Auricular Vagus Nerve Stimulation for Stroke
What You Need to Know Before You Apply
What is the purpose of this trial?
This study will evaluate whether non-invasive auricular vagal nerve stimulation lowers inflammatory markers, and improves outcomes following intracerebral hemorrhage.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. Please consult with the trial coordinators for more details.
Is auricular vagus nerve stimulation safe for humans?
How is auricular vagus nerve stimulation different from other stroke treatments?
Auricular vagus nerve stimulation (aVNS) is unique because it is a non-invasive treatment that stimulates the vagus nerve through the skin of the outer ear, unlike traditional methods that require surgery. This approach is novel for stroke recovery as it can improve motor and sensory functions without the need for surgical intervention.46789
What data supports the effectiveness of the treatment Auricular Vagus Nerve Stimulation for stroke?
Who Is on the Research Team?
Eric Leuthardt, MD MBA
Principal Investigator
Washington University School of Medicine
Are You a Good Fit for This Trial?
This trial is for adults with a spontaneous stroke in the upper part of their brain. They must be treated at Barnes Jewish Hospital within 48 hours of the stroke and not have cancer treatment or planned surgery, except ventriculostomy. It's not for those under 18, with very large or small strokes, traumatic causes, extremely low responsiveness (GCS of 3), unreactive pupils, or very slow heart rates.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either auricular vagal nerve stimulation or sham stimulation twice daily
Follow-up
Participants are monitored for safety and effectiveness after treatment, with functional scores assessed at discharge and follow-up visits
What Are the Treatments Tested in This Trial?
Interventions
- Auricular Vagus Nerve Stimulation
- Sham Auricular Vagus nerve Stimulation
Find a Clinic Near You
Who Is Running the Clinical Trial?
Washington University School of Medicine
Lead Sponsor