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Endoscopy Sleeve Gastroplasty for Insulin Resistance and Obesity
N/A
Waitlist Available
Led By Elena Anna O. De Filippis, MD, PhD
Research Sponsored by Mayo Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Mostly sedentary (engaging in strenuous exercise (> 70% max HR) less than 3 times a week)
Not receiving corticosteroid therapy
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at 90 days post-intervention
Awards & highlights
Study Summary
This trial will study how eosinophils (EOS) and adipose tissue (AT) interact in people with and without obesity or insulin resistance.
Eligible Conditions
- Insulin Resistance
- Obesity
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
You do not engage in intense exercise more than three times a week.
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You are not taking corticosteroid medication.
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You have never had asthma, COPD, autoimmune diseases like ulcerative colitis, Crohn's disease, or certain other conditions like eosinophilic esophagitis.
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You have a body mass index (BMI) higher than 30, which means you are considered obese.
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You do not smoke cigarettes.
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You are not taking any medications that affect your blood sugar or cholesterol levels.
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Your body weight has not changed by more than 5% in the past 6 months.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ at 90 days post-intervention
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at 90 days post-intervention
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
AT-EOS content
fat mass
weight loss
Secondary outcome measures
Adipose tissue
inflammation
insulin sensitivity
Trial Design
1Treatment groups
Experimental Treatment
Group I: Subjects with ObesityExperimental Treatment1 Intervention
Subjects will be recruited to undergo endoscopic sleeve gastroplasty. The subjects will be studied at baseline, 30, 60, 90 days after procedure
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Who is running the clinical trial?
Mayo ClinicLead Sponsor
3,176 Previous Clinical Trials
3,758,039 Total Patients Enrolled
20 Trials studying Insulin Resistance
814 Patients Enrolled for Insulin Resistance
Elena Anna O. De Filippis, MD, PhDPrincipal InvestigatorMayo Clinic
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- You have a body mass index (BMI) higher than 30, which means you are very overweight.You may be a candidate for an endoscopic gastroplasty at Mayo Clinic ArizonaYour body weight has not changed by more than 5% in the past 6 months.You have a history of chronic lung disease or allergic conditions.You have a body mass index (BMI) higher than 30, which indicates being significantly overweight.You are currently taking corticosteroid medication.You do not engage in intense exercise more than three times a week.You are not taking corticosteroid medication.You have never had asthma, COPD, autoimmune diseases like ulcerative colitis, Crohn's disease, or certain other conditions like eosinophilic esophagitis.You have a body mass index (BMI) higher than 30, which means you are considered obese.You have had certain autoimmune diseases such as ulcerative colitis, Crohn's disease, or rheumatoid arthritis.Your hemoglobin A1c level is higher than 5.7%, which shows signs of insulin resistance.You do not smoke.You do not smoke cigarettes.You are not taking any medications that affect your blood sugar or cholesterol levels.You are 18 years of age or older.Your body weight has not changed by more than 5% in the past 6 months.Your body mass index (BMI) is less than 30 kg/m2.You smoke cigarettes.You are taking medication that affects your blood sugar or cholesterol levels.You have gained or lost more than 5% of your body weight in the last six months.You don't exercise intensely (like running or swimming fast) at least three times a week.You have had asthma in the past.
Research Study Groups:
This trial has the following groups:- Group 1: Subjects with Obesity
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Are new participants still being accepted for the trial?
"Information posted on clinicaltrials.gov suggests that this medical trial is no longer actively recruiting patients, having been initially published June 1st 2021 and last updated September 6th 2022. However, there are still 1082 other trials searching for candidates at the moment."
Answered by AI
Who else is applying?
What state do they live in?
California
Michigan
Texas
How old are they?
18 - 65
What site did they apply to?
Mayo Clinic in Arizona
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
3+
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