Cognitive Processing Therapy for Depression

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
East Central Arkansas Community Correction Center (ECACCC), West Memphis, AR
Depression+9 More
Cognitive Processing Therapy - Behavioral
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether a treatment for trauma called Cognitive Processing Therapy (CPT) can be implemented in prisons and be effective for people who have been incarcerated.

See full description

Eligible Conditions

  • Depression
  • Substance Use Disorders (SUD)
  • Substance Abuse
  • Alcohol Abuse
  • Post Traumatic Stress Disorder (PTSD)
  • Recidivism

Treatment Effectiveness

Study Objectives

This trial is evaluating whether Cognitive Processing Therapy will improve 2 primary outcomes and 2 secondary outcomes in patients with Depression. Measurement will happen over the course of 12 months after release from incarceration.

Month 12
Recidivism
Month 3
Post-Incarceration Drug Use
Month 3
Change in Depression Symptoms by Treatment End and 3 Months Post-Release from Incarceration
Change in PTSD Symptoms by Treatment End and 3 Months Post-Release from Incarceration

Trial Safety

Trial Design

2 Treatment Groups

Coping Skills Group
1 of 2
Cognitive Processing Therapy (CPT)
1 of 2
Active Control
Experimental Treatment

This trial requires 244 total participants across 2 different treatment groups

This trial involves 2 different treatments. Cognitive Processing Therapy is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Cognitive Processing Therapy (CPT)
Behavioral
CPT is a gold-standard evidence-based psychotherapy for PTSD that combines education about trauma with strategies to challenge the trauma-related cognitions that are theorized to maintain PTSD symptoms. It can be delivered in group and individual formats, but will be delivered in a group format in this project due to feasibility in the setting. Structure will be based on feedback obtained during completion of Aim 2 while remaining within the range evaluated in prior research (i.e., 8-12 sessions, 1-2x per week, each lasting 1.5-2 hours).
Coping Skills Group
Behavioral
The Coping Skills Group will match for attention and dose, without adding any cost to the system. Exact content will be determined during completion of Aim 2; however, project sites already provide coping-focused programming and coping-skill approaches to trauma treatment are a common alternative to evidence-based therapies for PTSD, such as CPT, that deal more directly with the index trauma. To provide an enhanced standard of care, the investigator will review treatment materials (workbooks, handouts) already used in prison settings and arrange a curriculum of skills similar to those in coping-focused trauma-informed interventions (e.g., psychoeducation, assertiveness).
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Cognitive Processing Therapy
2016
N/A
~2080

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: pre-treatment assessments will be completed within 4 weeks of treatment start. post-treatment assessments will be completed within 2 weeks of treatment end. post-release assessments will be completed approximately 3 months after release from prison.
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly pre-treatment assessments will be completed within 4 weeks of treatment start. post-treatment assessments will be completed within 2 weeks of treatment end. post-release assessments will be completed approximately 3 months after release from prison. for reporting.

Closest Location

East Central Arkansas Community Correction Center (ECACCC) - West Memphis, AR

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 10 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Must not be currently incarcerated The applicant must not be currently incarcerated and must have been released from incarceration within the past nine months. show original
People who have experienced a traumatic event and are still experiencing difficulties as a result may have a history of exposure to trauma. show original
If you have a history of drug or alcohol abuse, you're more likely to end up in prison. show original
This refers to a person who is 18 years of age or older. show original
, Spanish and French She can understand and speak English, Spanish, and French. show original
Able to give informed consent
All participants must meet all the inclusion criteria. show original
The PI has invited specific people to participate in the study due to their roles at the treatment sites show original
Prisoners in Arkansas are often held in either the East Central Arkansas Community Correction Center or the Northeast Arkansas Community Correction Center. show original
Expect to reside in Arkansas throughout the study period

Patient Q&A Section

What does cognitive processing therapy usually treat?

"Cognitive processing therapy of substance abusers results in significant improvement, and appears to be successful when provided by a trained and supervised professional. When provided in group format, attendance and participation can be low, but still meaningful improvement is obtained. Cognitive processing therapy appears effective and is a promising treatment for substance abusers." - Anonymous Online Contributor

Unverified Answer

What is drug abuse?

"Drug abuse includes a diverse array of behaviors and can result in both physical and psychological repercussions. Abuse of an addictive drug is often related to other more common addictions such as tobacco or alcohol. Drug abuse is one of the leading causes of death in the United States. It is important to educate people about the various types of drugs, effects, and dangers that are associated with drug abuse. As early detection is key to preventing many cases of drug abuse, medical professionals, public health educators, and school officials all play important roles in aiding those struggling with drug abuse. Drug abuse counseling is one of the most effective and cost-efficient treatments for people suffering from addiction." - Anonymous Online Contributor

Unverified Answer

What are common treatments for drug abuse?

"The most commonly utilized types of abuse therapies are individual psychotherapy, group treatment, residential rehabilitation for drug abusers, and counseling. Other types of treatment are widely used, but the exact number is unknown." - Anonymous Online Contributor

Unverified Answer

Can drug abuse be cured?

"Drug abuse can't be cured. Some addicts may be cured from their addictions as they lose motivation to use drugs. On the other hand, drug abusers who are currently in treatment might lose interest in treatment and drug use. These people may not be cured from their addictions." - Anonymous Online Contributor

Unverified Answer

What causes drug abuse?

"Drug habits are often based on a series of habits, which leads to drug abuse. This causes depression, which causes more drug habits, which in turn cause more depression, and so on. Therefore, drug addiction has a positive feedback loop.\n" - Anonymous Online Contributor

Unverified Answer

How many people get drug abuse a year in the United States?

"On average, about 5,700 people per year in the United States will suffer from drug abuse. However, because the age distribution is skewed, the number of drug abusers is underestimated." - Anonymous Online Contributor

Unverified Answer

What are the signs of drug abuse?

"Signs of drug abuse are commonly found in people who abuse substances. A person who abuse drugs may exhibit many of these signs. These signs may include excessive sweating, increased heart rate and increased blood pressure, and/or difficulty sleeping. There may be no physical sign, such as sweating or a pounding headache.\n\n

"Acinetobacter olei\n\nAcinetobacter olei is a Gram-negative, strictly aerobic, non-spore-forming bacterium from the genus "Acinetobacter".\n"A. olei" has been isolated from compost." - Anonymous Online Contributor

Unverified Answer

What is cognitive processing therapy?

"What is CPT? Cognitive Processing Therapy (CPT) is a specific, time-limited psychotherapeutic intervention tailored to each person's unique [needs] and symptoms in order to enhance cognition and reduce psychopathology. CPT is specifically tailored to a person's mental health needs (or illness symptoms) so that it will [have a] short duration of time. CPT has a [limited] number of sessions, each lasting 90 minutes. CPT involves psychoeducation about the nature of the symptoms, and a process of coping in the present and the future. CPT does not assume a person's personality or personality type as determining factors in symptom development." - Anonymous Online Contributor

Unverified Answer

How serious can drug abuse be?

"Severe complications occur in about 1.3% of individuals involved in drug use. The risk of serious adverse consequences increases with the amount of medication taken. The likelihood of serious complications is also increased by concomitant misuse of other drugs." - Anonymous Online Contributor

Unverified Answer

How does cognitive processing therapy work?

"Cognitive processing therapy leads to reductions in posttraumatic symptoms after therapy. The reduction in posttraumatic symptoms was most strongly associated with the number of sessions that the patient attended, suggesting that attendance to the treatment is important to the effect of cognitive processing therapy on PTSD symptoms." - Anonymous Online Contributor

Unverified Answer

Is cognitive processing therapy typically used in combination with any other treatments?

"Cognitive Processing Therapy (CPT) appears to be commonly used in combination with other treatments. The evidence reviewed here is limited and inconclusive, which limits the strength of inference from the studies reviewed. However, the evidence reviewed supports CPT as an effective therapeutic option, either as a standalone treatment (when it is combined with other psychotherapies) or as part of multimodal treatment (when it is combined with CBT)." - Anonymous Online Contributor

Unverified Answer

What is the latest research for drug abuse?

"We look at current research on alcohol abuse and dependence in general, and on the prevention of alcohol abuse in particular. We also take a look at drugs other than cannabis at this point." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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