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Behavioral Intervention

Cognitive Processing Therapy for Substance Use Disorders

N/A
Waitlist Available
Led By Melissa Zielinski, Phd
Research Sponsored by University of Arkansas
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
18 years of age or older
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up pre-treatment assessments will be completed within 4 weeks of treatment start. post-treatment assessments will be completed within 2 weeks of treatment end. post-release assessments will be completed approximately 3 months after release from prison.
Awards & highlights

Summary

This trial will study whether a specific therapy can help reduce drug use, psychiatric symptoms, and recidivism for people who have been incarcerated.

Who is the study for?
This trial is for adults over 18 who are incarcerated in Arkansas, within 9 months of release, and have a history of substance use disorder and trauma. They must understand English, consent to participate, and be able to provide contact information post-release.Check my eligibility
What is being tested?
The study tests Cognitive Processing Therapy (CPT) for treating trauma in incarcerated drug users compared to a control therapy focused on coping. It aims to see if CPT can reduce drug use, psychiatric symptoms, and recidivism.See study design
What are the potential side effects?
While the trial does not involve medication with physical side effects, participants may experience emotional discomfort or distress while discussing traumatic experiences during therapy sessions.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am 18 years old or older.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~pre-treatment assessments will be completed within 4 weeks of treatment start. post-treatment assessments will be completed within 2 weeks of treatment end. post-release assessments will be completed approximately 3 months after release from prison.
This trial's timeline: 3 weeks for screening, Varies for treatment, and pre-treatment assessments will be completed within 4 weeks of treatment start. post-treatment assessments will be completed within 2 weeks of treatment end. post-release assessments will be completed approximately 3 months after release from prison. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in PTSD Symptoms by Treatment End and 3 Months Post-Release from Incarceration
Post-Incarceration Drug Use
Secondary outcome measures
Change in Depression Symptoms by Treatment End and 3 Months Post-Release from Incarceration
Recidivism

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Cognitive Processing Therapy (CPT)Experimental Treatment1 Intervention
CPT is a gold-standard evidence-based psychotherapy for PTSD that combines education about trauma with strategies to challenge the trauma-related cognitions that are theorized to maintain PTSD symptoms. It can be delivered in group and individual formats, but will be delivered in a group format in this project due to feasibility in the setting. Structure will be based on feedback obtained during completion of Aim 2 while remaining within the range evaluated in prior research (i.e., 8-12 sessions, 1-2x per week, each lasting 1.5-2 hours).
Group II: Coping Skills GroupActive Control1 Intervention
The Coping Skills Group will match for attention and dose, without adding any cost to the system. Exact content will be determined during completion of Aim 2; however, project sites already provide coping-focused programming and coping-skill approaches to trauma treatment are a common alternative to evidence-based therapies for PTSD, such as CPT, that deal more directly with the index trauma. To provide an enhanced standard of care, the investigator will review treatment materials (workbooks, handouts) already used in prison settings and arrange a curriculum of skills similar to those in coping-focused trauma-informed interventions (e.g., psychoeducation, assertiveness).
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Cognitive Processing Therapy
2016
N/A
~3400

Find a Location

Who is running the clinical trial?

National Institute on Drug Abuse (NIDA)NIH
2,503 Previous Clinical Trials
2,625,435 Total Patients Enrolled
University of ArkansasLead Sponsor
488 Previous Clinical Trials
150,321 Total Patients Enrolled
Melissa Zielinski, PhdPrincipal InvestigatorUniversity of Arkansas

Media Library

Cognitive Processing Therapy (Behavioral Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT04007666 — N/A
Substance Use Disorder Research Study Groups: Cognitive Processing Therapy (CPT), Coping Skills Group
Substance Use Disorder Clinical Trial 2023: Cognitive Processing Therapy Highlights & Side Effects. Trial Name: NCT04007666 — N/A
Cognitive Processing Therapy (Behavioral Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04007666 — N/A
~18 spots leftby Mar 2025