Aronia Berry Extract Applesauce for Metabolism

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of Wisconsin, Madison, WI
Metabolism+2 More
Aronia Berry Extract Applesauce - DietarySupplement
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

The objective of this study is to conduct a randomized cross-over dietary intervention among healthy adults to compare the bioavailability and the fecal polyphenol metabolites of intervention foods made with whole aronia berry powder, aronia berry extract, phospholipid-polyphenol (PLP), and a low-polyphenol control. 10 participants will be enrolled and can expect to be on study for up to 28 days.

Eligible Conditions

  • Gut Health
  • Metabolism
  • Polyphenols

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

5 Primary · 0 Secondary · Reporting Duration: sampled on day 6, 13, 20, and 27 (participant randomized to different interventions each visit)

Day 6
Fecal Anthocyanin Concentration
Fecal Polyphenol Catabolite Concentration
Urinary Anthocyanin Concentration
Urinary Polyphenol Catabolite Concentration
Urine Creatinine Content

Trial Safety

Safety Progress

1 of 3

Trial Design

4 Treatment Groups

B: Aronia Berry Extract
1 of 4
C: Phospholipid-Polyphenol
1 of 4
A: Whole Aronia Berry Powder
1 of 4
D: Low-Polyphenol Control
1 of 4
Experimental Treatment

10 Total Participants · 4 Treatment Groups

Primary Treatment: Aronia Berry Extract Applesauce · No Placebo Group · N/A

B: Aronia Berry Extract
DietarySupplement
Experimental Group · 1 Intervention: Aronia Berry Extract Applesauce · Intervention Types: DietarySupplement
C: Phospholipid-Polyphenol
DietarySupplement
Experimental Group · 1 Intervention: Phospholipid-Polyphenol Applesauce · Intervention Types: DietarySupplement
A: Whole Aronia Berry Powder
DietarySupplement
Experimental Group · 1 Intervention: Whole Aronia Berry Powder Applesauce · Intervention Types: DietarySupplement
D: Low-Polyphenol Control
Other
Experimental Group · 1 Intervention: Low-Polyphenol Control Applesauce · Intervention Types: Other

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: sampled on day 6, 13, 20, and 27 (participant randomized to different interventions each visit)
Closest Location: University of Wisconsin · Madison, WI
Photo of wi university of wisconsin 1Photo of madison 2Photo of madison 3
2003First Recorded Clinical Trial
1 TrialsResearching Metabolism
383 CompletedClinical Trials

Who is running the clinical trial?

University of Wisconsin, MadisonLead Sponsor
1,052 Previous Clinical Trials
2,559,901 Total Patients Enrolled
Bradley Bolling, PhDPrincipal InvestigatorUniversity of Wisconsin, Madison

Eligibility Criteria

Age 18+ · All Participants · 3 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You are willing to provide 24-hour urine and fecal samples during the sampling periods.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.