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Atypical Antipsychotic

Risperdal for Schizophrenia

Phase 4
Waitlist Available
Led By Steven G Potkin, M.D.
Research Sponsored by University of California, Irvine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up approximately 6-10 weeks
Awards & highlights

Study Summary

The purpose of this study is to better understand brain function and psychiatric and neurological illness when taking Invega or Risperdal. The objective is to compare the brain effects of Invega to Risperdal in patients with Schizophrenia. This comparison will be evaluated with PET imaging, fMRI, and neurological ratings and assessments.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~approximately 6-10 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and approximately 6-10 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Comparison of BOLD signal activation and FDG metabolism of the DLPFC, superior temporal gyrus and amygdala, and their interaction between Invega and Risperdal

Trial Design

2Treatment groups
Experimental Treatment
Group I: RisperdalExperimental Treatment1 Intervention
Risperdal 2-8mg per day
Group II: InvegaExperimental Treatment1 Intervention
Invega 6-12mg per day
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Risperidone
FDA approved
Paliperidone
FDA approved

Find a Location

Who is running the clinical trial?

University of California, IrvineLead Sponsor
542 Previous Clinical Trials
1,921,905 Total Patients Enrolled
3 Trials studying Schizophrenia
174 Patients Enrolled for Schizophrenia
Janssen, LPIndustry Sponsor
159 Previous Clinical Trials
307,344 Total Patients Enrolled
26 Trials studying Schizophrenia
7,060 Patients Enrolled for Schizophrenia
Steven G Potkin, M.D.Principal InvestigatorUC Irvine

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Contrasting the Brain Effects of Risperidone and Invega With Functional Magnetic Resonance Imaging (fMRI) and Positron Emission Tomography (PET) Scanning
2009. "Contrasting the Brain Effects of Risperidone and Invega With Functional Magnetic Resonance Imaging (fMRI) and Positron Emission Tomography (PET) Scanning". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00937261.
All > Aging > Invega
~6 spots leftby Apr 2025
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