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Cognitive Processing Therapy for PTSD

N/A

Recruiting

Led By Michael R Koenigs, PhD

Research Sponsored by University of Wisconsin, Madison

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

18 years old or older

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline (one week prior to intervention), up to 7 weeks (mid-intervention), up to 14 weeks (one week post-intervention), and up to 18 weeks (one month post-treatment)

Awards & highlights

Study Summary

This trial will study the feasibility and psychological response of Cognitive Processing Therapy (CPT) in incarcerated men and women with PTSD. The study will include 2 groups of 10 individuals in both populations (40 total; 20F/20M). It will run for up to 2 years and participants can expect to be participating for up to 22 weeks.

Who is the study for?

This trial is for incarcerated men and women aged 18 or older with PTSD who are stable on their current medication, can participate in group therapy, have a reading level of at least the 4th grade, and an IQ of 70 or higher. It's not for those already in trauma-focused treatment or with a history of psychosis.Check my eligibility

What is being tested?

The study tests Cognitive Processing Therapy (CPT) to see how feasible it is and how it affects psychological responses in male and female prisoners with PTSD. There will be separate groups for men and women participating over a period up to 22 weeks.See study design

What are the potential side effects?

While CPT doesn't typically involve medical side effects like drugs do, participants may experience emotional discomfort as they confront traumatic memories during therapy sessions.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am 18 years old or older.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline (one week prior to intervention), up to 7 weeks (mid-intervention), up to 14 weeks (one week post-intervention), and up to 18 weeks (one month post-treatment)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline (one week prior to intervention), up to 7 weeks (mid-intervention), up to 14 weeks (one week post-intervention), and up to 18 weeks (one month post-treatment)

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline (one week prior to intervention), up to 7 weeks (mid-intervention), up to 14 weeks (one week post-intervention), and up to 18 weeks (one month post-treatment) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in PTSD Checklist for DSM-5 (PCL-5) severity score

Mean scores on the CSQ-8 (client satisfaction questionnaire)

Percentage of participants that attend all 12 Cognitive Processing Therapy sessions

Secondary outcome measures

Change in score on the Beck Anxiety Inventory (BAI)

Change in score on the Beck Depression Inventory 2 (BDI-II)

Percentage of eligible individuals agreeing to participate in study

+8 more

Trial Design

1Treatment groups

Experimental Treatment

Group I: Cognitive Processing Therapy (CPT) groupExperimental Treatment1 Intervention

Arm = Cognitive Processing Therapy (CPT) Group = 4 groups of 12 (48 total; 24F/24M) receive CPT to treat PTSD

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Cognitive Processing Therapy

2016

N/A

~3400

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of Wisconsin, MadisonLead Sponsor

1,182 Previous Clinical Trials

3,167,315 Total Patients Enrolled

National Institute of Mental Health (NIMH)NIH

2,783 Previous Clinical Trials

2,689,055 Total Patients Enrolled

Michael R Koenigs, PhDPrincipal InvestigatorUniversity of Wisconsin, Madison

1 Previous Clinical Trials

80 Total Patients Enrolled

Media Library

Cognitive Processing Therapy Clinical Trial Eligibility Overview. Trial Name: NCT05168267 — N/A

Post-Traumatic Stress Disorder Research Study Groups: Cognitive Processing Therapy (CPT) group

Post-Traumatic Stress Disorder Clinical Trial 2023: Cognitive Processing Therapy Highlights & Side Effects. Trial Name: NCT05168267 — N/A

Cognitive Processing Therapy 2023 Treatment Timeline for Medical Study. Trial Name: NCT05168267 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrollment still open for this research project?

"Affirmative. Evidence on clinicaltrials.gov demonstrates that the trial, which was initially posted on June 6th 2022, is actively recruiting volunteers. The clinical study requires 40 participants to be sourced from 1 site."

Answered by AI

How many participants are being recruited for this research endeavor?

"Affirmative. The publicly available information on clinicaltrials.gov reveals that recruitment for this study, which was initially advertised on June 6th 2022, is still ongoing. A total of 40 participants need to be sourced from a single medical facility."

Answered by AI

What are the core aims of this experiment?

"The primary endpoint of this study, to be assessed within 6 weeks (concluding at the 12th session), is participant satisfaction as measured by CSQ-8 scores. Secondary objectives include gathering information on why participants discontinued their participation, measuring interest in participating and ascertaining patient eligibility for inclusion."

Answered by AI

Recent research and studies

Behavioural and Cognitive PsychotherapyJournal

Treating Multiple Incident Post-traumatic Stress Disorder (PTSD) in an Inner City London Prison: The Need for an Evidence Base

Campbell, Catherine A., Idit Albert, Manuela Jarrett, Majella Byrne, Anna Roberts, Patricia Phillip, Vyv Huddy, and Lucia Valmaggia. 2015. “Treating Multiple Incident Post-traumatic Stress Disorder (PTSD) in an Inner City London Prison: The Need for an Evidence Base”. Behavioural and Cognitive Psychotherapy. Cambridge University Press (CUP). doi:10.1017/s135246581500003x.

International Journal of Prisoner HealthJournal

‘traumatisers or Traumatised’: Trauma Experiences and Personality Characteristics of Australian Prisoners

Egeressy, Anna, Tony Butler, and Mick Hunter. 2009. “‘traumatisers or Traumatised’: Trauma Experiences and Personality Characteristics of Australian Prisoners”. International Journal of Prisoner Health. Emerald. doi:10.1080/17449200903343209.

Journal of Consulting and Clinical PsychologyJournal

A Comparison of Cognitive-processing Therapy with Prolonged Exposure and a Waiting Condition for the Treatment of Chronic Posttraumatic Stress Disorder in Female Rape Victims.

Resick, Patricia A., Pallavi Nishith, Terri L. Weaver, Millie C. Astin, and Catherine A. Feuer. 2002. “A Comparison of Cognitive-processing Therapy with Prolonged Exposure and a Waiting Condition for the Treatment of Chronic Posttraumatic Stress Disorder in Female Rape Victims.”. Journal of Consulting and Clinical Psychology. American Psychological Association (APA). doi:10.1037/0022-006x.70.4.867.

International Journal of Offender Therapy and Comparative CriminologyJournal