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Math & Cognitive Skill Interventions for Dyscalculia

N/A
Recruiting
Research Sponsored by Stanford University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Normal or corrected-to-normal vision and no hearing impairments
Be younger than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and post-intervention (after 6 weeks)
Awards & highlights

Study Summary

This trial looks at ways to help children with weak math skills, including those with MLD, to improve their numerical skills. #math #learningdisabilities

Who is the study for?
This trial is for elementary school children aged 6-12 with an IQ over 70. It's aimed at those struggling with math, scoring below the 25-35th percentile in certain tests, and typically developing kids who score above that range. Participants must have normal vision and hearing, be right-handed for MRI scans, and not have psychiatric disorders or head injuries.Check my eligibility
What is being tested?
The study is testing educational interventions to improve mathematical skills in children with learning disabilities compared to typical development. It examines how these interventions affect brain function and decision-making related to numbers.See study design
What are the potential side effects?
Since this trial involves educational interventions rather than medical treatments, traditional side effects are not applicable. However, participants may experience fatigue or stress from testing situations.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
My vision is normal or corrected to normal, and I don't have hearing problems.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and post-intervention (after 6 weeks)
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and post-intervention (after 6 weeks) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change from baseline in brain activation during non-symbolic number comparison task performance
Change from baseline in brain activation during symbolic number comparison task performance
Change from baseline in functional connectivity during symbolic addition task performance
+8 more
Secondary outcome measures
Change from baseline in functional connectivity during non-symbolic number comparison task performance
Change from baseline in functional connectivity during symbolic number comparison task performance
Change from baseline in symbolic addition task performance (accuracy)
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Integrative Symbolic Non-Symbolic (iSNS) TrainingExperimental Treatment1 Intervention
Integrative symbolic non-symbolic (iSNS) training: Over a period of 6 weeks, participants will complete activities that progressively strengthen the mapping of symbolic numerical representations to non-symbolic numerical quantities and enhance fluency in symbolic numerical skills.
Group II: Active Comparator: Active Control Intervention (Working Memory Training)Active Control1 Intervention
Active control intervention: Over a period of 6 weeks, participants will complete activities that enhance short-term storage and maintenance of visuospatial or verbal information.

Find a Location

Who is running the clinical trial?

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NIH
1,965 Previous Clinical Trials
2,672,617 Total Patients Enrolled
Stanford UniversityLead Sponsor
2,395 Previous Clinical Trials
17,341,175 Total Patients Enrolled

Media Library

Interventions in Mathematics and Cognitive Skills (Other) Clinical Trial Eligibility Overview. Trial Name: NCT05201534 — N/A
Cognitive Impairment Research Study Groups: Integrative Symbolic Non-Symbolic (iSNS) Training, Active Comparator: Active Control Intervention (Working Memory Training)
Cognitive Impairment Clinical Trial 2023: Interventions in Mathematics and Cognitive Skills Highlights & Side Effects. Trial Name: NCT05201534 — N/A
Interventions in Mathematics and Cognitive Skills (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05201534 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are participants over the age of 65 welcome to join this research initiative?

"This trial is open to all children aged 6-12."

Answered by AI

What criteria must potential participants meet in order to join this research?

"This academic research project requires participants to be aged between 6 and 12, possessing a basic grasp of mathematics. A total of 180 students are required for the study."

Answered by AI

Are there any openings available in this research initiative?

"According to the current information found on clinicaltrials.gov, this medical study is still in need of patient recruitment. It was initially posted on May 5th 2023 and was most recently updated two weeks later on May 15th 2023."

Answered by AI

How many individuals are eligible to participate in this clinical trial?

"Affirmative. According to the medical records hosted on clinicaltrials.gov, this study is still recruiting patients since its initial post date of May 5th 2023 and subsequent edits thereafter. 180 individuals are needed for this trial from a single site."

Answered by AI

What are the paramount goals of this experiment?

"This trial will assess cognitive changes over a baseline and post-intervention (after 8 weeks) period, chiefly by measuring drift rate during symbolic number comparison. Other metrics which will be observed include functional connectivity between ventrotemporal occipital cortex (VTOC), posterior parietal cortex (PPC), prefrontal cortex (PFC), medial temporal lobe (MTL), and basal ganglia regions during non-symbolic comparisons via gPPI beta values obtained from individual subject contrast maps for Near vs. Far contrasts; accuracy (% trials correct) on the symbolic addition task; as well as reaction time in milliseconds of children completing the same"

Answered by AI
~120 spots leftby Jun 2026