Cognitive Processing Therapy vs. Relaxation Training for PTSD
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests two treatments to reduce PTSD (posttraumatic stress disorder) symptoms. One group will undergo Cognitive Processing Therapy (CPT), which includes 10 virtual therapy sessions over five days. The other group will participate in relaxation training, with five virtual sessions in five days. The trial aims to determine which treatment is more effective and how they function. Individuals diagnosed with PTSD, who have experienced past trauma, are interested in these treatments, and reside in Illinois may be suitable candidates for this trial. As an unphased trial, this study provides a unique opportunity to explore new therapeutic options for PTSD.
Do I have to stop taking my current medications for the trial?
The trial does not specify if you need to stop taking your current medications, but you must have been on a stable dose of any psychotropic medication for at least one month before starting the trial.
What prior data suggests that these treatments are safe for PTSD?
Research has shown that Cognitive Processing Therapy (CPT) is generally easy for people to handle. Studies found that only 6.9% of participants stopped the treatment, suggesting that most can complete the therapy without major issues.
CPT has successfully helped people with PTSD and related issues like depression and suicidal thoughts. It has lasting positive effects on PTSD symptoms and overall mental health, indicating that the therapy is safe and effective for many.
Relaxation Training (RT) is another common method that helps manage stress and anxiety. It is considered safe and is widely used for various mental health conditions. Reports of negative effects are rare, making it a low-risk option for most participants.
Overall, both treatments in this clinical trial have a history of being safe and well-tolerated by participants.12345Why are researchers excited about this trial?
Researchers are excited about these treatments for PTSD because they offer unique approaches compared to traditional options like medication or talk therapy. Cognitive Processing Therapy (CPT) stands out as it focuses on changing painful negative beliefs related to the trauma, potentially leading to deeper emotional healing. Relaxation Training (RT), on the other hand, emphasizes reducing physical tension and stress, which can be a safe and simple way to alleviate PTSD symptoms. Both approaches offer non-medication alternatives that could provide new avenues for people who haven't found relief with standard treatments.
What evidence suggests that this trial's treatments could be effective for PTSD?
This trial will compare Cognitive Processing Therapy (CPT) with Relaxation Training (RT) for treating PTSD. Research has shown that CPT, which participants in this trial may receive, effectively treats PTSD. Several studies have found that people who undergo CPT experience a significant reduction in PTSD symptoms. For example, one study noted a decrease of about 14 points on a PTSD symptom scale, marking a substantial improvement. Another study found that the benefits of CPT lasted for months after the treatment ended. Overall, CPT has proven to help many people with PTSD, providing lasting relief from symptoms.
In contrast, Relaxation Training (RT), another treatment option in this trial, is often used to help manage stress but lacks the same strong evidence for reducing PTSD symptoms specifically. While relaxation techniques can be calming and may help with anxiety, CPT has a more established record for directly addressing PTSD.12367Are You a Good Fit for This Trial?
This trial is for English-speaking adults with PTSD who are interested in intensive therapy. Participants must have experienced a traumatic event, be stable on any psychotropic meds for at least a month, and commit to daily sessions over one week. Exclusions include recent trauma, unstable medical conditions, current legal actions related to the trauma, unmanaged psychosis or mania, recent substance abuse treatment needs, and sensory impairments.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo 1-week virtual massed Cognitive Processing Therapy (CPT) or 5-day virtual relaxation training (RT) to reduce PTSD symptoms
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Cognitive Processing Therapy
- Relaxation Training
Cognitive Processing Therapy is already approved in United States, European Union for the following indications:
- Posttraumatic Stress Disorder (PTSD)
- Posttraumatic Stress Disorder (PTSD)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Rush University Medical Center
Lead Sponsor