Corneal Collagen Cross-Linking Techniques for Keratoconus
What You Need to Know Before You Apply
What is the purpose of this trial?
This is a prospective, randomized, single investigative site study to compare the safety and effectiveness of Epi-OFF CXL treatment (performed using Ricrolin+ and VEGA UV-A system) compared to Epi-ON CXL (performed using Ricrolin+ and VEGA UV-A system) in eyes with keratoconus and other corneal ectatic disorders.Subjects will be randomized to receive the CXL treatment with either the Epi-On or Epi-Off technique.
Are You a Good Fit for This Trial?
This trial is for individuals at least 12 years old with keratoconus or other corneal ectatic disorders. Participants must provide consent, have specific topography map changes, and be willing to use birth control if applicable. Those with prior CXL treatment, corneal transplants, certain ocular conditions, allergies to study materials, or inadequate corneal thickness are excluded.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either Epi-ON or Epi-OFF corneal collagen cross-linking treatment
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Epi-OFF
- Epi-ON
- Ricrolin+
- VEGA UV-A system
Find a Clinic Near You
Who Is Running the Clinical Trial?
Center for Sight, Sacramento, CA
Lead Sponsor