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Study Summary
This trial is testing a new drug for safety in people with mild memory problems or Alzheimer's. The drug is given at different levels to different groups to find a safe dose. Healthy older adults may also participate.
Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Logistics
Participation is compensated
You will be compensated for participating in this trial.
Who is running the clinical trial?
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- I am on ongoing medication for an active autoimmune disease.I do not have any unstable or poorly controlled health conditions.I have been treated with aducanumab or similar therapy in the past 6 months.I have had cancer before.I haven't had biological therapy or immunoglobulin in the time frame required.I haven't had non-live vaccines around my treatment, except for COVID-19 or flu shots.I am on high-dose steroids or other drugs that weaken my immune system.I have experienced a slow decline in my memory and daily functioning over the last year.I have not had major surgery or lost a significant amount of blood in the last 4 weeks.I do not have any major active neurological diseases, except for Alzheimer's or mild cognitive impairment.I cannot safely undergo a spinal tap due to bleeding disorders or certain medications.Your score on a memory and thinking test is between 12 and 28.Your body mass index (BMI) is between 18.5 and 35, which is a measure of your weight in relation to your height.
- Group 1: MK-2214
- Group 2: Placebo
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are any new participants being accepted into this examination?
"Affirmative, the clinical trial is still in search of participants. Initially published on September 20th 2022, this medical research was last updated on November 15th of that same year (2022)."
What potential risks does MK-2214 pose to individuals?
"Due to the limited amount of data regarding MK-2214's safety and efficacy, our team assign this medication a score of 1 on their risk assessment scale."
How many locations are overseeing the implementation of this trial?
"This trial is being run out of 8 strategic locations, including Hallandale Beach, Long Beach and Hollywood. To reduce the burden on participants, it is advised to select a clinic close by when enrolling in this study."
Does eligibility for this research study extend to those under the age of 30?
"Elderly patients aged between 50 and 80 are currently being recruited for this medical trial."
How many volunteers have registered for the trial thus far?
"Affirmative. Clinicaltrials.gov reveals that this medical trial, which initially went live on September 20th 2022, is actively looking for research participants. The experiment requires 48 patients to be recruited from 8 different clinical sites."
What is the eligibility criteria for participation in this experiment?
"Alzheimer's disease sufferers aged 50 to 80 are currently being recruited for this medical trial. To be eligible, participants must demonstrate general good health, have a BMI between 18.5-35 kg/m2, display gradual decline in mental and physical function over the course of one year prior to screening with MMSE scores >12 and <28 as well as MHIS score <4 at the pre-study visit."
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
Why did patients apply to this trial?
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