Cranberry Juice Product for Attention

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Atlantia Clinical Trials Ltd, Chicago, IL
Attention+1 More
Cranberry Juice Product - DietarySupplement
Eligibility
18 - 65
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether cranberry juice, lemon balm, or tart cherry powder can improve cognitive function and mood in healthy adults.

See full description

Eligible Conditions

  • Attention
  • Mood

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Cranberry Juice Product will improve 1 primary outcome, 6 secondary outcomes, and 6 other outcomes in patients with Attention. Measurement will happen over the course of 7 days.

7 days
To evaluate in healthy adults the effect of 7-day consumption of cranberry beverages compared to placebo on attention.
To evaluate in healthy adults the effect of 7-day consumption of cranberry beverages compared to placebo on measures of alertness.
To evaluate in healthy adults the effect of 7-day consumption of cranberry beverages compared to placebo on measures of cognition (accuracy of performance).
To evaluate in healthy adults the effect of 7-day consumption of cranberry beverages compared to placebo on measures of cognition (speed of performance).
To evaluate in healthy adults the effect of 7-day consumption of cranberry beverages compared to placebo on measures of focus.
To evaluate in healthy adults the effect of 7-day consumption of cranberry beverages compared to placebo on mood.
To evaluate in healthy adults the effect of 7-day consumption of cranberry beverages compared to placebo on stress.
To evaluate in healthy adults the safety and tolerability of 7-day consumption of cranberry beverages compared to placebo (Blood Pressure).
To evaluate in healthy adults the safety and tolerability of 7-day consumption of cranberry beverages compared to placebo (Body Temperature).
To evaluate in healthy adults the safety and tolerability of 7-day consumption of cranberry beverages compared to placebo (Heart Rate).
To evaluate in healthy adults the safety and tolerability of 7-day consumption of cranberry beverages compared to placebo (Incidence of Adverse Events).
To evaluate in healthy adults the safety and tolerability of 7-day consumption of cranberry beverages compared to placebo (Incidence of Serious Adverse Events).
To evaluate in healthy adults the safety and tolerability of 7-day consumption of cranberry beverages compared to placebo (Proportion of Adverse Events).

Trial Safety

Trial Design

6 Treatment Groups

Second Product Order: order not stated to protect study blinding
1 of 6
Third Product Order: order not stated to protect study blinding
1 of 6
Fifth Product Order: order not stated to protect study blinding
1 of 6
First Product Order: order not stated to protect study blinding
1 of 6
Fourth Product Order: order not stated to protect study blinding
1 of 6
Sixth Product Order: order not stated to protect study blinding
1 of 6
Experimental Treatment

This trial requires 25 total participants across 6 different treatment groups

This trial involves 6 different treatments. Cranberry Juice Product is the primary treatment being studied. Participants will be divided into 6 treatment groups. There is no placebo group. The treatments being tested are in Phase < 1 and are in the first stage of evaluation with people.

Second Product Order: order not stated to protect study blinding
DietarySupplement
Participants will receive each of the 6 study products sequentially in a cross-over design, consuming one study product for 7 days, followed by a 7 day wash-out period before beginning the next product in the sequence
Third Product Order: order not stated to protect study blinding
DietarySupplement
Participants will receive each of the 6 study products sequentially in a cross-over design, consuming one study product for 7 days, followed by a 7 day wash-out period before beginning the next product in the sequence
Fifth Product Order: order not stated to protect study blinding
DietarySupplement
Participants will receive each of the 6 study products sequentially in a cross-over design, consuming one study product for 7 days, followed by a 7 day wash-out period before beginning the next product in the sequence
First Product Order: order not stated to protect study blinding
DietarySupplement
Participants will receive each of the 6 study products sequentially in a cross-over design, consuming one study product for 7 days, followed by a 7 day wash-out period before beginning the next product in the sequence.
Fourth Product Order: order not stated to protect study blinding
DietarySupplement
Participants will receive each of the 6 study products sequentially in a cross-over design, consuming one study product for 7 days, followed by a 7 day wash-out period before beginning the next product in the sequence
Sixth Product Order: order not stated to protect study blinding
DietarySupplement
Participants will receive each of the 6 study products sequentially in a cross-over design, consuming one study product for 7 days, followed by a 7 day wash-out period before beginning the next product in the sequence

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 7 days
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 7 days for reporting.

Closest Location

Atlantia Clinical Trials Ltd - Chicago, IL

Eligibility Criteria

This trial is for patients born any sex between 18 and 65 years old. There are 10 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
You must be at least 18 years old, but no more than 45 years old. show original
The subject is in good health, as determined by the investigator. show original
Has a BMI of 20 to 35 kg/m2. show original
The person has a score on the Beck Depression Inventory II of 20 or less at screening. show original
The subject agreed to stop consuming wine, dark red/blue colored fruits, and polyphenol-rich fruits (e.g., pomegranate, blueberries, grapes), lemon balm, tart cherry powder, and L-Theanine for two weeks before the study and during the study. show original
Is willing to provide a saliva sample. show original
Please continue your current level of physical activity and dietary habits throughout the study. show original
I am able to give written informed consent and am willing/able to comply with study procedures. show original
Has not had a significant change in weight over the past 3 months. show original
The subject was willing and able to avoid consumption of any cranberry juice, whole cranberries, and dried cranberries for the two weeks leading up to the study (from the Screening visit V1 to baseline V2) and during the study, excluding the study beverage. show original

Patient Q&A Section

What are the signs of mood?

"Symptoms that characterize mood are often more subjective, and signs often manifest as mood swings which can become chronic or recurrent. Symptoms consistent with mood may include: hopelessness, increased irritability, inability to concentrate, social isolation, or feelings of anger.\n" - Anonymous Online Contributor

Unverified Answer

What causes mood?

"mood is related to our thoughts about life events, our self-image, and our opinions about other people. mood is not only about what's happening, but also about our thoughts and beliefs about what's happening. As a result, mood-related issues are extremely salient in the treatment of patients with psychiatric conditions in general, and in particular individuals with mood disorders." - Anonymous Online Contributor

Unverified Answer

How many people get mood a year in the United States?

"The American Psychiatric Association expects 12.4 million new diagnoses will be made in 2013 on mood disorders and 4.4 million on anxiety and related conditions. It is projected that 0.8 million Americans will suffer from severe symptomatology. These data suggest that around 10 million Americans can expect a new diagnosis of a mood or anxiety disorder or severe mood disturbance during this period." - Anonymous Online Contributor

Unverified Answer

Can mood be cured?

"As mood is a predisposing factor in some diseases, our findings show that it could be a useful marker and a risk factor for disease progression. This underscores the need for more definitive treatments aimed at correcting mood disturbances by pharmacological or psychosocial means in patients suffering from cancer." - Anonymous Online Contributor

Unverified Answer

What is mood?

"Mood refers to the emotions experienced individually in response to the environment, and can be either positive or negative, or combinations of these two. Mood is an internal and multi-dimensional construct and encompasses aspects of all emotions and the self-image. Depression is a mood disorder characterized by an overall reduction in mood functioning and can be either a mood state or mood trait." - Anonymous Online Contributor

Unverified Answer

What are common treatments for mood?

"Medications play an important role in treating mood disorders, but it is important to first rule out depression and hypomania as possibilities. The presence of depression is strongly associated with hypomania. Other treatments of mood disorders are psychosocial, such as psychotherapeutic interventions and cognitive behavioral therapy. It is important to recognize the possibility of comorbid mood disorders such as seasonal affective disorder (SAD) and bipolar disorder, particularly when untreated. Treatment is aimed at treating mood symptoms at the level of the individual, rather than treating the underlying cause of the problems.\n\nMental health issues are highly prevalent among members of the workforce." - Anonymous Online Contributor

Unverified Answer

What is the average age someone gets mood?

"This is the first study to reveal an average age in American society when someone becomes mildly depressed. It was between 13 and 14 years old. Previous studies in the UK and Europe revealed higher figures. This is also the first study to provide an average age of depressive symptoms onset at 16.3 years. In a recent study, findings point to the need for depressive and bipolar disorder prevention and intervention programmes during adolescents." - Anonymous Online Contributor

Unverified Answer

Does cranberry juice product improve quality of life for those with mood?

"The use of a cranberry juice product did not cause increased overall quality of life as measured by health-related quality-of-life tools among those with and without mood symptoms. There was no effect on the three mood-related health-related quality-of-life tools, but there was an effect on four general quality-of-life tools." - Anonymous Online Contributor

Unverified Answer

Does mood run in families?

"Results from a recent paper indicate that common variants in the serotonin (5-HT) and adrenergic (ADR) systems predispose to mood disorder through their effects on mood, motivation, and reward." - Anonymous Online Contributor

Unverified Answer

What is the primary cause of mood?

"Mood is one of many factors affecting work performance and is influenced by the environment. For example, work-related factors, such as job demands and job satisfaction, can affect mood. [Power] Depression is most often caused by recurrent episodic events, including loss of [a significant other], unemployment, work stress, or death of a loved one[s]." - Anonymous Online Contributor

Unverified Answer

What is the latest research for mood?

"Treating mood disorders is highly effective and inexpensive, and this approach is the most promising in alleviating depressive symptoms. Nevertheless, the search for a molecular biomarker with therapeutic potential as a treatment of mood disorders has yet to be feasible. The most promising avenue is gene-targeting therapies." - Anonymous Online Contributor

Unverified Answer

What are the latest developments in cranberry juice product for therapeutic use?

"The new cranberry juice product is well tolerated and possesses pharmacologic properties which contribute to its potential therapeutic benefits. [Power(http://www.withpower.com/clinical-trials/cranberry-juice-clinical-trials) make it easy to find cranberry juice clinical trials tailored to your condition, treatment, or location. Visit the [Withpower(http://withpower.com/cranberry-juice-clinical-trials)] website to learn more about matching a patient with a clinical trial near you." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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