Music and Theta Auditory Beat Stimulation for Pink Noise (Control)

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Toronto Metropolitan University, Toronto, Canada
Pink Noise (Control)+3 More
Music and Theta Auditory Beat Stimulation - Behavioral
Eligibility
18 - 65
All Sexes
What conditions do you have?
Select

Study Summary

Anxiety is a growing problem and has been steadily increasing, particularly in the adolescent and young adult populations in the past 24 years. Music and auditory beat stimulation (ABS) in the theta frequency range (4-7 Hz) are sound-based anxiety treatments that have been investigated in prior studies with subjective measures of anxiety. Here, the anxiety-reducing potential of calm music combined with theta ABS will be examined in a large sample of participants with objective psychophysiological measures (heart rate variability and EEG), stress hormone measures (salivary cortisol) along with subjective measures (STICSA state). Participants with moderate trait anxiety (n = 100) will be randomly assigned to a single 24-minute session of sound-based treatment: combined (music & ABS), or pink noise (control). Pre- and post-intervention heart rate variability and EEG band power (alpha, beta, delta, and theta bands), along with somatic and cognitive state anxiety measures (STICSA State) will be collected along with trait anxiety (STICSA Trait), and musical preferences (Short Test of Music Preferences). Our hypothesis is that the music & ABS condition will have significantly higher EEG theta band activity and heart rate variability compared to the pink noise control condition. The investigators also expect to see significantly reduces higher state anxiety reduction in the music & ABS condition compared to the pink noise control condition. Participants with moderate trait anxiety (n = 100) will be randomly assigned to a single 24-minute session of sound-based treatment: combined (music & ABS), or pink noise (control). Pre- and post-intervention heart rate variability and EEG band power (alpha, beta, delta, and theta bands), along with somatic and cognitive state anxiety measures (STICSA State) will be collected along with trait anxiety (STICSA Trait), and musical preferences (Short Test of Music Preferences). The investigators predict that the music & ABS condition will have significantly increased power in the theta and alpha bands, higher heart rate variability, higher state anxiety reduction, and lower salivary cortisol levels compared to the pink noise control condition.

Eligible Conditions

  • Pink Noise (Control)
  • State Anxiety
  • Music and Theta Auditory Beat Stimulation

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Pink Noise (Control)

Study Objectives

4 Primary · 1 Secondary · Reporting Duration: 24 minutes

24 minutes
Anxiety: EEG band power (alpha, beta, delta and theta bands)
Anxiety: Heart rate variability (HRV)
Anxiety: State Trait Inventory for Cognitive and Somatic Anxiety (STICSA)
Anxiety: Stress hormone levels: Salivary cortisol
Mood: Positive and Negative Affect Scale (PANAS)

Trial Safety

Safety Progress

1 of 3

Other trials for Pink Noise (Control)

Trial Design

2 Treatment Groups

Music and Theta Auditory Beat Stimulation
1 of 2
Pink Noise (control)
1 of 2
Experimental Treatment
Non-Treatment Group

100 Total Participants · 2 Treatment Groups

Primary Treatment: Music and Theta Auditory Beat Stimulation · Has Placebo Group · N/A

Music and Theta Auditory Beat Stimulation
Behavioral
Experimental Group · 1 Intervention: Music and Theta Auditory Beat Stimulation · Intervention Types: Behavioral
Pink Noise (control)
Behavioral
ShamComparator Group · 1 Intervention: Pink Noise (control) · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 24 minutes

Trial Background

Prof. Frank Russo, Professor
Principal Investigator
Ryerson University
Closest Location: Toronto Metropolitan University · Toronto, Canada
Photo of Toronto  1Photo of Toronto  2Photo of Toronto  3
N/AFirst Recorded Clinical Trial
1 TrialsResearching Pink Noise (Control)
0 CompletedClinical Trials

Eligibility Criteria

Age 18 - 65 · All Participants · 4 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have no known cardiac issues.
You have normal hearing.
You have no known epilepsy/seizures.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

References