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Polyamine

Spermidine Supplementation for Healthy Subjects

N/A

Waitlist Available

Led By Kathleen Kelley, MD

Research Sponsored by Chrysea Labs Lda

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, one week, and one month. change will be evaluated between: (i) baseline, (ii) post-1 week, (iii) post washout crossover baseline, (iv) post 1 week, and (v) post 4 weeks.

Awards & highlights

Study Summary

This trial will explore the biological effects of spermidine, a naturally occurring compound found in food, on aging-related biology, like immunity and antioxidation.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, and one month

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, and one month

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, and one month for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Evaluation of molecular biology and bioeffect signalling using untargeted and targeted Metabolomics

Secondary outcome measures

Autophagy assay

CRP marker of inflammatory activity

Polyamine levels in urine and blood

+2 more

Trial Design

2Treatment groups

Active Control

Group I: activeActive Control1 Intervention

oral spermidine supplement

Group II: placeboActive Control1 Intervention

matching placebo

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Chrysea Labs LdaLead Sponsor

1 Previous Clinical Trials

6 Total Patients Enrolled

Kathleen Kelley, MDPrincipal InvestigatorBiofortis Innovation Services Addison, IL, United States, 60101

6 Previous Clinical Trials

665 Total Patients Enrolled

Media Library

Spermidine (Polyamine) Clinical Trial Eligibility Overview. Trial Name: NCT05459961 — N/A

Healthy Subjects Research Study Groups: active, placebo

Healthy Subjects Clinical Trial 2023: Spermidine Highlights & Side Effects. Trial Name: NCT05459961 — N/A

Spermidine (Polyamine) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05459961 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any available spots in this experiment at present?

"As indicated by clinicaltrials.gov, this medical study is not actively recruiting at present; it was initially posted on August 14th 2022 and last updated June 20th of the following year. Despite that, there are 784 other trials currently searching for participants."

Answered by AI

Are individuals aged 80 and over being enrolled in this research?

"This experiment aims to recruit individuals aged 50-70. Meanwhile, there are a total of 55 clinical trials specifically for minors and 364 studies that accept candidates over the age of 65."

Answered by AI

Am I able to participate in this research study?

"This clinical trial is recruiting 42 individuals of Caucasian descent between the ages 50 and 70 that are in generally good health. Applicants must not have used nicotine products, marijuana or hemp based substances within 6 months prior to enrollment and be willing to maintain pre-existing habits like exercise, dieting, etc. Furthermore, no medical condition should prevent them from completing the study requirements as judged by a Clinical Investigator. Finally they need to understand what's involved with this project and provide their consent before joining."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Metabolic Responses to Spermidine Supplementation.

2022. "Metabolic Responses to Spermidine Supplementation.". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05459961.