial is no longer actively recruiting patients, having been initially published June 1st 2021 and last updated September 6th 2022. However, there are still 1082 other trials searching for candidates at the moment."

Answered by AI

Who else is applying?

What state do they live in?
California
Michigan
Texas
How old are they?
18 - 65
What site did they apply to?
Mayo Clinic in Arizona
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
3+
~3 spots leftby Mar 2025