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Pegvisomant for Insulin Resistance
Study Summary
This trial is studying if blocking the effects of growth hormone in the body will help people with severe insulin resistance.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2017 Phase 4 trial • 44 Patients • NCT01701973Trial Design
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Who is running the clinical trial?
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- I haven't taken NSAIDs like aspirin or ibuprofen 2 weeks before my planned biopsy.I am willing and able to sign the consent form.I am a man who can father children and agree to use contraception during and 1 month after the study.I have a genetic variant affecting insulin or diagnosed with partial lipodystrophy.I do not have severe liver disease or extremely high triglycerides.I don't have any health issues or take medications that could interfere with the study.I am currently taking blood thinners.I am between 18 and 65 years old.I haven't changed my diabetes or cholesterol medication in the last 2 weeks.I have finished growing and gone through puberty.I haven't taken niacin or similar drugs affecting fat breakdown in the last 8 weeks.
- Group 1: 1
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is there a high incidence of adverse effects for individuals who undergo this treatment?
"Given that this is a Phase 2 trial - meaning while there is some safety data, none exists yet on efficacy - our team has given it a score of 2."
Are patients of all ages being considered for this experiment?
"The age restriction for this specific trial is that all participants must be aged between 18 and 65."
What are the prerequisites for taking part in this research?
"The eligibility requirements for this clinical trial include being insulin resistant and aged 18-65. This study needs to enroll 25 patients in total."
Are people with the required health conditions able to take part in this trial right now?
"According to the listing on clinicaltrials.gov, this study is not recruiting at present. The trial was first posted on November 23rd, 2022 and was last updated a week ago on November 17th, 2022. Although this particular study isn't looking for candidates, there are 196 other studies that are currently recruiting patients."
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