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Behavioral Intervention

Cognitive Processing Therapy for Post-Traumatic Stress Disorder (LIFESCAPE Trial)

N/A
Waitlist Available
Led By Annesa P Flentje, PhD
Research Sponsored by University of California, San Francisco
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up months 3, 6, and 12
Awards & highlights

LIFESCAPE Trial Summary

"This trial aims to determine if two types of therapy, Cognitive Processing Therapy and STAIR Narrative Therapy, are effective in treating posttraumatic stress disorder (PTSD) in LGBTQIA+ adults. The

Who is the study for?
This trial is for LGBTQIA+ adults with PTSD. It's looking to see if two therapies, STAIR Narrative Therapy and Cognitive Processing Therapy, can reduce PTSD symptoms and improve life quality. Participants must identify as part of the sexual or gender minority community.Check my eligibility
What is being tested?
The study compares STAIR Narrative Therapy with Cognitive Processing Therapy in treating PTSD among LGBTQIA+ individuals. It will evaluate symptom reduction, quality of life enhancement, treatment satisfaction, and completion rates within this population.See study design
What are the potential side effects?
While not explicitly listed here, common side effects from psychological therapies like these may include emotional discomfort due to discussing traumatic events, temporary increases in distress levels, and fatigue.

LIFESCAPE Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~months 3, 6, and 12
This trial's timeline: 3 weeks for screening, Varies for treatment, and months 3, 6, and 12 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Posttraumatic Stress Disorder (PTSD) Symptoms Measured by PTSD Checklist for DSM-5 (PCL-5)
Secondary outcome measures
Assessing Treatment Dropout Measured by Completion of Less than 8 Sessions
Change in Depression Measured by Patient Health Questionnaire (PHQ-9)
Change in Quality of Life Measured by WHOQOL-BREF: Social Relationships and Environment Scales
+1 more
Other outcome measures
Minority Stress Measured by Cultural Assessment of Risk for Suicide (CARS) Minority Stress Subscale - Moderator
Substance Use Measured Alcohol and Substance, Smoking, and Substance Involvement Screening Test (ASSIST) - Moderator

LIFESCAPE Trial Design

2Treatment groups
Active Control
Group I: Cognitive Processing TherapyActive Control1 Intervention
Cognitive Processing Therapy is a ~12 session trauma-focused therapy that teaches cognitive restructuring skills to help clients change beliefs and process emotions related to a specific traumatic event, which can be generalized to other traumatic experiences as well as everyday stressors. After initial psychoeducation and practice with cognitive restructuring skills, patients use skills to identify and challenge maladaptive beliefs about the traumatic event itself as well as those related to five themes thought to be affected by trauma-safety, trust, power, control, esteem, and intimacy.
Group II: STAIR Narrative TherapyActive Control1 Intervention
STAIR Narrative Therapy is a ~16-session multicomponent therapy that includes a coping skills component (10 sessions) focused on increasing skills in emotion regulation and interpersonal relationships to address day-to-day life stressors and improve functioning, and a trauma-focused component (6 sessions) which reviews a patient-selected series of traumatic experiences in which the meaning of the events is re-appraised particularly regarding sense of self and relationship to others.

Find a Location

Who is running the clinical trial?

University of California, San FranciscoLead Sponsor
2,510 Previous Clinical Trials
15,243,307 Total Patients Enrolled
Stanford UniversityOTHER
2,396 Previous Clinical Trials
17,341,155 Total Patients Enrolled
Patient-Centered Outcomes Research InstituteOTHER
552 Previous Clinical Trials
29,997,458 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are patients currently being accepted to participate in this clinical trial?

"According to information found on clinicaltrials.gov, this particular research investigation is not currently seeking participants. The trial was first registered on May 1st, 2024 and last updated on April 11th, 2024. Despite the closure of this study for recruitment purposes, there are numerous other trials actively enrolling patients - a total of 412 as per the latest data available."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
A Comparative Effectiveness Study of PTSD Treatments Among Sexual and Gender Minority Populations
2024. "A Comparative Effectiveness Study of PTSD Treatments Among Sexual and Gender Minority Populations". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06367764.
~267 spots leftby Jun 2028
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