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Light Therapy

Red Light Therapy for Peripheral Artery Disease

N/A
Recruiting
Led By Nicole L Lohr, MD,PHD
Research Sponsored by Medical College of Wisconsin
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Diagnosis of peripheral artery disease is defined as an Ankle Brachial index of <0.9 or >1.1 at rest or during treadmill exercise
Men and women of all ethnicities are eligible for participation
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and 1 min after discontinuation of light
Awards & highlights

Study Summary

This trial is testing whether a single 5 minute exposure of 670 nm light can improve blood flow in people with peripheral artery disease.

Who is the study for?
This trial is for adults aged 18-85 with peripheral artery disease, indicated by an ankle brachial index outside the normal range. It's open to all ethnicities. Excluded are those under 18 or over 85, pregnant women, individuals sensitive to perflutren contrast agents, those with uncontrolled medical conditions like high blood pressure or sickle cell disease, and people who can't understand the consent process.Check my eligibility
What is being tested?
The study tests a single five-minute exposure of red light therapy on the lower leg muscle in patients with peripheral artery disease. The aim is to see if this treatment improves blood flow as measured by ultrasound after injecting a special contrast agent. Blood samples will also be taken to check for changes in nitric oxide levels.See study design
What are the potential side effects?
Potential side effects may include reactions at the site of red light exposure such as skin irritation or discomfort. There might also be risks associated with the ultrasound contrast agent used during imaging, including allergic reactions or side effects related to nitric oxide metabolite measurement.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I have been diagnosed with peripheral artery disease.
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I am eligible regardless of my gender or ethnicity.
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I am between 18 and 85 years old and have been diagnosed with peripheral artery disease.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 5 min of light, and up to 1 min after discontinuation of light
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 5 min of light, and up to 1 min after discontinuation of light for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Changes in blood flow
Secondary outcome measures
Changes in nitric oxide metabolites

Trial Design

1Treatment groups
Experimental Treatment
Group I: Red Light treatmentExperimental Treatment2 Interventions
This is a single arm design. All subjects will be enrolled to have peripheral blood flow measured before, during, and after red light exposure.

Find a Location

Who is running the clinical trial?

Medical College of WisconsinLead Sponsor
608 Previous Clinical Trials
1,162,471 Total Patients Enrolled
4 Trials studying Peripheral Arterial Disease
130 Patients Enrolled for Peripheral Arterial Disease
Nicole L Lohr, MD,PHDPrincipal InvestigatorMedical College of Wisconsin

Media Library

Red Light Treatment (Light Therapy) Clinical Trial Eligibility Overview. Trial Name: NCT03203239 — N/A
Peripheral Arterial Disease Research Study Groups: Red Light treatment
Peripheral Arterial Disease Clinical Trial 2023: Red Light Treatment Highlights & Side Effects. Trial Name: NCT03203239 — N/A
Red Light Treatment (Light Therapy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03203239 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are individuals still being accepted to participate in this clinical trial?

"Per the listings on clinicaltrials.gov, this research project is still enrolling participants and has been since January 17th 2018. The entry was last modified on May 9th 2022."

Answered by AI

Is this research open to elderly participants?

"The parameters for inclusion in this medical test state that applicants must be within the age range of 18 to 85. Separately, 13 trials are available specifically to minors while 247 clinical studies are tailored to those aged 65 and above."

Answered by AI

Under what criteria are participants eligible to join this research?

"This research is actively seeking out 40 individuals, aged between 18 and 85, who are currently experiencing vasodilation. To be included in the study, patients must have been diagnosed with peripheral artery disease; recruitment will not discriminate on gender or ethnicity."

Answered by AI

What is the total number of participants enrolled in this trial?

"Affirmative. Clinicaltrials.gov provides information that this medical trial, which was initially published on the 17th of January 2018, is presently recruiting volunteers. The research requires 40 patients to be drawn from a single center."

Answered by AI

What is the predominant application of Red Light (670 nm energy)?

"Through the use of Red Light (670 nm energy), medical professionals can combat echocardiography, cardiovascular diseases, and diagnostic imaging."

Answered by AI

Are there any other investigations which have utilized Red Light (670 nm energy)?

"At present, 19 investigations of Red Light (670 nm energy) are underway with one in its third phase. Most examinations take place within Philadelphia, Pennsylvania yet there are 26 other places where the research is being conducted."

Answered by AI
~4 spots leftby Dec 2024