Cognitive Processing Therapy for Post Traumatic Stress Disorder (PTSD)

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Psychiatric Institute and Clinic, Madison, WI
Post Traumatic Stress Disorder (PTSD)
Cognitive Processing Therapy - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

Study examining the psychological response to group Cognitive Processing Therapy (CPT) in incarcerated men and women with Post-traumatic stress disorder (PTSD). The study will be conducted in male and female incarcerated populations and will include 2 groups of 10 individuals for both CPT and Therapist-facilitated Support Group in both populations (i.e., 80 participants total; 40F/40M, four CPT groups of 10 (2 Female (F)/2 Male (M)); four Therapist-facilitated Support groups of 10 (2F/2M)). The study will run for up to 2 years. Participants can expect to be participating in study for up to 22 weeks.

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Post Traumatic Stress Disorder (PTSD)

Study Objectives

1 Primary · 5 Secondary · Reporting Duration: baseline (two weeks prior to intervention), up to 3 weeks (mid-intervention), up to 8 weeks (one week post-intervention), up to 12 weeks (one month post-treatment), and up to 20 weeks (three months post-treatment)

Week 7
Ratings 1-7 by clinical supervisors on quality of session elements delivered by therapist
Ratings from 0-5 by clinical supervisors on therapist adherence to five session elements
Week 12
Change in score on the Beck Depression Inventory 2 (BDI-II)
Week 20
Change in PTSD Checklist for DSM-5 (PCL-5) severity score
Change in score on the Beck Anxiety Inventory (BAI)
Percentage of participants endorsing 2 or higher on Q9 of BDI-II

Trial Safety

Safety Progress

1 of 3

Other trials for Post Traumatic Stress Disorder (PTSD)

Trial Design

2 Treatment Groups

Cognitive Processing Therapy (CPT) group
1 of 2
Therapist-facilitated Support group
1 of 2
Experimental Treatment

80 Total Participants · 2 Treatment Groups

Primary Treatment: Cognitive Processing Therapy · No Placebo Group · N/A

Cognitive Processing Therapy (CPT) group
Behavioral
Experimental Group · 1 Intervention: Cognitive Processing Therapy · Intervention Types: Behavioral
Therapist-facilitated Support group
Behavioral
Experimental Group · 1 Intervention: Therapist-facilitated Support group · Intervention Types: Behavioral
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Cognitive Processing Therapy
2016
N/A
~2120

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline (two weeks prior to intervention), up to 3 weeks (mid-intervention), up to 8 weeks (one week post-intervention), up to 12 weeks (one month post-treatment), and up to 20 weeks (three months post-treatment)
Closest Location: Psychiatric Institute and Clinic · Madison, WI
Photo of madison 1Photo of madison 2Photo of madison 3
N/AFirst Recorded Clinical Trial
2 TrialsResearching Post Traumatic Stress Disorder (PTSD)
0 CompletedClinical Trials

Who is running the clinical trial?

Wisconsin Partnership ProgramOTHER
6 Previous Clinical Trials
307 Total Patients Enrolled
University of Wisconsin, MadisonLead Sponsor
1,052 Previous Clinical Trials
2,559,831 Total Patients Enrolled
8 Trials studying Post Traumatic Stress Disorder (PTSD)
640 Patients Enrolled for Post Traumatic Stress Disorder (PTSD)
Michael R Koenigs, PhDPrincipal InvestigatorUniversity of Wisconsin, Madison
1 Previous Clinical Trials
40 Total Patients Enrolled
1 Trials studying Post Traumatic Stress Disorder (PTSD)
40 Patients Enrolled for Post Traumatic Stress Disorder (PTSD)

Eligibility Criteria

Age 18+ · All Participants · 6 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You must be at least 18 years old.
You meet criteria for PTSD.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

References