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Antibacterial Agent

Neosporin for COVID-19

Phase 1
Waitlist Available
Led By Charles Dela Cruz, MD
Research Sponsored by Yale University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up from baseline up to month 1
Awards & highlights

Study Summary

This trial will test if neosporin can help increase local immunity in the nose compared to a placebo control.

Eligible Conditions
  • COVID-19
  • Coronavirus

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~from baseline up to month 1
This trial's timeline: 3 weeks for screening, Varies for treatment, and from baseline up to month 1 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Biological Assay
Change in RNA expression profile of ISGs using single cell RNAseq assay
Change in in interferon response gene expression profile from nasal samples collected measured by RT-PCR
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: NeosporinExperimental Treatment1 Intervention
Neosporin will be distributed by the Yale Investigational Pharmacy. Subjects are to use Neosporin twice a day for 7 days.
Group II: Vaseline or equivalentPlacebo Group1 Intervention
Vaseline or equivalent will be distributed by the Yale Investigational Pharmacy. Subjects are to use Vaseline twice a day for 7 days.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Neomycin
FDA approved

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

Bill and Melinda Gates FoundationOTHER
407 Previous Clinical Trials
22,924,021 Total Patients Enrolled
14 Trials studying COVID-19
96,566 Patients Enrolled for COVID-19
Yale UniversityLead Sponsor
1,847 Previous Clinical Trials
2,736,461 Total Patients Enrolled
26 Trials studying COVID-19
541,903 Patients Enrolled for COVID-19
Charles Dela Cruz, MDPrincipal InvestigatorYale University

Media Library

Neosporin (Antibacterial Agent) Clinical Trial Eligibility Overview. Trial Name: NCT05449392 — Phase 1
COVID-19 Research Study Groups: Neosporin, Vaseline or equivalent
COVID-19 Clinical Trial 2023: Neosporin Highlights & Side Effects. Trial Name: NCT05449392 — Phase 1
Neosporin (Antibacterial Agent) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05449392 — Phase 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Has Neosporin been formally authorized by the FDA?

"The safety profile of Neosporin has been assessed as a 1 on our organization's rating scale, due to its status as a Phase 1 trial. This suggests that there is only minimal evidence supporting the medication's efficacy and security."

Answered by AI

Are individuals outside of the age range 65 and below being considered for this experiment?

"The accepted age range for this medical trial is 18 to 60. Participants aged below 18 and over 65 years old are instead directed towards 140 different studies or 911 separate clinical trials respectively."

Answered by AI

How many individuals are involved in this trial's experimentation?

"Affirmative. According to clinicaltrials.gov, the recruitment for this medical study is open as of September 1st 2022 and was recently updated on 12th of same month. The trial requires 46 participants from a single site."

Answered by AI

Is it feasible for me to participate in this medical research?

"This medical trial seeks 46 individuals suffering from covid-19 that are between 18 and 60 years old. The necessary criteria for enrollment includes: providing informed consent, being negative to the virus within 48 hours of joining based on PCR or antigen test (in case a participant tests positive, they will be given further instructions), demonstrating good general health in their history, having the ability to take nasal medication and abiding by its regimen."

Answered by AI

Is this experiment currently recruiting participants?

"Affirmative, the information on clinicaltrials.gov demonstrates that this investigation is recruiting individuals at present. It was first posted on September 1st 2022 and has since been updated as of September 12th 2022. 46 participants are needed from a solitary medical centre for the trial to be successful."

Answered by AI
~26 spots leftby Apr 2025