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Fruit and Vegetable Juice Concentrate

Juice Plus+ for Alzheimer's Disease

Waitlist Available
Led By Raheem Paxton, PhD
Research Sponsored by University of Alabama, Tuscaloosa
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Screening 3 weeks
Treatment Varies
Follow Up baseline, year, 1, and year 2.
Awards & highlights


This trial will study whether fruit and vegetable juice concentrates can improve cognitive abilities and memory.

Eligible Conditions
  • Early-Onset Alzheimer's Disease
  • Cognitive Impairment
  • Mild Cognitive Impairment


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, year, 1, and year 2.
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, year, 1, and year 2. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in C-reactive protein
Change in Interleukin -5
Change in Interleukin 6
+1 more
Secondary outcome measures
Auditory Very Learning Test
Stroop Test
Trial Making task

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Juice Plus+Experimental Treatment1 Intervention
Participants will consume 6 capsules daily consisting of a combination of Juice Plus+ Garden Blend, Juice Plus+ Orchard Blend and Juice Plus+ Berry Blend. Participants will consume supplements for 24-months.
Group II: PlaceboPlacebo Group1 Intervention
Participants will consume 6 capsules daily consisting of microcrystalline cellulose, rice starch, vegetarian capsule (cellulose), and magnesium stearate. Participants in this condition will receive 1-year of supplements after the study is completed.
First Studied
Drug Approval Stage
How many patients have taken this drug
Juice Plus+

Find a Location

Who is running the clinical trial?

University of Alabama, TuscaloosaLead Sponsor
45 Previous Clinical Trials
19,477 Total Patients Enrolled
University of North Texas Health Science CenterOTHER
40 Previous Clinical Trials
20,656 Total Patients Enrolled
Raheem Paxton, PhDPrincipal InvestigatorUniversity of Alabama at Birmingham
2 Previous Clinical Trials
458 Total Patients Enrolled
~28 spots leftby Jul 2025