Sleep Management for Childhood Obesity
Trial Summary
Do I have to stop taking my current medications?
Yes, if you are taking medication known to affect sleep or appetite, you will need to stop taking it to participate in the trial.
What data supports the idea that Sleep Management for Childhood Obesity is an effective treatment?
The available research shows that extending sleep duration can help with weight loss in adolescents with obesity. One study found that when sleep extension was combined with a diet, it increased weight loss and improved inflammation, which is a sign of better health. Another study showed that longer sleep each week was linked to a greater reduction in body mass index (BMI) over three months in obese adolescents. These findings suggest that sleep management can be an effective part of treating childhood obesity.12345
What safety data exists for sleep management in childhood obesity treatment?
The research does not directly address safety data for sleep management treatments like sleep extension or restriction in childhood obesity. However, studies suggest that sleep interventions can positively impact weight management and reduce obesity risk in children, indicating potential benefits without highlighting specific safety concerns.13678
Is sleep extension a promising treatment for managing childhood obesity?
Yes, sleep extension is a promising treatment for managing childhood obesity. Research shows that getting more sleep can help with weight loss and reduce the risk of becoming overweight. Extending sleep duration can improve the effects of a healthy diet and may help prevent obesity in children.14679
What is the purpose of this trial?
Overweight/obesity and inadequate sleep are prevalent, and frequently co-occurring, health risks among children, both of which are associated with serious medical and psychosocial health complications including risk for cardiovascular disease. Although the investigator's data suggest that disrupted or shortened sleep may be causally associated with increased energy intake and weight gain in children, and with self-regulation and neural response to food cues in adults, understanding of mechanisms involved in the sleep/eating association is incomplete, thereby impeding development of targeted, optimally timed intervention strategies. The proposed mechanistic clinical trial aims to assess the effects of an experimental sleep manipulation on eating-related self-regulation and its neural substrates, and on real-world eating behavior, among children with overweight/obesity, which will help guide research efforts towards the refinement of prevention and intervention strategies targeting sleep and its eating-related correlates to curb weight gain throughout development.
Research Team
Andrea B Goldschmidt, Ph.D.
Principal Investigator
University of Pittsburgh
Eligibility Criteria
This trial is for children who are overweight or obese and willing to have an MRI scan. It's not suitable for those with conditions affecting brain function, like a recent concussion, more than 10 hours of sleep per night, past eating disorders, sleep or psychiatric conditions, or if they're on medications that affect sleep or appetite.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Assessment of typical sleep and eating patterns using actigraphy and self-reports
Sleep Manipulation
Participants undergo sleep restriction or extension in a randomized crossover design
Wash-out Period
A 7-day wash-out period between sleep manipulation phases
Follow-up
Participants are monitored for changes in eating behavior and self-regulatory control
Treatment Details
Interventions
- Sleep extension
- Sleep restriction
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Pittsburgh
Lead Sponsor
The Miriam Hospital
Lead Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Collaborator