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Behavioral Intervention

Cognitive Processing Therapy for PTSD in Individuals with HIV

N/A

Recruiting

Led By Cristina Lopez, PhD

Research Sponsored by Medical University of South Carolina

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Individuals that are 18 years and older

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up approximately 18 months

Awards & highlights

Study Summary

This trial will study how well an evidence-based PTSD treatment, Cognitive Processing Therapy, works to reduce HIV transmission behavior and improve HIV outcomes.

Who is the study for?

This trial is for adults over 18 with HIV and PTSD who are linked to a Ryan White clinic in South Carolina. They must have had changes in their HIV treatment, missed appointments, or shown less than perfect adherence to antiretroviral therapy recently. Participants need an adequate score on a cognitive assessment and meet specific criteria for PTSD but can't join if they have severe mental health issues like psychosis or developmental disorders.Check my eligibility

What is being tested?

The study is testing Cognitive Processing Therapy adapted for individuals with HIV (CPT-L) against the standard Lifesteps program to see if it helps improve outcomes for those suffering from both PTSD and HIV by reducing risky behaviors that could transmit HIV.See study design

What are the potential side effects?

Since this trial involves psychological therapy rather than medication, side effects may include emotional discomfort during sessions as participants work through traumatic experiences related to their PTSD.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am 18 years old or older.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ approximately 18 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~approximately 18 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and approximately 18 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Average number of enrolled participants per month

Percent of completed participants

Percent of eligible participants

Secondary outcome measures

Mean score of PTSD symptoms

Mean score of WHOQOL-HIV BREF (World Health Organization Quality of Life- HIV )

Mean score of WHOQOL-HIV BREF (World Health Organization Quality of Life- HIV)

+1 more

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Cognitive Processing Therapy-Lifesteps (CPT-L) [Group A]Experimental Treatment2 Interventions

Group II: Lifesteps [Group B]Active Control1 Intervention

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

Medical University of South CarolinaLead Sponsor

933 Previous Clinical Trials

7,394,575 Total Patients Enrolled

National Institute of Mental Health (NIMH)NIH

2,786 Previous Clinical Trials

2,689,639 Total Patients Enrolled

Cristina Lopez, PhDPrincipal InvestigatorMedical University of South Carolina

Media Library

Cognitive Processing Therapy- Lifesteps (CPT-L) (Behavioral Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05275842 — N/A

Post-Traumatic Stress Disorder Research Study Groups: Cognitive Processing Therapy-Lifesteps (CPT-L) [Group A], Lifesteps [Group B]

Post-Traumatic Stress Disorder Clinical Trial 2023: Cognitive Processing Therapy- Lifesteps (CPT-L) Highlights & Side Effects. Trial Name: NCT05275842 — N/A

Cognitive Processing Therapy- Lifesteps (CPT-L) (Behavioral Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05275842 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the current cohort size of this research?

"Yes, indeed. On clinicaltrials.gov the study is listed as presently recruiting participants with an initial post date of July 13th and most recent edit on July 25th 2022. This trial seeks 60 individuals at a single location."

Answered by AI

Are any new recruits still being welcomed into this clinical investigation?

"Affirmative. Per clinicaltrials.gov, enrollment is ongoing for this research project which was initially posted on July 13th 2022 and most recently modified on July 25th 2022. A total of 60 individuals will be recruited from a singular medical centre."

Answered by AI

What is the fundamental purpose of this clinical experiment?

"The primary outcome of this trial, evaluated over a time frame of 18 months, will be the percentage of eligible participants. Secondary outcomes include mean scores for viral load (a measure in copies per milliliter), PTSD symptoms (measured by PCL-5 scale with 33+ being clinically significant), and WHOQOL-HIV BREF domains which score from 4 to 20 - higher indicating better quality of life."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

CPT-L to Improve Outcomes for Individuals With HIV and PTSD

Cristina Lopez 2022. "CPT-L to Improve Outcomes for Individuals With HIV and PTSD". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05275842.

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