Red Light Therapy for Peripheral Artery Disease
Trial Summary
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of Red Light Therapy for Peripheral Artery Disease?
Is red light therapy safe for humans?
How does Red Light Therapy differ from other treatments for Peripheral Artery Disease?
Red Light Therapy is unique because it uses non-invasive light at a specific wavelength (670 nm) to potentially improve blood flow, unlike traditional laser treatments that physically remove blockages in arteries. This approach may offer a gentler alternative with fewer risks of damaging the arterial walls.14101112
What is the purpose of this trial?
This trial involves shining a special red light on the calf muscle of patients with poor leg blood flow due to peripheral artery disease. The goal is to see if this light can improve blood flow by helping the blood vessels work better, possibly through increasing nitric oxide levels.
Research Team
Nicole L Lohr, MD,PHD
Principal Investigator
Medical College of Wisconsin
Eligibility Criteria
This trial is for adults aged 18-85 with peripheral artery disease, indicated by an ankle brachial index outside the normal range. It's open to all ethnicities. Excluded are those under 18 or over 85, pregnant women, individuals sensitive to perflutren contrast agents, those with uncontrolled medical conditions like high blood pressure or sickle cell disease, and people who can't understand the consent process.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo a single 5-minute exposure to 670 nm light, with blood flow measured by ultrasound and blood samples collected for nitric oxide metabolites
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Red Light Treatment
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Alabama at Birmingham
Lead Sponsor
Medical College of Wisconsin
Lead Sponsor