Written Exposure Therapy for Substance Use Disorder

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Substance Use Disorder+1 MoreWritten Exposure Therapy - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test the efficacy of written exposure therapy (WET) for treating posttraumatic stress disorder (PTSD) in veterans with substance use disorder (SUD) who are already engaged in SUD treatment. WET is a brief trauma-focused intervention that has been shown to be effective for treating PTSD. The goal of this study is to improve outcomes for veterans with comorbid SUD/PTSD.

Eligible Conditions
  • Substance Use Disorder
  • Post Traumatic Stress Disorder

Treatment Effectiveness

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: 12-week Post-Baseline Follow-up

12-week Post-Baseline Follow-up
PTSD Checklist for DSM-5 (PCL-5)
8-week Post-Baseline Follow-up
Timeline Follow-Back (TLFB)

Trial Safety

Trial Design

2 Treatment Groups

Neutral Topic Writing
1 of 2
Written Exposure Therapy
1 of 2

Active Control

Experimental Treatment

170 Total Participants · 2 Treatment Groups

Primary Treatment: Written Exposure Therapy · No Placebo Group · N/A

Written Exposure Therapy
Behavioral
Experimental Group · 1 Intervention: Written Exposure Therapy · Intervention Types: Behavioral
Neutral Topic Writing
Behavioral
ActiveComparator Group · 1 Intervention: Neutral Topic Writing · Intervention Types: Behavioral
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Written Exposure Therapy
2013
N/A
~200

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 12-week post-baseline follow-up

Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor
1,485 Previous Clinical Trials
2,742,049 Total Patients Enrolled
Sarah Meshberg-Cohen, PhD MS BSPrincipal InvestigatorVA Connecticut Healthcare System West Haven Campus, West Haven, CT

Eligibility Criteria

Age 18+ · All Participants · 4 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have a substance use disorder (SUD).