Clinical Trials in Toronto, ON

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98 Phase 3 Trial · 6506 Toronto Clinics

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Clinical Trials Clinical Trials in Toronto, ON

Reviewed by Michael Gill, B. Sc.

Image of Sunnybrook Health Sciences Centre in Toronto, Canada.

Phase-Based Progress Estimates

Treatment Armfor Melanoma

The objective of this study is to examine the safety profile and therapeutic efficacy of MRI-guided focused ultrasound microbubble therapy and radiotherapy in humans.

Sunnybrook Health Sciences CentreDr. Gregory Czarnota, MD, Ph.D.

Image of Dr. Anil K. Gupta Medicine Professional Corporation in Toronto, Canada.

Phase-Based Progress Estimates

GS-5245for COVID19 (disease)

The goal of this study is to test if GS-5245 is safe and effective for the treatment of coronavirus disease 2019 (COVID-19) in participants who have a high risk of developing serious or severe illness. The study will also measure how much GS-5245 gets into the blood and how long it takes the body to get rid of it.

Dr. Anil K. Gupta Medicine Professional CorporationGilead Study DirectorGilead Sciences

Image of Neighborhood Healthcare Institute of Health in Escondido, United States.

Phase-Based Progress Estimates

Tirzepatidefor Overweight

This trial will look at whether tirzepatide can reduce obesity-related health problems and death in adults.

Neighborhood Healthcare Institute of Health (+78 Sites)Call 1-877-CTLILLY (1-877-285-4559 or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)Eli Lilly and Company

Image of St. Bernards Medical Center in Jonesboro, United States.

Phase-Based Progress Estimates

Imlunestrantfor Breast Cancer

This trial is testing whether immunestrant works better than standard hormone therapy for people with early breast cancer who are estrogen receptor positive and human epidermal receptor 2 negative.

St. Bernards Medical Center (+28 Sites)Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)Eli Lilly and Company

Image of University Health Network - Toronto Western Hospital in Toronto, Canada.

Phase-Based Progress Estimates

Intervention Groupfor Axial Spondyloarthritis (AxSpA)

Despite the known benefits of physical activity, the majority of Canadians fail to meet recommended guidelines. Patients with axial spondyloarthritis (axSpA) also fail to meet recommended guidelines. Exercise, a critical component of physical activity, is considered the cornerstone of axSpA management. Simple health technologies such as mobile phone messaging and email can be useful tools to increase engagement in regular physical activity among the general public and patients with chronic disease. As such, the aim of this research project is to develop and test a patient-centered strategy that provides education on the importance of physical activity and utilizes existing health technologies (such as smart phone applications) to encourage regular participation in physical activity. The results of this study are expected to demonstrate that patients with axSpA will increase their daily engagement in physical activity, and therefore improve symptoms, function and overall quality of life.

University Health Network - Toronto Western HospitalLaura Passalent

Image of Sunnybrook Health Sciences in Toronto, Canada.

Phase-Based Progress Estimates

Arm 1 - Megestrolfor Endometrial Cancer

This is a single centre, single arm, open label, preoperative window of opportunity study. Grade 2 endometrioid endometrial carcinoma patients awaiting surgery will be prospectively recruited to receive a pre-operative progestin therapy course. Therapy response will be histologically evaluated and correlated with clinical and molecular data by comparison of responders vs. non-responders pre- and post-treatment tumor samples.

Sunnybrook Health SciencesBojana Djordjevic, MD

Image of Piedmont Atlanta Hospital in Atlanta, United States.

Phase-Based Progress Estimates

OCE-205for Acute Kidney Injury

This trial is testing a new drug to treat people who have developed a complication of cirrhosis called acute kidney injury. The drug will be given through an IV, and the goal is to see if it is safe and effective.

Piedmont Atlanta Hospital (+14 Sites)Chief Medical and Scientific OfficerOcelot Bio, Inc

Image of City of Hope in Duarte, United States.

Phase-Based Progress Estimates

Daratumumabfor Amyloidosis

This trial is testing a new cancer treatment to see if it is safe for people with heart problems. The new treatment is a combination of drugs, and the trial will also look at how well it works in people of different racial and ethnic backgrounds.

City of Hope (+17 Sites)Janssen Research & Development, LLC Clinical TrialJanssen Research & Development, LLC

Image of Cahaba Research, Inc. - Pelham in Pelham, United States.

Phase-Based Progress Estimates

MRNA-1647for Cytomegalovirus Infections

This trial is testing a new vaccine for CMV, a virus that can cause problems for pregnant women and their babies. The vaccine is being tested for safety and whether it works.

Cahaba Research, Inc. - Pelham (+88 Sites)ModernaTX, Inc.

Image of Alaska Oncology and Hematology LLC in Anchorage, United States.

Phase-Based Progress Estimates

Bemarituzumabfor Cancer of Stomach

This trial is testing if adding the drug bemarituzumab to standard chemotherapy can help people with colorectal cancer live longer.

Alaska Oncology and Hematology LLC (+10 Sites)MDAmgen

Image of The Angeles Clinic in Los Angeles, United States.

Phase-Based Progress Estimates

DAY101for Melanoma

This trial is testing a new treatment for cancer that targets a patient's specific genetic makeup.

The Angeles Clinic (+9 Sites)Day One Biopharmaceuticals, Inc.

Image of University of Alabama at Birmingham Hospital in Birmingham, United States.

Phase-Based Progress Estimates

CC-92328for Multiple Myeloma

This trial is testing a new drug for people with multiple myeloma who have relapsed or are refractory to other treatments. The goal is to see if the drug is safe and tolerable and if it has any preliminary biological or clinical activity.

University of Alabama at Birmingham Hospital (+16 Sites)Marie Nguyen, MDCelgene

Image of University of Minnesota in Minneapolis, United States.

Phase-Based Progress Estimates

CC-96673for Lymphoma, Diffuse

This trial is testing a new drug to see if it is safe and effective for people with a certain type of cancer that has come back or does not respond to other treatments.

University of Minnesota (+8 Sites)Eric Kim, MDCelgene

Image of Novo Nordisk Investigational Site in Lomita, United States.

Phase-Based Progress Estimates

Semaglutidefor Alzheimer Disease

FDA Approved Drug

This trial is to test whether the medication semaglutide has a positive effect on early Alzheimer's disease. The study will last for up to 173 weeks, and participants will have 17 clinic visits and 1 phone call with the study doctor. The study includes various tests and scans, and at 10 of the clinic visits participants will have blood samples taken. The trial is only for women.

FDA Approved Drug

Novo Nordisk Investigational Site (+35 Sites)Clinical Transparency (dept. 1452)Novo Nordisk A/S

Image of University of Alabama at Birmingham in Birmingham, United States.

Phase-Based Progress Estimates

ACE-536for Myeloproliferative Disorders

FDA Approved Drug

This trial is studying how well luspatercept works in treating patients with myeloproliferative neoplasm-associated myelofibrosis and anemia who are on concomitant Janus kinase 2 inhibitor therapy and who require red blood cell count transfusions.

FDA Approved Drug

University of Alabama at Birmingham (+27 Sites)Torsten Gerike, MDCelgene

Image of City of Hope Comprehensive Cancer Center in Duarte, United States.

Phase-Based Progress Estimates

Radiation Therapyfor Malignant neoplasm of prostate

FDA Approved Drug

This trial is testing two different intensities of hormone therapy and radiation therapy, comparing them to the current standard of care, in order to determine the best treatment plan for patients with high risk prostate cancer.

FDA Approved Drug

City of Hope Comprehensive Cancer Center (+99 Sites)Paul L Nguyen

Image of NorthEast Epilepsy Group in Hackensack, United States.

Phase-Based Progress Estimates

EPX-100 (Clemizole HCl)for Syndrome

This trial will test if EPX-100 is a safe and effective treatment for Dravet Syndrome.

NorthEast Epilepsy Group (+15 Sites)Hahn-Jun Lee, M.Sc, Ph.D.Epygenix

Image of City of Hope in Duarte, United States.

Phase-Based Progress Estimates

Afamitresgene Autoleucel (previously ADP-A2M4)for Synovial Sarcoma

This trial is studying a new treatment for synovial sarcoma and MRCLS.

City of Hope (+18 Sites)Deijka Aruajo, MDAdaptimmune

Image of University of California Davis Medical Center in Sacramento, United States.

Phase-Based Progress Estimates

Frequency: Every 6 Monthsfor Neoplasm Metastasis

This trial will help determine if a more frequent or less frequent surveillance strategy for extremity STS patients after surgery impacts patient survival rates.

University of California Davis Medical Center (+19 Sites)Michelle Ghert, MD, FRCSC

Image of University of Alabama at Birmingham Cancer Center in Birmingham, United States.

Phase-Based Progress Estimates

Pembrolizumabfor Stage IIIB Uterine Corpus Cancer AJCC v8

FDA Approved Drug

This trial is studying the combination of pembrolizumab, paclitaxel, and carboplatin to treat endometrial cancer.

FDA Approved Drug

University of Alabama at Birmingham Cancer Center (+99 Sites)Ramez N Eskander

Image of University of Maryland Medical Centre in Baltimore, United States.

Phase-Based Progress Estimates

Ketotifen Fumarate - 5mgfor Contracture

FDA Approved Drug

This trial is testing whether ketotifen can prevent post-traumatic contractures (reduced range of motion due to scarring after an injury).

FDA Approved Drug

University of Maryland Medical Centre (+15 Sites)Kevin A Hildebrand, MD, FRCSC

Image of University of Nebraska - Nebraska Medical Center in Omaha, United States.

Phase-Based Progress Estimates

Stress Ulcer Prophylaxis (Pantoprazole)for Hemorrhage

FDA Approved Drug

This trial is testing whether a drug called pantoprazole decreases acid production in the stomach to prevent ulcers and bleeding in ICU patients who need breathing machines. The trial will also study whether pantoprazole has any harmful effects, such as lung or bowel infections.

FDA Approved Drug

University of Nebraska - Nebraska Medical Center (+44 Sites)Deborah Cook, MD

Image of University of Alabama in Birmingham, United States.

Phase-Based Progress Estimates

Apixabanfor Stroke

FDA Approved Drug

This trial is testing whether apixaban is better than aspirin at preventing another stroke in patients who have had a cryptogenic ischemic stroke and have atrial cardiopathy.

FDA Approved Drug

University of Alabama (+99 Sites)Mitchell SV Elkind, MDBristol-Myers Squibb

Image of Halton Region Paramedic Services in Toronto, Canada.

Phase-Based Progress Estimates

Comparison 2: Liberal Fluidsfor Pyemia

FDA Approved Drug

This trial will help to determine whether paramedics can improve survival for patients with sepsis by providing early treatment.

FDA Approved Drug

Halton Region Paramedic Services (+2 Sites)Damon Scales, MD PhD FRCPC

Image of Children's Hospital of Alabama in Birmingham, United States.

Phase-Based Progress Estimates

Cyclophosphamidefor Medulloblastoma

FDA Approved Drug

This trial is testing how well reduced doses of radiation therapy to the brain and spine, plus chemotherapy, work in treating patients with a certain type of brain tumor.

FDA Approved Drug

Children's Hospital of Alabama (+99 Sites)Nicholas J Gottardo

25 Toronto Clinical Trials Near Me

Top Cities for Toronto Clinical Trials

Image of Toronto in Ontario.

Toronto

254Active Trials

Princess Margaret Cancer CentreTop Active Site

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New York

157Active Trials

Memorial Sloan Kettering Cancer CenterTop Active Site