Smoking Cessation Program for Sexual and Gender Minority Young Adults

Overseen By Tamara Stimatze

Age: 18 - 65

Sex: Any

Trial Phase: Academic

Sponsor: Fred Hutchinson Cancer Center

Must not be taking: Tobacco cessation treatments

Disqualifiers: Same household, NCI QuitGuide, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

Duration: 3 months

120 Participants Needed

Trial Summary

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications. However, you cannot be using other tobacco cessation treatments at the time of screening, but you can start them during the study.

What data supports the effectiveness of the treatment EQQUAL-NM for smoking cessation in sexual and gender minority young adults?

Research shows that culturally tailored smoking cessation programs can be effective for LGBT individuals, suggesting that treatments like EQQUAL-NM, which are designed specifically for sexual and gender minority young adults, may also be beneficial. ^{1 2 3 4 5}

How is the EQQUAL-NM treatment unique for smoking cessation in sexual and gender minority young adults?

EQQUAL-NM is unique because it is a culturally tailored digital program specifically designed for sexual and gender minority young adults, addressing their unique barriers to quitting smoking, unlike standard treatments that may not consider these specific needs. ^{1 2 5 6 7}

What is the purpose of this trial?

This clinical trial assesses the acceptability and efficacy of Empowered, Queer, Quitting, and Living--New Mexico (EQQUAL-NM), a smoking cessation intervention for sexual and gender minority young adults in New Mexico. Smoking prevalence among sexual and gender minority (SGM) adults in New Mexico is more than twice as high as non-SGM adults. Helping young adult tobacco users to quit is critical, yet there have been few efforts to develop tailored treatments specifically for this population. EQQUAL-NM is a digital smoking cessation intervention designed specifically for SGM young adult smokers in New Mexico and may help them quit smoking.

Research Team

Jaimee Heffner

Principal Investigator

Fred Hutch/University of Washington Cancer Consortium

Eligibility Criteria

This trial is for sexual and gender minority young adults in New Mexico who smoke and are interested in quitting. It's designed to help this group because they have higher smoking rates than non-SGM adults.

Inclusion Criteria

Understand and agree to the conditions of compensation

Willing and able to stream audio and video for this study

Current use of a personal email account

Exclusion Criteria

Google voice number as sole phone number

Member of the same household as another research participant

Previous use of the National Cancer Institute (NCI) QuitGuide app

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive access to a self-guided, smartphone app-delivered quit smoking program, EQQUAL-NM, with text message reminders and prompts.

3 months

Follow-up

Participants are monitored for smoking cessation outcomes and may undergo saliva sample collection.

3 months

Treatment Details

Interventions

• EQQUAL-NM

Trial Overview The EQQUAL-NM program, a smartphone app-based smoking cessation intervention tailored for SGM young adult smokers, is being tested. Participants will also provide biospecimens, answer questionnaires, and receive health education.

Participant Groups

Group I: Arm I (EQQUAL-NM, Program A) Experimental Treatment 4 Interventions

Participants receive self-guided smartphone app-delivered EQQUAL-NM (Program A) intervention on study. Participants also receive motivational messages, reminders and smoking cessation information via text messages. Some participants also complete at-home saliva sample collection during follow-up.

Group II: Arm II (EQQUAL-NM, Program B) Active Control 4 Interventions

Participants receive self-guided smartphone app-delivered EQQUAL-NM (Program B) intervention on study. Participants also receive motivational messages, reminders and smoking cessation information via text messages. Some participants also complete at-home saliva sample collection during follow-up.

Who Is Running the Clinical Trial?

Fred Hutchinson Cancer Center

Lead Sponsor

Trials

583

Recruited

1,341,000+

National Cancer Institute (NCI)

Collaborator

Trials

14,080

Recruited

41,180,000+

National Cancer Institute Center to Reduce Cancer Health Disparities

Collaborator

Trials

1

Recruited

120+

New Mexico State University

Collaborator

Trials

10

Recruited

2,100+

References

1. Canada pubmed.ncbi.nlm.nih.gov

An Avatar-Led Digital Smoking Cessation Program for Sexual and Gender Minority Young Adults: Intervention Development and Results of a Single-Arm Pilot Trial. [2021]

2. England pubmed.ncbi.nlm.nih.gov

A qualitative study of tobacco interventions for LGBTQ+ youth and young adults: overarching themes and key learnings. [2018]

3. England pubmed.ncbi.nlm.nih.gov

Evaluation of a Randomized Clinical Trial Comparing the Effectiveness of a Culturally Targeted and Nontargeted Smoking Cessation Intervention for Lesbian, Gay, Bisexual, and Transgender Smokers. [2023]

4. England pubmed.ncbi.nlm.nih.gov

Smoking cessation treatment preferences, intentions, and behaviors among a large sample of Colorado gay, lesbian, bisexual, and transgendered smokers. [2015]

5. United States pubmed.ncbi.nlm.nih.gov

Results from a community-based smoking cessation treatment program for LGBT smokers. [2022]

6. England pubmed.ncbi.nlm.nih.gov

LGBTQ Utilization of a Statewide Tobacco Quitline: Engagement and Quitting Behavior, 2010-2022. [2023]

7. England pubmed.ncbi.nlm.nih.gov

Sexual and gender minority young adults' smoking characteristics: Assessing differences by sexual orientation and gender identity. [2020]