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MyTAP oral appliance plus mouth shield for Mild Cognitive Impairment

N/A
Waitlist Available
Research Sponsored by The University of Texas at Dallas
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Participants who can safely have an MRS scan
Have motor abilities including the use of the right arm and hand for neuropsychological testing.
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 weeks
Awards & highlights

Study Summary

This trial will test if dental intervention can help improve brain health in terms of sleep and cognition in people with Alzheimer's disease, mild cognitive impairment, and cognitively normal adults.

Eligible Conditions
  • Mild Cognitive Impairment
  • Cognitive Impairment
  • Sleep Disorder
  • Alzheimer's Disease
  • Energy Metabolism

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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should do so People who can have an MRS scan without any danger should do so.
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Can perform tasks that involve the use of the right arm and hand, including neuropsychological testing.
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This person is not pregnant and is not taking hormone replacement therapy.
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The study looked at adults aged 55 to 85 years.
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or MCI), a significant minority of older adults reported that they had difficulty remembering the names of people they knew well
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You are right-handed.
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You have at least 12 years of education.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Sleep Improvement with MyTAP oral airway management intervention
Secondary outcome measures
Executive function cognitive domain improvement after airway management intervention
Memory cognitive domain improvement after airway management intervention

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Dental Intervention to improve sleep and cognitionExperimental Treatment1 Intervention
To investigate if MyTAP oral airway management with mouth shield will improve sleep and cognition in three cohorts: cognitively healthy adults, mild cognitive impairment, and Alzheimer's disease between the age of 55-85 years.
Group II: Brain Energy Metabolism and Sleep on cognitionActive Control1 Intervention
In the phase-1 of the study, the investigator will be investigating the basic science of the relationship of sleep abnormalities, genes, brain energy metabolites variables with cognitive performance in three cohorts: cognitively normal adults, mild cognitive impairment, and Alzheimer's disease between the age of 55-85 years.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
MyTAP oral appliance plus mouth shield
2018
N/A
~50

Find a Location

Who is running the clinical trial?

Texas A & M University Baylor College Of DentistryOTHER
4 Previous Clinical Trials
173 Total Patients Enrolled
University of Texas, Southwestern Medical Center at DallasOTHER
14 Previous Clinical Trials
20,230 Total Patients Enrolled
The University of Texas at DallasLead Sponsor
57 Previous Clinical Trials
106,201 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who else is applying?

What state do they live in?
California
Texas
How old are they?
18 - 65
65+
What site did they apply to?
Center for BrainHealth, The University of Texas at Dallas
What portion of applicants met pre-screening criteria?
Met criteria
Did not meet criteria
~7 spots leftby Mar 2025